Phase 1 N=18 ONO-4538 Phase I Study in Patients With Solid Tumor
Advanced Solid Tumors · Recurrent Solid Tumors
Primary: PK Outcome: Cmax of ONO-4538 — 26.0; 64.3; 242.0 µg/mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=12 A Trial to Evaluate Safety, Tolerability and Efficacy of Elamipretide in Subjects With Barth Syndrome
Barth Syndrome
Primary: Part 1: Distance Walked During the 6-Minute Walk Test (6MWT) by Visit — 400.1; 412.6; 443.1; 443.9 meters
N/A N=24 Long-term Monitoring of Patients With Cardiac Amyloidosis With Implantable Event Monitors
TTR Cardiac Amyloidosis
Primary: Sudden Death — 0 Participants
N/A N=71 Single Shot Lumbar Erector Spinae Plane (ESP) Block in Total Hip Replacement (THR)
Total Hip Replacement · Analgesia
Primary: Post-operative Pain Score in Numeric Rating Scale (NRS) From 0 (no Pain) to 10 (Extreme Pain) — 3; 3 score on a scale
Phase 1 N=90 A First-in-Human Study of SBP-9330 in Healthy Subjects
Smoking Cessation
Primary: Number of Treatment-Emergent Adverse Events [Safety and Tolerability] — 0; 1; 1; 1 Participants
N/A N=33 Biotrue ONEday Contact Lenses With EPG03 Packaging Solution Compared to Biotrue ONEday Contact Lenses
Contact Lens Wearer
Primary: Normalized logMAR Visual Acuity — -0.01; -0.02 LogMAR
N/A N=379 Advisor HD Grid Observational Study
Persistent Atrial Fibrillation · Ventricular Tachycardia
Primary: Rate of Subjects With Acute Success — 287; 14 Participants
Phase 2 N=27 Effects of Tradipitant on Satiation, Gastric Volume, Gastric Accommodation, and Gastric Emptying in Healthy Volunteers
Healthy Volunteer
Primary: Fasting Gastric Volume as Measured by Single Photon Emission Computed Tomography (SPECT) — 178.8; 191.1 mL
N/A N=17 Clinical Evaluation of a Manufacturing Process for a Frequent Replacement Silicone Hydrogel Multifocal Contact Lens
Refractive Ametropia
Primary: Binocular Visual Acuity (VA) With Study Lenses at 4 Meters (logMAR) — -0.08; -0.06 logMAR
N/A N=9 Designing an Implementation Strategy for Lung Screening and Smoking Cessation Treatment in Community Health Centers
Smoking Cessation
Primary: Feasibility of Intervention Measure — 4 units on a scale
N/A N=50 Clinical Comparison of Two Soft Contact Lenses
Myopia
Primary: Subjective Overall Score — 80.2; 88.2 score on a scale
Phase 3 N=414 Evaluation of Efficacy and Safety of Iloperidone in the Acute Treatment of Manic or Mixed Episodes Associated With Bipolar I Disorder
Bipolar I Disorder
Primary: Change From Baseline to Week 4 in Young Mania Rating Scale (YMRS) Total Score — -14.0; -10.0 Change from Baseline in YMRS Total Score
N/A N=66 Impact of Decision Aids in Urogynecology
Pelvic Organ Prolapse · Stress Urinary Incontinence · Overactive Bladder
Primary: Patient Knowledge — 60; 72 percentage of questions answered correct — p=0.06
N/A N=39 An Exploratory Investigation of the Effects of Single Use vs. Reuse Catheters in Intermittent Catheterization
Urinary Incontinence
Primary: Change in Health-related Quality of Life From Baseline (Visit 1) to Termination (Visit 5), Measured by the Intermittent Self-Catheterization Questionnaire Index Score…
Phase 4 N=15 Buprenorphine Loading in the Emergency Department
Opioid-use Disorder
Primary: Number of Participants With Successful Rapid Induction — 14 Participants