Phase 4 N=60 Cognitive vs. Emotional Psychopharmacological Manipulations of Fear vs. Anxiety
Anxiety Disorder
Primary: Magnitude of Startle Reflex During Safe Condition — 42.2880893; 42.39801; 43.61243; 44.1886408 millivolts (mV)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=47 TMS Augmented Exposure Therapy
Phobia
Primary: Subjective Anxiety Symptoms — 17.4; 7.3 units on a scale — p=0.025
N/A N=918 Expectation of Unpleasant Events in Anxiety Disorders
Anxiety Disorders
Primary: Change in Percent of Correct Button Presses During Threat Compared to the Safe Condition (AAST) — -0.016; 0.008 Percentage of accurate responses
N/A N=59 A Single-Session Intervention for Families on Waitlists for Child Anxiety Treatment
Anxiety Disorders
Primary: Screen for Child Anxiety Related Emotional Disorders - Parent Version at Posttreatment — 35; 30 units on a scale
Phase 2 N=89 Fast-Fail Trials in Mood and Anxiety Spectrum Disorders; Kappa Opioid Receptor Phase 2a
ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)
Primary: Change in Ventral Striatal Activation Occurring in Anticipation of Reward During the Monetary Incentive Delay Task Measured by fMRI — 0.718; 0.331 Z score — p=0.0095
Phase 2 N=15 Antiglucocorticoid Therapy for Cognitive Impairment in Late-life Anxiety Disorders
Anxiety Disorders
Primary: Drug Acceptability, as Measured by Number of Participants With Dose-limiting Side Effects — 1 Participants
N/A N=29 Pilot Study of Cognitive Behavioral Therapy for Anxiety and Bipolar I Disorder
Bipolar Disorder · Anxiety Disorders
Primary: Reductions Over Time in Anxiety Symptoms as Measured by Hamilton Anxiety Rating Scale — 14; 18.81; 11.78; 17.70 Units on scale — p=.02
Phase 4 N=90 Acamprosate in Alcoholics With Comorbid Anxiety or Depression
Alcohol Dependence · Major Depression · Social Anxiety Disorder
Primary: Percent Days Drinking — 34.9; 31.9 percentage of days drinking — p=0.64
N/A N=63 Digital Intervention to Treat Anxiety and Depression Among Persons Receiving Treatment for Opioid Use Disorder
Opioid-use Disorder · Anxiety Disorders · Depressive Disorder
Primary: Change in Anxiety Symptoms as Assessed by Generalized Anxiety Disorder- Q-IV Scale — -1.8; -1.04; -2.47; -1.53 units on a scale — p=.755
N/A N=64 Early Intervention for Children at Risk for Anxiety
Anxiety Disorder
Primary: Number of Responders Based on Clinician Global Impression-Anxiety Improvement — 20; 9 Participants — p=<.05
Phase 2 N=33 Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Primary: Pediatric Anxiety Rating Scale. — 11.62; 14.04 units on a scale — p=.04
Phase 3 N=45 Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Autism · Asperger's Syndrome · Generalized Anxiety Disorder
Primary: Pediatric Anxiety Rating Scale (Measures the Severity of Anxiety Symptoms) — 16.33; 17.62; 11.58; 16.05 units on a scale
Phase 2 N=70 Corticotropin-Releasing Hormone Receptor 1 (CRH1) Antagonism in Anxious Alcoholics^
Alcohol-Related Disorders · Alcohol Dependence · Alcoholism
Primary: Alcohol Craving in Response to the Alcohol Cue Script — 12.7; 10.7 Units on a scale
N/A N=89 Comparing Virtual Reality (VR) to Non-VR for Decreasing Preoperative/Procedural Anxiety
Preoperative Anxiety
Primary: Preoperative Anxiety Score in Pediatric Oncology Patients — 31.44; 28.26; 45.38; 32.81 score on a scale
Phase 4 N=183 A Collaborative Care Program to Improve Treatment of Depression and Anxiety Disorders in Cardiac Patients
Depression · Generalized Anxiety Disorder · Panic Disorder
Primary: Change in Mental Health-related Quality of Life From Baseline to 24 Weeks — 8.87; 8.39 units on a scale — p=0.002