65,437 trials
Extraintestinal Pathogenic Escherichia Coli Prevention
Primary: Cohort 1: Number of Participants With Solicited Local (Injection Site) Adverse Events (AEs) for 14 Days After Vaccination on Day 1 — 46; 54; 60; 15 Participants
Meniere Disease
Primary: Number of Vertigo Episodes — 5.41; 5.03; 13.78 number of episodes — p=<0.001
Acute Respiratory Failure · Post-Intensive Care Syndrome
Primary: Self Reported Quality of Life PCS: Physical Component Score at 1 Year — 36.22; 35.29 score on a scale
Short Bowel Syndrome · Parenteral Nutrition Associated Liver Disease
Primary: Number of Participants With AEs and SAEs Following Administration of NST 6179 — 4; 2; 2; 2 Participants
Haemophilus Influenzae Type B Infection
Primary: Anti-PRP IgG Geometric Mean Concentration (GMC) — 0.40; 0.41 μg/mL — p=0.85
Anemia · Kidney Failure, Chronic
Primary: Area Under the Serum Concentration-Time Curve Over Dosing Interval (AUC14d) (14 Days) — 15204.31; 11269.14; 28647.03; 10327.98 day*ng/mL
Cutaneous Lupus Erythematosus
Primary: Percent Change From Baseline in Cutaneous Erythematosus Disease Area and Severity Index - Activity (CLASI-A) Sub-Score at Week 12 — -37.05; -42.76 percent change
Patient Satisfaction
Primary: Patient Satisfaction With Pain Control in Labor — 5; 5 score on a scale — p=0.16
Injuries
Primary: Change in Self Reported Physical Recovery — 40.42; 39.18 score on a scale
Pompe Disease
Primary: Inspiratory Load Compensation - Inspiratory Volume — 288.41; 554.34; 743.71; 927.57 mL
Locally Advanced Pancreatic Adenocarcinoma
Primary: Number of Subjects With Treatment Emergent Adverse Events (Safety and Tolerability) — 3; 3; 4; 23 Participants
Vasoplegic Syndrome · Liver Transplant; Complications
Primary: Systemic Vascular Resistance (SVR) — 480; 410; 588; 420 dyne*sec/cm^5
BRAF V600E Unresectable or Metastatic Melanoma · BRAF V600E Metastatic NSCLC · Melanoma
Primary: Dose Limiting Toxicities (DLTs) Experienced During Cycle 1 — 0 participants
Dry Eye
Primary: Change From Baseline in Ocular Surface Fluorescein Staining Score at Day 28 — -2.9; -2.4 score on a scale
Heart Failure
Primary: Oxygen Uptake (VO2) Peak — 1778.1; 1228.2; 1393.7; 1763.6 ML/KG/Min