N/A N=55 Cognitive-Behavioral Therapy for Veterans With TBI
Insomnia · Traumatic Brain Injury
Primary: Change in Insomnia Severity — 8.833; 7.810; 9.625; 8.364 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=73 A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors
Advanced Solid Tumors · Solid Tumors · Ovarian Cancer
Primary: Area Under the Plasma Concentration-Time Profile From Time 0 to 24 Hours (AUC24) of Talazoparib After Multiple Dosing Under Fasted Conditions — 178.7; 173.0…
Phase 2 N=74 Everolimus After (Chemo)Embolization for Liver Metastases From Digestive Endocrine Tumors
Neuroendocrine Tumors · Hepatic Metastases · Metastases
Primary: Rate of Hepatic Progression Free Survival at 24 Months — 47; 20 Participants
Phase 1 N=226 Study of Novel Types 1 and 3 Oral Poliomyelitis Vaccines
Poliomyelitis
Primary: Number of Participants With Serious Adverse Events (SAEs) — 0; 0; 0; 0 Participants
Phase 2 N=205 Hidradenitis Suppurativa Phase 2b Study of Izokibep
Hidradenitis Suppurativa
Primary: Part A: Number of Participants Who Achieved Hidradenitis Suppurativa Clinical Response 75 (HiSCR75) at Week 12 — 12 Participants
Phase 2 N=100 RANKL-blockade for the Treatment of Erosive Osteoarthritis (OA) of Interphalangeal Finger Joints
Hand Osteoarthritis
Primary: Total Ghent University Scoring System (GUSS) of Target Joints at Week 24 — 162.2; 153.3 units on a scale — p=0.024
N/A N=112 LFR-260 vs Traditional Phoropter in Visual Acuity Testing
Visual Acuity · Astigmatism · Anisometropia
Primary: Effectiveness of LFR260 on Visual Acuity Test — 76.6; 76.6 percentage meeting criteria
N/A N=1,050 Temsirolimus (Torisel) Drug Use Investigation (Regulatory Post Marketing Commitment Plan)
Renal Cell Carcinoma
Primary: Number of Participants With Adverse Drug Reactions — 778; 352 Participants
N/A N=129 STandard Versus No Opioid Prescription After Prolapse and Anti-INcontinence Surgery Trial
Postoperative Pain · Opioid Use · Prolapse; Female
Primary: Percentage of Patients Satisfied With Pain Control at 6 Week Postoperative Visit — 59; 58 Participants
Phase 3 N=601 Phase III Palbociclib With Endocrine Therapy vs. Capecitabine in HR+/HER2- MBC With Resistance to Aromatase Inhibitors
Metastatic Breast Cancer
Primary: Progression-Free Survival (PFS) — 7.3; 9.4; 7.5; 10 month
N/A N=30 Nutritional Biomarkers of Sarcopenia
Sarcopenia
Primary: Resting and Maximum Plasma Leucine Concentration — 659; 755; 721; 95 micromoles per liter
Phase 3 N=1,105 Compare Two Copper IUDs: Mona Lisa NT Cu380 Mini and ParaGard
Healthy Women · Female Contraception
Primary: Pregnancy Rate of Mona Lisa Copper IUD Over 3 Years — 1.86 Pearl Index = Num preg per 100 person yr
N/A N=53 Form, Fit, and Function of INVSENSOR00061
Healthy
Primary: INVSENSOR00061 SpO2 Accuracy — 1.02 % of SpO2
N/A N=16 Geriatric-assessment Interventions to Address Functional Deficits in Older Adults w Multiple Myeloma
Multiple Myeloma · Myeloma · Disability Physical
Primary: Intervention Attendance (Feasibility) — 50 percentage of participants
N/A N=503 AsseSSing Impact in pSoriatic Treatment
Psoriatic Arthritis
Primary: Number of Patients Undergoing Treatment Escalation — 160 Participants