Phase 4 N=5 Simvastatin for mTBI
TBI-Traumatic Brain Injury
Primary: Cerebrospinal Fluid (CSF) T-tau Concentration — 24; 33.5 pg/ml
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=2 Tissue Sealant Use in LASIK Enhancement Surgery
Epithelial Ingrowth
Primary: Slit Lamp Examination for Presence of Epithelial Ingrowth Under LASIK Flap — 0 Eyes
Phase 4 N=84 Bromocriptine-QR Therapy on Sympathetic Tone and Vascular Biology in Type 2 Diabetes Subjects
Diabetic Autonomic Neuropathy
Primary: Change in E/I Ratio From Baseline to Endpoint After 24 Weeks of Intervention With Bromocriptine QR vs Placebo — -0.02; -0.05 E/I ratio change — p=0.603
Phase 4 N=714 Assessment In a Real World Setting of the Effect of Inhaled Steroid-based Triple Therapy Versus the Combination of Tiotropium and Olodaterol on Reducing Chronic Obstructive Pulmonary Disease (COPD) Exacerbations [AIRWISE]
Pulmonary Disease, Chronic Obstructive
Primary: Time to First Moderate or Severe Chronic Obstructive Pulmonary Disease (COPD) Exacerbation Over the 12 Month Study Period — NA; NA Months
Phase 4 N=65 Empagliflozin Impact on Hemodynamics in Patients With Heart Failure
Heart Failure
Primary: Change in Pulmonary Artery Diastolic Pressure From Baseline to End of Treatment Period (Defined as Average of Pulmonary Artery Diastolic Pressure Measurements Between…
Phase 4 N=18 Treatment of Heavy Menstrual Bleeding in Women With Uterine Fibroids
Heavy Menstrual Bleeding · Menorrhagia · Uterine Fibroids
Primary: Change in Self-Reported Menorrhagia Scores — 59.1; 25.4 score on a scale — p=0.11
Phase 4 N=120 Transverse Abdominis Plane (TAP) Block After Cesarean Delivery
Postoperative Pain · Pregnancy · Obesity
Primary: Morphine Equivalents 0-24 Hours (Mgs) — 54; 38; 32; 45 Morphine equivalents (mg) — p=.05
Phase 4 N=20 Fycompa Titration Intervals and Effects on Retention Rate
Epilepsy
Primary: The Percentage of Subjects Completing 52 Weeks of Adjunctive Therapy During the Maintenance Phase [Retention Rate]. — 2; 3 Participants
Phase 4 N=40 Genomics and Epigenomics of the Elderly Response to Pneumococcal Vaccines
Pneumonia · Aging
Primary: Pneumococcal-specific Antibody Responses — 72.1; 79.4; 128.9; 120.9 log2 titer
Phase 4 N=105 Insulin for Hyperglycemia in Stroke Trial
Hyperglycemia · Stroke, Acute
Primary: Glycemic Control — 10.7; 10.9 mmol/L — p=0.677
Phase 4 N=365 EntrestoTM (LCZ696) In Advanced Heart Failure (LIFE Study)
Heart Failure
Primary: Change in NT-proBNP — 0.14; 0.19 unitless — p=0.45
Phase 4 N=39 Smartphone Intervention for Smoking Cessation and Improving Adherence to Treatment Among HIV Patients
Smoking · Smoking Cessation · HIV
Primary: Number of Participants With Smoking Cessation — 3; 5; 7 Participants
Phase 4 N=3 Use of Patiromer to Transition Chronic Kidney Disease Patients With Hyperkalemia to a Plant-rich Diet.
Chronic Kidney Diseases · Hyperkalemia
Primary: Change in Fasting Serum Potassium Concentrations — -0.2 mg/dL
Phase 4 N=263 Dapagliflozin Effect on Symptoms and Biomarkers in Patients With Heart Failure
Chronic Heart Failure With Reduced Systolic Function
Primary: Difference in the Average of the 6- and 12-week Mean N-terminal Pro B-type Natriuretic Peptide (NTproBNP). — 1133; 1191 pg/dL
Phase 4 N=413 Comparison of Three Licensed Influenza Vaccines
Influenza
Primary: Mean Change of HAI Serum Antibody Titers to A/California/07/09 (H1N1) — 1937; 383; 607 titer