Phase 4 N=94 Does PAI Reduce Pain After TKA Among Knee Arthroplasty Patients Receiving ACB & IPACK?
Total Knee Athroplasty
Primary: Pain Scores (NRS, 0-10) With Ambulation on POD1 — 4.55; 4.26 units on a scale — p=0.11
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=40 Metformin Effect on Brain Function in Insulin Resistant Elderly People
Insulin Resistance · Obesity · Obesity, Abdominal
Primary: Change From Baseline in Brain PCr/ATP Ratio as Measured by Phosphorus Magnetic Spectroscopy (31P-MRS) After 10 Months of Metformin Administration — -0.045; -0.016…
N/A N=3 Pilot Human Laboratory Study of Alcohol Approach Bias Modification (AABM) for Alcohol Use Disorder (AUD)
Alcohol Use Disorder
Primary: Recruitment Feasibility — 3 Participants
N/A N=18 Cerebellar tDCS and Balance Training in PwMS
Multiple Sclerosis
Primary: Score on the Berg Balance Scale — 54.43; 51.43; 54.67; 50.33 units on a scale
N/A N=29 Remote Pulmonary Function Testing and Nurse Coaching in ALS
ALS
Primary: Date of Identification of Noninvasive Ventilation (NIV) Need From rPFT Monitoring — 176 days after enrollment
Phase 2 N=80 A Study of CS1001 in Subjects With Relapsed or Refractory Extranodal Natural Killer/ T Cell Lymphoma(ENKTL)
Extranodal Natural Killer/T-Cell Lymphoma
Primary: Objective Response Rate (ORR) Assessed by IRRC — 46.2 percentage of Participants
N/A N=299 Nucleophilic Defense Against PM Toxicity (NEAT Trial)
Air Pollution Toxicity
Primary: Endothelial Progenitor Cells — 0.0025; 0.0027 # cells per CD41 minus cells
N/A N=29 Targeting Normoxia in Neonates With Cyanotic Congenital Heart Disease in the Intra-operative and Immediate Post-operative Period
Hypoplastic Left Heart Syndrome · Total Anomalous Pulmonary Venous Return · Truncus Arteriosus
Primary: Systemic Oxidative Stress Based on Thiobarbituric Acid Reactive Substances (TBARS) — 1.21; 1.93; 1.09; 1.77 Fold Change from Baseline — p=<0.01
Phase 3 N=152 A Study to Evaluate Safety and Immunogenicity of mRNA-1273 Vaccine to Prevent COVID-19 in Adult Organ Transplant Recipients and in Healthy Adult Participants
SARS-CoV-2
Primary: Parts A and B: Number of SOT Participants With Unsolicited Adverse Events (AEs) — 48; 41; 89 Participants
Phase 4 N=580 A Study of Galcanezumab (LY2951742) in Adult Participants With Episodic Migraine
Migraine · Episodic Migraine
Primary: Percentage of Participants With 50% Response Rate Across the 3-month Treatment Period. — 62; 61 percentage of participants — p=0.695
N/A N=42 e-Motivación: Developing and Pilot Testing an App to Improve Latinos' Screening Colonoscopy Rates
Colorectal Cancer
Primary: Colonoscopy Completion — 19; 19 Participants
Phase 2 N=12 Safety, Dose Tolerance, Pharmacokinetics, Pharmacodynamics of CPX-POM in Patients With Newly Diagnosed or Recurrent Bladder Tumors
Bladder Cancer
Primary: Number of Participants With Any Serious Adverse Events (SAEs) — 1 Participants
Phase 2 N=5 Effect of Cannabis and Endocannabinoids on HIV Neuropathic Pain
Cannabis · HIV Neuropathy · Pain Syndrome
Primary: Phase 1 - Numerical Pain Rating Scale (NPRS) — 2.2; 2.6; 2.8; 1.4 units on a scale
Phase 1 N=13 Study to Assess the Safety and PK of Oral and IV Xenleta in Adults With Cystic Fibrosis
Cystic Fibrosis
Primary: The Median for Lefamulin and Its Main Metabolite BC-8041 for PK Plasma Parameter Tmax in Cystic Fibrosis (CF) Patients. — 2.00; 0.583; 1.517; 1.500 hours
N/A N=53 Effect of Blood Flow Restriction Resistance Exercises in COPDAE In-patient Rehabilitation
Chronic Obstructive Pulmonary Disease · Acute Exacerbation of COPD
Primary: Change of Maximal Voluntary Isometric Contraction (MVIC) of Knee Extension of the Dominant Leg in 3 Weeks — 25.9; 24.7 kgf