12,372 trials
Myeloid Leukemia, Chronic
Primary: Number of Participants With Best Confirmed Complete Cytogenetic Response (cCCyR) Within 12 Months — 204; 177 Participants — p=0.0056
Common Variable Immunodeficiency · X-linked Agammaglobulinemia · Autosomal Recessive Agammaglobulinemia
Primary: Total Serum IgG Trough Levels — 8.10; 7.49 g/L
Metastatic Colorectal Cancer
Primary: Progression-Free Survival (PFS) — 11.0; 8.3 months
Metastatic Breast Cancer
Primary: Overall Survival — 29.2; 16.3 months — p=0.3348
Organ Transplantation, Renal Transplantation
Primary: Renal Function Measured by Calculated Glomerular Filtration Rate (GFR Calculated According to the Nankivell Formula) — 68.5; 69.2; 63.6; 68.3 mL/min per 1.73 m^2
Cystic Fibrosis
Primary: Time to Need for Inhaled or Intravenous (IV) Antipseudomonal Antibiotics — 71; 92 Days — p=0.0070
Heart Defects, Congenital
Primary: Number of Participants Reaching Primary Endpoint Criteria (First Occurrence of Death / Shunt Thrombosis / Cardiac Procedure < 120 Days Considered of Thrombotic Nature)…
Asthma
Primary: Morning Peak Expiratory Flow (mPEF) — 3.3 L/min
Obstructive Sleep Apnea Syndrome
Primary: Percentage of Oxygen Saturation in the Brain During Sleep — 53.462; 53.13 Percentage of brain oxygen saturation
Cystic Fibrosis
Primary: Number of Participants Reporting Adverse Events (AEs) — 83; 185; 30; 79 participants
Parkinson's Disease
Primary: Time to First Occurrence of Dyskinesia — 90.7; 117.1 weeks
Psoriasis Vulgaris
Primary: Subjects With "Controlled Disease" ("Clear" or "Almost Clear" Disease) According to Investigator's Global Assessment of Disease Severity at Week 8 — 73; 33; 5…
Osteoarthritis Knee Pain
Primary: Change From Baseline to 13 Week Endpoint (Baseline Observation Carried Forward [BOCF]) in Brief Pain Inventory (BPI) "24-Hour Average Pain" Item (Question 3) of the…
Open Angle Glaucoma · Ocular Hypertension
Primary: Mean Intraocular Pressure at 9:00 am — 17.9; 18.1 mmHg
Asthma
Primary: Mean Area Under the Time Curve From 0 to 12 Hours (AUC(0-12 Hours)) of Change From Baseline to Week 12 in Forced Expiratory Volume (Liters) in 1 Second (FEV1) — 4.19…