N/A N=72 Biological Response to Brief Psychological Challenge
Acute Inflammatory Response to Psychological Stress
Primary: Cell-free Mitochondrial DNA — 165.79; 405.56; 175.45; 164.45 Copies per uL — p=0.86
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=47 A Study of GFH018 in Patients With Advanced Solid Tumors
Advanced Solid Tumor
Primary: Incidence of Dose-limiting Toxicity (DLT) Events — 0; 0; 0; 0 Participants
N/A N=37 EHR Embedded Comparative Effectiveness Studies--CPS
Disk Herniated Lumbar
Primary: Compliance Rate With Assigned Treatment — 89; 50 percentage of eligible patients
Phase 2 N=50 A Phase 2a Study To Evaluate The Pharmacokinetics, Safety, Efficacy, Tolerability, And Pharmacodynamics of Sotatercept (ACE-011) for the Correction of Anemia in Subjects With End-stage Renal Disease on Hemodialysis.
Anemia
Primary: Observed Maximum Concentration (Cmax) — 1.022; 2.40; 3.66; 3.97 ug/mL
N/A N=61 The Effectiveness of TECH: Tablet Enhancement of Cognition and Health
Mild Cognitive Impairment
Primary: The Montreal Cognitive Assessment (MoCA) — 22.6; 22.3; 23.1; 21.9 units on a scale
Phase 2 N=24 Avalglucosidase Alfa Extension Study
Glycogen Storage Disease Type II Pompe Disease
Primary: Number of Participants With Treatment-Emergent Adverse Events (TEAEs), Treatment-Emergent Serious Adverse Events (TESAEs), Infusion Associated Reactions (IARs) and…
Phase 2 N=80 Phase 2a Study of HU6 in Subjects With Elevated Liver Fat and High BMI Volunteers
NASH - Nonalcoholic Steatohepatitis
Primary: Percentage of Change From Baseline in Liver Fat Content as Assessed by MRI-PDFF — -26.8; -35.6; -33.0; 5.4 percentage of change
N/A N=54 Digital Intervention To Improve Diet Quality
Diet, Healthy · Pregnancy Related
Primary: Intervention Engagement- Number of Text Messages Completed — 7.4 text messages
N/A N=14 Comparison of Two High-intensity Gait Training Interventions on Contraversive Pushing Behaviors in Individuals Poststroke
Stroke
Primary: Change in Scale for Contraversive Pushing — -47.01; -59.72 percent change in points
Phase 2 N=256 Study of AZD1222 for the Prevention of COVID-19 in Japan
COVID-19
Primary: Percentage of Participants With Seroresponse to the Spike (S) Antigen of AZD1222 as Measured by Meso Scale Discovery (MSD) Serology Assay — 100.0; 0.0; 100.0; 0.0…
Phase 1 N=32 PF-04634817 Renal Impairment Study
Renal Insufficiency
Primary: Area Under the Curve From Time Zero to 48 Hours[AUC (0 - 48)] — 1294; 1399; 2024; 2860 Nanogram*hour/milliliter (ng*h/mL)
Phase 2 N=7 A Clinical Trial of PRAX-944 in Participants With Essential Tremor
Essential Tremor
Primary: Part A: Change From Baseline in Essential Tremor Rating Assessment Scale (TETRAS) Upper Limb Score — -1.427; -2.912 Scores on a scale — p=0.1048
N/A N=1,054 A Retrospective Non-interventional Study of Breast Cancer Patients Diagnosed With HR+/HER2- Locally Advanced or Metastatic Breast Cancer Treated With Palbociclib in Denmark
Breast Cancer
Primary: Progression-Free Survival (PFS) for Participants Who Received Palbociclib in Combination With Aromatase Inhibitor (AI) — 27.4 Months
N/A N=100 Modified Reporting of Positive Urine Cultures Collected From Long Term Care
Urinary Tract Infections · Asymptomatic Bacteriuria
Primary: Proportion of Asymptomatic Bacteriuria Treated With Antibiotics and Urinary Tract Infection Treated With Antibiotics — 31; 25 Participants
N/A N=10 Development of a Community-based HCV Treatment Completion Intervention Among HCV Positive Homeless Adults
Hepatitis C Virus (HCV) Infection
Primary: Number of Participants Completing HCV Treatment — 3; 6 Participants