17,261 trials
Graft vs Host Disease
Primary: Overall Response Rate (ORR) at Cycle 7 Day 1 — 36.4; 50.0; 28.6; 40.0 Percentage of participants
Locally Advanced Lung Carcinoma · Non-Small Cell Lung Carcinoma · Small Cell Lung Carcinoma
Primary: Number of Participants With Adverse Events That Are >= Grade 4 According to the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE)…
Lung Cancer · Lung Metastases
Primary: Number of Patients Who Are Free From Pulmonary Exacerbations — 72; 40 percental of participants
Enhanced Recovery After Surgery
Primary: Time to Gastrointestinal Recovery (GIR) — 32.6; 30.8; 33.4 hours — p=0.767
Colorectal Cancer
Primary: RXC004 Monotherapy (Arm A): Disease Control Rate (DCR) Using Each Patient's Best Overall Response (BOR) According to Response Evaluation Criteria in Solid Tumours…
Advanced Gastric Cancer
Primary: Objective Response Rate (ORR) — 1; 19; 9; 0 Participants
Fibromyalgia
Primary: Heart Rate Beats Per Minute (BPM) - First Dose (15 mg) — 76; 67; 67; 68 Heart beats per minute
Gastrointestinal Neoplasms · Adenocarcinoma
Primary: Phase 1b: Number of Participants With Adverse Events (AEs) — 3; 6; 5 Participants
Psychosis · Schizophrenia · Schizo Affective Disorder
Primary: Changes in Brain Redox State — -0.269; -0.485 ratio
Fatigue
Primary: Percentage Change in Self-reported Fatigue Visual Analog Scale (VAS) Scale — -21.0; -12.6 Percentage change
Norovirus Infections
Primary: Number of Participants With Solicited Symptoms of Reactogenicity (Gastrointestinal [GI] and Systemic) — 20; 20; 2; 9 Participants
Primary Aldosteronism · Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral)
Primary: Change in 24-hour Urinary Aldosterone Excretion Rate — 0.21 mcg/24h — p=0.96
Mild Cognitive Impairment · Mild Dementia · Moderate Dementia
Primary: Blood Biomarkers of Pharmacodynamic Response- Cytokines — 26.672; 190.829; 20.309; 2293.879 picogram/milliliter (pg/ml)
GLUT1DS1 · Epilepsy · Glut1 Deficiency Syndrome 1, Autosomal Recessive
Primary: Neuropsychological Score of Sustained Attention — 11 Participants
ADHD · Attention Deficit Disorder
Primary: Change in Adult Attention-Deficit/Hyperactivity Disorder (ADHD) Symptoms — 37.4; 37.3; 29.6; 29.0 units on a scale — p=0.7145