12,372 trials
Multiple Sclerosis
Primary: Time to Clinically Definite Multiple Sclerosis (CDMS) Represented by Kaplan-Meier Estimates of the Cumulative Percentage of Participants With CDMS at Selected Points in…
Depressive Disorder, Major
Primary: Change From Baseline in Hamilton Depression Scale (HAM-D) at Week 12 — -12.61; -10.50 Scores on a scale — p=0.002
Allergic Conjunctivitis
Primary: Lid and Lid Margin Erythema, Change From Baseline — 0; 0 Units on a scale
ADHD
Primary: Change From Baseline in Attention Deficit Hyperactivity Disorder Rating Scale-fourth Edition (ADHD-RS-IV) Total Score at Week 8 - Last Observation Carried Forward (LOCF)…
Allergic Conjunctivitis
Primary: Lid and Lid Margin Erythema, Change From Baseline — 0; 0 Units on a scale
Partial Epilepsies
Primary: Number of Subjects Reporting at Least 1 Treatment-Emergent Adverse Event (TEAE) During the Treatment Period (Maximum 6 Years) — 288 subjects
Overactive Bladder Syndrome
Primary: Numerical Change From Baseline in Micturition-Related Urgency Episodes Per 24 Hours at Week 12 — -3.2; -2.9 number of episodes — p=0.1959
Psoriasis
Primary: Percentage of Participants With a Physician's Global Assessment of Clear or Minimal at Week 16 of Period R — 76.5 percentage of participants
Infections, Streptococcal
Primary: Concentrations of Antibodies Against Vaccine Components of the Pneumococcal Vaccine — 2.67; 2.46; 3.95; 3.14 μg/mL
Pulmonary Hypertension
Primary: Change From Baseline to Week 24 in 6 Minute Walk Distance (6MWD) — 20.5 meters — p=<0.001
Allergic Rhinitis
Primary: Change From Baseline in Participant's AM/PM PRIOR Total 5 Symptom Score (T5SS) Over Days 1 to 29 of Treatment — 9.63; 9.55; -3.76; -2.87 units on a scale — p=<.001
Bacterial Infections
Primary: Clinical Cure Rate at Test of Cure (TOC) (MITT Population) — 291; 289; 25; 28 participants
Erectile Dysfunction
Primary: Change From Baseline Between Tadalafil Once a Day (OaD) and Sildenafil as Needed (PRN) in Sexual Self-Confidence Domain of Psychological and Interpersonal Relationship…
Benign Prostatic Hyperplasia
Primary: Change From Baseline to 12 Weeks, International Prostate Symptom Score (IPSS) — -5.6; -3.6 Units on a Scale — p=0.004
Infections, Rotavirus · Rotavirus Vaccines
Primary: Number of Subjects Reporting Any Rotavirus (RV) Gastroenteritis (GE) Leading to Medical Intervention and Caused by the Circulating Wild-type RV Strains — 14; 34 subjects