Clinical Trial Search

Primary: Percentage of Participants With Adverse Events Leading to Discontinuation — 7.1; 12.0; 40.0 percentage of participants

Primary: Mean Sitting Systolic Blood Pressure (msSBP) — -37.72; -30.63 mm Hg

Primary: Change in HbA1c and Compared Between Groups — -0.3122449; 0.1191489 percent HbA1c — p=<0.05

Primary: Overall Survival (OS) (Time-to-Death) Difference Between MDX-010 in Combination With gp 100 Melanoma Peptide Vaccine Versus gp 100 Melanoma Peptide Vaccine Alone — 9.95…

Primary: Change From Baseline in the International Restless Legs Syndrome Rating Scale (IRLS) at Week 52 Using Observed Case (OC) — -16.3; -17.0; -16.8 points on a scale

Primary: Time to Start of Relief of Symptoms From HAE Attack (Intent to Treat (ITT) Subject Population) — 0.46 hours

Primary: Double-blind Period (DB); Number of Participants With American College of Rheumatology (ACR) 20 Response at Day 169 — 129; 26 participants — p=<0.001

Primary: Disease Free Survival [Number of Events] — 164; 140; 1140; 1167 participants

Primary: Leakage (Percent of All Base Plates With Leakage) — 27; 30 Percent of Base plates

Primary: Percentage of Patients Classified as Treatment Success at Week 6, ITT Population — 51.3; 55.9 Percentage of Participants — p=0.4411

Primary: Percentage of Patients Achieving Responder Status at Week 52 — 63.9; 69.0 Percentage of Participants — p=0.6558

Primary: Number of Subjects Who Develop Endoscopically-diagnosed Upper Gastrointestinal Ulcers Confirmed by Endoscopy. — 40; 38 participants — p=0.0018

Primary: Percent Change From Baseline in Lumbar Spine Bone Mineral Density (BMD) at Month 12-Endpoint in Women With Postmenopausal Osteoporosis, Primary Efficacy Population…

Primary: Number of Participants Who Develop Endoscopically-diagnosed Gastric Ulcers — 55; 52 participants — p=<0.0001

Primary: Distribution of Change in Spherical Equivalent Refractive Error From Baseline to 3 Years — 6; 3; 11; 8 participants