12,372 trials
Autistic Disorder
Primary: Mean Change (Week 8 - Baseline) in the Autistic Behavior Checklist (ABC) Irritability Subscale Score — -5.0; -12.9 units on a scale
Arthritis, Rheumatoid
Primary: Number of Subjects Experiencing Any Adverse Event — 76 participants
Pulmonary Arterial Hypertension, Children
Primary: Percent Change From Baseline in Peak Volume of Oxygen (VO2) Consumed : Intent To Treat Population — 6.44; 13.40; 10.58; 10.24 percent change — p=0.056
Cystic Fibrosis
Primary: Coefficient of Fat Absorption (%) — 88.62; 49.78 Percentage — p=<0.001
Familial Hypercholesterolemia
Primary: Percent Change in Low-density Lipoprotein Cholesterol (LDL-C) From Baseline (Day 0) to the End of the 12-week Double-blind Treatment Phase — -38.5; -44.4; -50.2; -0.5…
Hemophilia A
Primary: Number of Patients Who Achieved Hemostatic Efficacy After Surgery — 15; 3; 5; 2 patients
Computed Tomography · Diagnostic Imaging
Primary: The Quality of Visualization of the Contrast-Enhanced Computed Tomography (CECT) Images, Based on the Blinded Readers' Assessment. — 366; 17; 16; 3 Number of…
Asthma
Primary: The Time-weighted Average of Change in Forced Expiratory Volume in One Second (FEV1) — 0.09; 0.17; 0.01 Liter — p=0.022
Depressive Disorder, Major
Primary: Percentage of Participants With Depressive Recurrence After Time (t) in Days — 0.68; 2.11; 1.37; 2.11 percentage of participants — p=<0.001
Attention Deficit Hyperactivity Disorder · Attention Deficit Disorders With Hyperactivity · Attention Deficit Hyperactivity Disorders
Primary: Change in ADHD-RS-IV Total Score From Baseline at Up to One Year — -24.8 Units on a scale — p=< 0.0001
Depressive Disorder
Primary: Change From Baseline in the Hamilton Depression Scale (HAM-D 17 Items) Total Score — 19.8; 19.4; 14.7; 14.6 Score in scale — p=0.805
Gout
Primary: Percentage of Subjects Whose Last Three Serum Urate Levels Are <6.0 Milligram Per Deciliter (mg/dL). — 48; 65; 69; 22 Percentage of subjects — p=<0.001
Gout
Primary: Percentage of Subjects Whose Serum Urate Level is <6.0 Milligrams Per Deciliter (mg/dL) at the Final Visit. — 45.2; 67.1; 42.1 percentage of subjects — p=0.233
Prostatitis
Primary: Clinical Success — 46; 48; 52 Participants
HIV Infections
Primary: Number of Patients With Division of Acquired Immunodeficiency Syndrome (DAIDS) Grade 3 or 4 - Haemoglobin — 1; 2; 6 participants