Clinical Trial Search

Primary: Best Overall Response Rate (BORR) Within Brain of Previously Untreated Participants (Assessed by Independent Review Committee [IRC] Using Modified Response Evaluation…

Primary: Percent Change in Incontinent Episodes — -38.26; -15.29 percent change in incontinent episodes — p=0.02

Primary: Number of Participants Free of Live Head Lice and Free of Viable Eggs — 57; 55; 32; 46 Participants

Primary: Structured Clinical Interview for DSM-IV Axis I Disorders — 7.94; 8.20 percentage of participants

Primary: Best Overall PSA Response — 8; 20; 65 percentage of participatns

Primary: Minutes With Seizure on EEG — 165.2; 464.8 minutes with seizure

Primary: Change From Baseline in Fatigue at Day 43 — -1; -3 units on a scale — p=0.3

Primary: Progression-free Survival (PFS) — 8.7 months

Primary: The Number of Insulin-independent Subjects at Day 75 (± 5 Days) Following the First Islet Cell Transplantation — 4; 1 participants

Primary: Freedom From Recurrence of Atrial Fibrillation — 50 successful participants

Primary: Number of Gingival Bleeding Sites at 24 Weeks — 13.24; 24.90 Number of bleeding sites — p=<0.0001

Primary: Change From Baseline (Week 0) to Week 2 in Serum Phosphorus — 7.2; 7.2; 7.24; 6.34 mg/dL — p=0.001

Primary: Cumulative Incidence of Non Relapse Mortality (NRM) — 21 percentage of patients

Primary: Total Tic Severity Score (Part 2 Only) Crossover Analysis Over 6 Periods — 24.32; 25.41; 22.99 Total Tic Severity Score — p=0.0087

Primary: Incidence of Adrenal Cortical Adenomas — 3 Particpants