17,261 trials
Graft vs Host Disease · Hematologic Neoplasms · Non-Neoplastic Hematologic and Lymphocytic Disorder
Primary: Percentage of Patients That Experience Grade 2-4 GVHD Within 100 Days of Transplant — 22 percentage of patients
Schizophrenia
Primary: PANSS-EC Change From Baseline — -4.98; -6.71; -8.56 PANSS units — p=0.0880
Anemia
Primary: The Change in Hemoglobin Over Time Between Baseline and End of Initial Treatment Based on Individual Regression Slopes — 0.48; 1.08; 1.34; 0.17 gram/deciliter (g/dL)
Non-Hodgkin's Lymphoma · CNS Lymphoma
Primary: Proportion of Patients With CNS Involvement by B-cell NHL, Relapsed PCNSL, or Relapsed PIOL Who Are Alive and Progression-free at One Year — 28 Participants
Neuroendocrine Tumor · Carcinoid Tumor · Pancreatic Neuroendocrine Tumor
Primary: Objective Response Rate — 0.0 percentage of patients
Adenocarcinoma of the Esophagus · Adenocarcinoma of the Gastroesophageal Junction · Diffuse Adenocarcinoma of the Stomach
Primary: CRLX101 (CPT) Uptake in Tumor and Nearby Normal Tissue — 9; 0; 0; 9 Participants — p=<0.01
Irritable Bowel Syndrome (IBS)
Primary: Number of Participants With Average Adequate Relief Rate During the Last 4 Weeks of the Treatment Periods (Weeks 3-6. in Period 1, Weeks 12-15 in Period 2).
Opiate Dependence
Primary: Naltrexone Injections Received — 51.8; 86.8 Percentage of injections received — p==0.002
Opiate Dependence
Primary: Percentage of Depot Naltrexone Doses Received — 42.2; 80.6 percentage of injections — p==0.008
Sickle Cell Disease
Primary: Percentage of Participants With Event-Free Survival (EFS) — 76; 69 percentage of participants
Cocaine Dependence
Primary: Cocaine Use/Treatment Effectiveness Score (TES) — 6.6; 8.3; 29 percentage of negative urines
Sleep Apnea, Obstructive
Primary: Change in Apnea/Hypopnea Index (AHI) — 7.99; -1.71; -5.21 events/hour
Leukemia
Primary: Continuous Complete Remission at 3 Years — 74 percentage of participants
Breast Cancer · Metastatic Breast Cancer
Primary: Percentage of Participants With Pathologic Complete Response (pCR) — 38.9 percentage of participants
Brain Injuries · Post-Traumatic Headache
Primary: Frequency of Headaches — 10 Participants — p=.101