Phase 4 N=234 Injection Versus Splinting in Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS)
Primary: Symptom Severity and Limitations in Hand Function as Assessed by the BCTQ 6 Weeks — 2.02; 2.29 score on a scale — p=<0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=200 Evaluation of Pre-exposure Prophylaxis Cascade in Pregnant and Breastfeeding Women in Cape Town (Formative Study)
Hiv
Primary: PrEP Retention — 100 participants
Phase 4 N=88 The SLIM Study: Sling and Botox® Injection for Mixed Urinary Incontinence
Mixed Urinary Incontinence · Stress Urinary Incontinence · Urgency Incontinence
Primary: Number of Participants With Self-reported Mixed Urinary Incontinence Symptoms — 31; 34 Participants
Phase 4 N=20 Parcopa Versus Carbidopa-levodopa in a Single Dose Cross-over Comparison Study
Parkinson's Disease
Primary: Measurement of Time in Minutes From When a Patient Was in a Clinical "Off" State, Took Their Medication and Went Into a Clinical "on" State — 23.9; 28.5 minutes
Phase 4 N=427 A 24-Week Treatment Study to Compare Standard of Care Versus the eMDPI DS in Participants 13 Years or Older With Asthma
Asthma
Primary: Number of Participants Achieving Well-Controlled Asthma or Reaching Clinically Important Improvement in Asthma Control — 112; 134 Participants
Phase 4 N=31 Ketamine as an Augmentation Strategy for Electroconvulsive Therapy (ECT) in Depression
Unipolar Depression · Bipolar Depression
Primary: Hamilton Rating Scale for Depression (HRSD) Improvement — 7.82; 8.60 HRSD units
Phase 4 N=10 Pain Control in Pediatric Oncology: Utility of EMLA Cream vs Lidocaine Injection in Lumbar Punctures
Leukemia-Lymphoma
Primary: Post Lumbar Puncture Pain: Wong-Baker Faces Pain Rating Scale — 0; 0; 0; 0 score on a scale
Phase 4 N=41 The Effects of Evolocumab in Patients With Diabetes and Atherosclerotic Vascular Disease
Atherosclerotic Vascular Disease · Type2 Diabetes · Microvascular Dysfunction
Primary: Number of Adverse Events — 13; 13 events
Phase 4 N=46 Platelet Transfusion During Neonatal Open Heart Surgery
Cardiac Disease · Cardiac Surgery · Cardiopulmonary Bypass
Primary: Amount of Blood Products Transfused — 58; 103 milliliter per kilogram (mL/kg)
Phase 4 N=11 Wearing-Off Period of Pharmacological Dilation and Anisocoria
Anisocoria
Primary: Number of Participants With Constricting Response to Pilocarpine 1% in the Pharmacologically Dilated Eye — 3 Participants
Phase 4 N=421 Pain Increases After Shoulder Injection
Shoulder Pain
Primary: Incidence of a Flare Reaction — 44; 8; 149; 191 Person-visits
Phase 4 N=20 A Pilot Study: High Versus Low Oxytocin Dosing for Induction of Labor in Pregnant Patients With Obesity
Pregnant Patients With Obesity
Primary: Number of Participants Delivered by Cesarean — 3; 3 Participants
Phase 4 N=26 Inhaler Lung Deposition in Chronic Obstructive Pulmonary Disease (COPD)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE · ASTHMA · HEALTHY SUBJECTS
Primary: ANALYSIS OF LUNG DEPOSITION - Penetration Index — 0.8; 0.72; 0.69; 0.58 ratio
Phase 4 N=82 Placebo In Chronic Back Pain - Double-Blind Randomized Control Trial
Chronic Low Back Pain
Primary: Change in Pain Assessed by Visual Analogue Scale (VAS) — -0.03; -0.10; -0.21 percentage of change in pain
Phase 4 N=26 Efficacy and Tolerability of Combination Varenicline With Hydroxyzine as a Potential Smoking Cessation Treatment
Smoking Cessation · Stress · Sleep Disturbance
Primary: Change in 10-item Perceived Stress Scale (PSS-10) Following Smoking Cessation (While Taking Arenicline and Hydroxyzine). — -1.38; -1.48; -1.55; -2.05 score on a scale