12,372 trials
Allergic Rhinitis · Asthma
Primary: The Change of the Rhinasthma Global Summary Score From Baseline to Endpoint After 28 Days of Treatment. — 25.3; 26.7; -10.3; 0.4 units on a scale — p=0.001
Growth Disorders · Insulin-Like Growth Factor-1 Deficiency
Primary: Height Velocity During the First Year - Intent to Treat (ITT)Population — 5.2; 6.9; 7.7 cm/yr — p=<0.0001
Gastric Acid · Human Experimentation
Primary: Change From Baseline in Median 24-hour Intragastric pH on the 7th Day of Drug Administration — 4.575; 3.980; 3.165; 2.550 pH scale
Orthomyxoviridae Infection · Influenza · Myxovirus Infection
Primary: Geometric Mean Titers (GMTs) of Hemagglutination Inhibition Antibody Titers Pre- and Post-vaccination With Fluzone® High Dose or Standard Fluzone® Vaccines. — 28.25…
Gastric Acid · Human Experimentation
Primary: Change From Baseline in Median 24-hour Intragastric pH on the 7th Day of Drug Administration — 3.250; 4.160; 2.180; 2.900 pH scale
Hypertension
Primary: Change From Baseline at 8 Weeks in Seated Trough Cuff Mean Diastolic Blood Pressure (DBP) (Observed Telmisartan Effect) — -13; -16.4; -16.2; -16.9 mmHg
Ankylosing Spondylitis
Primary: Number of Subjects With a Reduction in Signs and Symptoms as Measured by Assessments of Ankylosing Spondylitis (ASAS) 20 Response at Week 12 — 18; 12; 20; 32…
Benign Prostatic Hyperplasia
Primary: Adverse Events — 431; 188; 29; 0 participants
Asthma
Primary: PC20 AMP (Post-treatment Compared to Baseline) — 4.9; 5.2; 3.7; 3.0 Logarithm (mg/mL)
Infarction, Myocardial
Primary: Number of Participants With Complete Sum ST Resolution (STR) 60 Minutes (Min) After Percutaneous Coronary Intervention (PCI) (Per Protocol Population) — 71; 65…
Osteoarthritis, Knee · Pain
Primary: Change From Baseline of the Average Pain Intensity Based on an 11-point Numerical Rating Scale(NRS) Over the Last Week of the Maintenance Period at Week 12. — -3.0…
Arthralgia · Bunion · Hallux Valgus
Primary: Sum of Pain Intensity Difference Over 48 Hours (SPID48) — 54.1; 122.2; 143.7; 140.3 Scores on a scale — p=<0.001
Hyponatremia
Primary: Change in Serum Sodium From Baseline to the 48 Hour Assessment or Study Drug Discontinuation. — 126.03; 126.39; 125.55; 130.4 mEq/L — p=0.028
Parkinson Disease
Primary: Unified Parkinson's Disease (PD) Rating Scale (UPDRS) Total Activities of Daily Living Scores (Intent-to-Treat Population) — 9.4; 8.9; 8.2; 8.1 points on a scale
Attention Deficit/ Hyperactivity Disorder
Primary: Attention Deficit/Hyperactivity Disorder (ADHD) Symptoms Total Score of the Conners Adult ADHD Rating Scale (CAARS) — 36.5; 35.6; 37.3; 26.1 units on a scale — p=0.136