Phase 2 N=16 A Study to Evaluate TRS01 Eye Drops in Participants With Active Non-infectious Anterior Uveitis
Non-infectious Anterior Uveitis
Primary: Assessment of Both Systemic and Ocular Adverse Events — 2; 5 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=32 Median Nerve Stimulation Pilot
Tourette Syndrome · Tic Disorders · Tic Disorder, Chronic Motor or Vocal
Primary: Change in Tic Frequency From When MNS is Turned Off — 12.1; 8.9 Tic frequency (number of tics in 40 s) — p=0.0104
Phase 1 N=12 Food Effect Study to Evaluate the Effect of High-Fat Meal on the Relative Bioavailability of PF-07321332 Boosted With Ritonavir in Healthy Adult Participants
Healthy Participants
Primary: Area Under the Plasma Concentration-Time Profile From Time Zero to the Time of the Last Quantifiable Concentration (AUClast) of PF-07321332 — 43360; 35860 Nanogram*hour…
N/A N=22 Faith-Based African American Cancer Survivorship Storytelling
Cancer
Primary: Hospital Anxiety and Depression Scale (HADS) Score — 3.86; 0.60; 3.40; 1.20 score on a scale
N/A N=109 Quit For Life (QFL): Smoking Cessation Among Chinese Smokers Living With HIV
Smoking Cessation · HIV Infections
Primary: Number of Participants With Biochemically Verified Smoking Cessation — 26; 10 Participants
N/A N=53 Piloting Pathways With Lung Cancer Patients
Metastatic Lung Cancer
Primary: Feasibility of Enrollment: Percentage of Eligible and Approached Patients Who Agree to Participate — 53 Participants
Phase 3 N=1,539 A Phase III Study to Assess the Lot-to-lot Consistency of GSK's Investigational RSV Maternal Vaccine and the Immune Response and Safety of RSV Maternal Vaccine When Given Alone or Co-administered With GSK's Influenza D-QIV Vaccine in Healthy Non-pregnant Women.
Respiratory Syncytial Virus Infections
Primary: Percentage of Participants Reporting Solicited Administration Site Events in RSV Pooled Group, RSV+Flu Pooled Group and Flu+Placebo Group — 53.6; 51.1; 34.4; 4.4…
Phase 4 N=45 Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery
Major Depressive Disorder · Surgery · Orthopedic Disorder
Primary: Montgomery-Asberg Depression Rating Scale (MADRS) Score — 17.0; 12.7; 16.4; 25.4 score on a scale — p=0.13
N/A N=23 Watermelon Focused Dietary Inflammatory Index Intervention
Inflammation · Diet Modification
Primary: Change in C-reactive Protein — -0.04; -0.56 mg/L
Phase 3 N=2,797 Safety of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers
Healthy Volunteers (Meningococcal Infection)
Primary: Number of Participants With Immediate Unsolicited Systemic Adverse Events (AEs) — 7; 2 Participants
Phase 3 N=235 MT10109L in the Treatment of Lateral Canthal Lines
Lateral Canthal Lines
Primary: The Percentage of Participants With a ≥ 2-grade Improvement From Baseline on the Facial Wrinkle Scale With Photonumeric Guide (FWS) According to INVESTIGATOR AND…
Phase 2 N=159 Chronic Pain Master Protocol (CPMP): A Study of LY3526318 in Participants With Chronic Low Back Pain
Chronic Low-back Pain
Primary: Change From Baseline for Average Pain Intensity as Measured by the Numeric Rating Scale (NRS) at Week 4 — -1.28; -0.90 score on a scale
N/A N=72 PREDICT: A PBRN Feasibility Study on COVID-19 Screening in Dental Practice
COVID-19 Infection
Primary: Perception of Safety — 60; 74; 51; 52.5 score on a scale
Phase 2 N=15 Sarilumab in Patients With Glucocorticoid-Dependent Sarcoidosis
Sarcoidosis
Primary: Number of Participants Without Sarcoidosis Flare (Flare-Free Survival) — 2; 7 Participants
Phase 2 N=15 Cannabidiol on Reward- and Stress-related Neurocognitive Processes in Individuals With Opioid Use Disorder
Opioid-use Disorder
Primary: Change in Cue-reactivity — 0.7; 1.1; 0.9; 2.4 score on a scale