65,437 trials
Relapsed and/or Refractory Multiple Myeloma
Primary: Progression-Free Survival (PFS) — 4.79 Months
Biliary Tract Cancer (BTC) · Colorectal Cancer (CRC) · Endometrial Cancer
Primary: Phases 1 and 2: Number of Participants With Any Treatment-emergent Adverse Event (TEAE) — 8; 6; 13; 7 Participants
Depression · Anxiety
Primary: Positive Affect Subscale of the Positive and Negative Affect Scale (PANAS-P) — 20.76; 29.42; 24.18; 19.42 score on a scale — p=.002
Tachycardia
Primary: Number of Participants With Freedom From Magnetic Resonance Imaging (MRI) Scan Related Complications — 14; 14; 15; 12 Participants
Von Willebrand Diseases
Primary: Total Annualized Bleeding Rate (TABR) — 29.13 Bleeding events per year
Prostate Cancer · Mild Cognitive Impairment
Primary: PET Biomarker Uptake — 0.95; 0.98 Standard Uptake Measure SUV
Paroxysmal Atrial Fibrillation
Primary: Percentage of Participants With Freedom From Primary Safety Events at 12 Months Post-procedure (Acute and Chronic Events) Using the Boston Scientific Cardiac…
Relapsed/Refractory Multiple Myeloma
Primary: Number of Participants Reporting One or More Adverse Events (AEs) — 642 Participants
Metastatic Pancreatic Cancer
Primary: Number of Participants With Treatment-related Adverse Events as Assessed by CTCAE v4.0 (Phase 1 and 2) — 8; 38 Participants
Uveal Melanoma
Primary: Relapse Free Survival (RFS) Rate at 32 Months — 50 Probability
Physical Inactivity
Primary: Meaning Salience — 5.61 score on a scale
Lymphoma · Metastatic Malignant Solid Neoplasm · Metastatic Melanoma
Primary: Maximum Tolerated Dose (MTD))/Recommended Phase 2 Dose of Trigriluzole — 420 mg
Renal Cell Carcinoma
Primary: Number of Participants Categorized According to Eastern Cooperative Oncology Group Performance Status (ECOG-PS) — 29; 9; 3; 0 Participants
Covid19
Primary: Number of Participants With Impaired Swallowing Safety — 3; 1 Participants — p=<0.001
Adult Brain Glioblastoma · Glioblastoma Multiforme
Primary: Number of Participants Experiencing Regimen-limiting Toxicity (RLT) — 0; 0 Participants