17,261 trials
Refractory Plasma Cell Myeloma
Primary: Overall Response Rate — 0.35 proportion of participants
Parkinson Disease · Motor Disorder
Primary: Maximal Change in UPDRS Part III From Predose to Postdose on Day 1 — -22.0; -12.5; -11.2; -15.2 score on a scale
Advanced Breast Cancer · HER2-positive Breast Cancer · Brain Metastases
Primary: 16 Weeks PFS Per Response Assessment in Neuro-Oncology Brain Metastases (RANO-BM) (Cohort 1) — 1; 7 Participants
Type 2 Diabetes
Primary: Glucose — -21.55; 1.92 mg/dL
Cannabis Use Disorder · Multiple Sclerosis
Primary: Change in Kessler Psychological Distress Scale (K10) Score — 6.4; 4.5 score on a scale
Grade 3a Follicular Lymphoma · Recurrent Follicular Lymphoma · Recurrent Grade 1 Follicular Lymphoma
Primary: Maximum Tolerated Dose of Lenalidomide When Given With Obinutuzumab Defined as the Highest Dose Level Have Been Treated With Less Than 2 Instances of Dose Limiting…
Venous Thromboembolism
Primary: Apixaban vs. Enoxaparin - Number of Participants With Bleeding Events — 1; 1 Participants
Measles; Mumps; Rubella; Chickenpox · Measles
Primary: GMC of Anti-measles Antibodies at Day 43 — 801; 788; 728; 682 mIU/mL
PTSD · Stroke
Primary: Change in Modified Rankin Scale at 12 Weeks — -0.44; -0.50 units on a scale — p=0.896
Schizophrenia · Schizoaffective Disorder
Primary: MATRICS Consensus Cognitive Battery (MCCB) — 41.8; 39.67 units on a scale
Cancer · Melanoma
Primary: Number of Participants Experiencing Adverse Events (AEs) - Part 1 — 16; 14; 18; 12 Participants
Neuroendocrine Tumor · Anaplastic Thyroid Cancer · Adenocarcinoma
Primary: Objective Response Rate (ORR) — 0; 2; 2; 2 Participants
Lymphomatoid Granulomatosis · Granulomatosis, Lymphomatoid · Non-Hodgkins Lymphoma
Primary: Overall Response Rate (ORR) — 53.45; 51.85; 57.14; 50.00 percentage of participants
Prostate Cancer
Primary: Percentage of Participants With a Toxicity — 6; 7; 24 Percentage of participants
Myopia
Primary: Axial Length at 36 Months — 25.28; 25.25; 25.33 mm