Phase 3 N=30 Adapalene Gel 0.3% Versus Tretinoin 0.05% Emollient Cream for Treatment of Photodamage
Photoaging
Primary: Change From Baseline in Overall Integrated Assessment of Photodamage at Week 24 — 6; 10 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=18 Changes in Adrenal Hormones During Adrenal Radiofrequency Ablation
Adrenal Tumors
Primary: Increase in Catecholamine
Phase 3 N=23 Study to Evaluate the Efficacy of Infliximab Induction Therapy for Patients With Palmoplantar Psoriasis (PPP)(Study P04555)(COMPLETED)
Psoriasis
Primary: Number of Participants Who Achieve at Least 75% Improvement in Palmoplantar Psoriasis Activity Severity Index (PPPASI) After 3 Infusions. — 4 participants
Phase 3 N=37 Long-term Immune Persistence of GSK Biologicals' Combined Hepatitis A & B Vaccine Injected According to a 0,1,6 Mth Schedule in Healthy Adults
Hepatitis B · Hepatitis A
Primary: Number of Subjects With Anti-hepatitis A (Anti-HAV) Antibody Concentrations Equal to or Above Cut-off Value — 25; 28; 23; 24 Participants
Phase 3 N=1,198 Cetuximab Combined With Irinotecan in First-line Therapy for Metastatic Colorectal Cancer (CRYSTAL)
Epidermal Growth Factor Receptor (EGFR) Expressing Metastatic Colorectal Cancer
Primary: Progression-free Survival (PFS) Time - Independent Review Committee (IRC) Assessments — 8.9; 8.0 months — p=0.0479
Phase 3 N=270 A Treatment Combination for Patients With Unresectable Stage III or Stage IV Melanoma
Melanoma
Primary: Progression Free Survival (PFS) — 122; 125 days — p=0.492
Phase 3 N=124 Efficacy of SLITone in House Dust Mite Allergic Patients
Allergy
Primary: Average Daily Asthma Medication Score During a 2-months Evaluation Period in Autumn 2008 — 4.4; 4.7 Scores on a scale — p=0.85
Phase 3 N=109 Canadian Cardiology de Novo Study: A Comparison Between Tacrolimus- and Cyclosporine- Based Immunoprophylactic Regimens
Heart Diseases · Heart Transplantation
Primary: The Change in the Markers of Growth, Apoptosis, Inflammation and Oxidation Measured in Endomyocardial Biopsies — 0.70; 0.90; 0.87; 0.79 Densitometry / Densitometry of…
Phase 3 N=89 A Phase III Open-Label Study Of Gabapentin As Adjunctive Therapy In Japanese Pediatric Patients With Partial Seizures
Epilepsies, Partial
Primary: Response Ratio of Gabapentin in Japanese Pediatric Patients With Partial Seizures — -0.158 ratio
Phase 3 N=332 PillCam™ Colon Capsule Endoscopy (PCCE) in the Visualization of the Colon
Colonic Diseases
Primary: Number of Participants With Successful Capsule Endoscopies or Standard Colonoscopies — 322; 326 participants
Phase 3 N=20 Short Incubation Methylaminolevulinate Photodynamic Therapy Without Occlusion
Actinic Keratosis
Primary: Mean Number of Facial Actinic Keratoses at Week 12 — 2.70 Lesions
Phase 3 N=105 Study Evaluating a 13-valent Pneumococcal Conjugate Vaccine in Elderly Subjects
Vaccines, Pneumococcal Conjugate Vaccine
Primary: Pneumococcal OPA Geometric Mean Titers (GMTs) for the 13 Serotypes 1 Month After 13vPnC / 23vPS / 13vPnC (Vaccination 3) Versus 1 Month After 13vPnC (Vaccination 1)…
Phase 3 N=362 Study of Milnacipran Added to Pregabalin for Treatment of Fibromyalgia
Fibromyalgia
Primary: Patient Global Impression of Change (PGIC) Responder Rate at End of Study — 36; 83; 137; 96 participants — p=<0.001
Phase 3 N=6 Effect on Bacterial Glycolytic Acid Formation on Plaque
Dental Plaque
Primary: ph of Dental Plaque After Sucrose Challenge — 4.88; 5.04; 4.98 ph of dental plaque — p=0.05
Phase 3 N=1,491 Docetaxel in Node Positive Adjuvant Breast Cancer
Breast Cancer
Primary: Number of Participants With Disease-Free Survival Events — 287; 333 Participants — p=0.0043