17,261 trials
Acromegaly
Primary: The Number of Patients Who Achieve a Trough Human Growth Hormone (hGH) Concentration of <2.5µg/L During the Last 12 Hours of the 23 Hour Profile Following Each Study…
Atopic Dermatitis
Primary: Percentage of Participants Achieving Greater Than or Equal to (>=) 50 Percent (%) Reduction From Baseline in Eczema Area and Severity Index (EASI 50) at Week 12 — 48.2…
Post-transplant Lymphoproliferative Disease · Solid Organ Transplant · Stem Cell Transplant (Bone Marrow Transplant)
Primary: Overall Response Rate — 3 Participants
Non-ischemic Dilated Cardiomyopathy
Primary: Incidence of Any Treatment-emergent Serious Adverse Events (TE-SAEs) — 1; 0; 0; 1 Participants
Refractory Chronic Lymphocytic Leukemia · Stage I Chronic Lymphocytic Leukemia · Stage II Chronic Lymphocytic Leukemia
Primary: The Number of Participants With In Vitro Dasatinib Sensitivity in Predicting Clinical Activity — 5; 4; 4; 0 Participants — p=0.0106
Refractory Chronic Cough
Primary: Cough Reflex Sensitivity to Capsaicin in Participants Who Received Gefapixant 100 mg and Placebo (Period 1 & Period 2 Combined) — 3.05; 3.04; 1.72; 1.41 natural log (µM)…
Primary Open-Angle Glaucoma (POAG) · Ocular Hypertension (OHT)
Primary: Mean Intraocular Pressure (IOP) — -6.4; -6.8; -6.4; -7.1 mm of mercury
Adolescent Depression
Primary: Children's Depressive Rating Scale - Revised (CDRS-R) — 50.2; 49.5; 35.2; 36.5 units on a scale
Glaucoma
Primary: Intraocular Pressure — 17.6; 16.4; 20.2; 17.0 mmHg — p=<.05
Exudative Age Related Macular Degeneration
Primary: Change in Central Subfield Thickness on OCT From Baseline to Week 36 — -54; -.1 microns
Refractory Chronic Cough
Primary: Change From Baseline in Awake Objective Cough Frequency After 12 Weeks of Treatment (Day 84) — -0.40; -0.64; -0.65; -0.86 log coughs/hour — p=0.0971
Stable Angina
Primary: Number of Participants With Elevation of Cardiac Enzyme — 4; 2 Participants
Pain
Primary: Numeric Rating Scale (NRS) Summed Pain Intensity Difference (SPID) Over 0 to 48 Hours (NRS SPID-48) After Time 0 — 151.7; 126.4; 149.0 units on a scale
Stress Disorders, Post-Traumatic · PTSD · Depression
Primary: Impact of Event Scale - Revised (IES-R) — 25.76; 36.32 units on a scale
Brain Metastases From Non-small Cell Lung Cancer
Primary: Overall Survival — 185; 209; 209 days — p=0.933