65,437 trials
Obesity
Primary: Number of Participants With Age- and Sex-adjusted BMI% Greater Than or Equal to 85% — 335; 273; 315; 263 Participants — p=0.68
Ulcerative Colitis
Primary: Percentage of Participants in Cohort 1 Achieving Clinical Remission — 26.5; 1.5 Percentage of participants — p=<.0001
CCM · Cavernoma · Cerebral Cavernous Malformation
Primary: Rate of Recurrent Symptomatic Hemorrhage During the Two Year Follow-up Period in Patients With CASH. — 10; 11 Number of new bleeds
Extensive Stage Small Cell Lung Carcinoma · Limited Stage Small Cell Lung Carcinoma
Primary: Number of Participants With Deterioration in HVLT-R Delayed Recall Score at Six Months (Phase III) — 33; 27 Participants — p=0.28
Cancer
Primary: Number of Participants Compliant With Follow-up Care Visits — 47; 53; 44 Participants
Amyloidosis · Amyloid Cardiomyopathy · Transthyretin Amyloidosis
Primary: A Hierarchical Combination of All-Cause Mortality, Cumulative Frequency of CV-related Hospitalization, Change From Baseline in NT-proBNP and Change From Baseline in 6MWT…
Blood Pressure
Primary: Operator Satisfaction — 8 score on a scale
Sickle Cell Disease
Primary: SCD-specific Knowledge — 32.0; 32.0; 33.5; 33 score on a scale
Bladder Cancer
Primary: Clinical Complete Response (CCR) Rate — 43 Percentage of participants
Plaque Psoriasis
Primary: Percentage of Participants Achieving Greater Than or Equal to (>=) 75% Reduction From Baseline in Psoriasis Area Severity Index (PASI) Score (PASI-75) at Week 16 — 58.3…
Substance Use Disorders
Primary: Alcohol Abstinence — 82.8; 60.2 percentage of participants — p=<0.001
Actinic Keratosis
Primary: Percent Change in the Number of Actinic Keratoses — -75 % change in number of actinic keratoses
Pre-exposure Prophylaxis
Primary: Difference in Tenofovir-diphosphate (TFV-DP) Levels Between Intervention and Control Arms at 6 Months Follow-up — 17; 7 Participants
Neurotoxicity · Liver Transplant; Complications
Primary: Change in Neurotoxicity Burden — -5; -4 score on a scale
Opioid Use · Sedative Use
Primary: Change in Subject-Rated Outcome: Visual Analog Scale (VAS) Drug Liking — 7.40; 39.00; 40.80; 24.50 Score on a scale — p=<0.0001