Clinical Trial Search

Primary: Change From Baseline in Positive and Negative Syndrome Scale (PANSS) Total Score at Week 4 — -23.9; -22.8; -17.5 units on a scale — p=<0.001

Primary: Change From Baseline to Week 6 in PANSS Total Score — -15.9; -20.0; -24.0 units on a scale — p=0.0560

Primary: Mean Change From Baseline to Week 6 in Positive and Negative Syndrome Scale (PANSS) Total Score. — -3.32; -4.35; -5.58; -3.48 Units on a scale — p=0.0093

Primary: Change From Baseline in Positive and Negative Syndrome Scale (PANSS) Total Score at Week 4 — -9.7; -17.2 Units on a scale — p=0.001

Primary: Mean Change From Baseline to Endpoint in Positive and Negative Syndrome Scale (PANSS) Total Score. — -8.9; -5.0; -15.2; -8.3 Units on a scale — p=0.0005

Primary: Change From Baseline in Positive and Negative Syndrome Scale (PANSS) Total Score at Week 4 — 98.1; 97.7; 97.4; 97.2 units on a scale — p=0.2053

Primary: Loss of Effect Over Time — 7; 15; 6; 3 Participants

Primary: Time to Relapse or an Impending Relapse — 0; 3; 1; 14 relapses

Primary: Mean Heinrichs-Carpenter Quality of Life Scale Scores Over Time — 51.25; 55.13; 59.15; 60.08 score on a scale — p=0.0145

Primary: The Change From Baseline at Day 85 in Positive and Negative Syndrome Scale (PANSS) Total Score — -20.9; -21.8; -9.8 units on a scale — p=<0.001

Primary: Change in the Positive and Negative Syndrome Scale (PANSS) Total Score at Week 6 — -10.4; -13.8; -14.0; -20.2 units on a scale

Primary: Change From Baseline to Week 4 in the PANSS Total Score — -14.28; -13.95; -16.08; -9.27 score on a scale — p=0.0009

Primary: Change From Baseline to Week 6 in Positive and Negative Syndrome Scale (PANSS) Total Score — -22.9; -19.4 Units on a scale — p=<0.0001

Primary: Percentage of Participants Assessed as Very Much Improved or Much Improved Based on Clinical Global Impression-Improvement (CGI-I) Scale - Intent-to-treat (ITT)…

Primary: Number of Participants Demonstrating Improvement in Substance Use — 3; 3 participants

Primary: Least Squares Mean (LSM) Change From Baseline in the Positive and Negative Syndrome Scale (PANSS) Total Score at Week 4 — -14.6; -17.2; -10.0 Score on a Scale — p=0.440

Primary: Change in Positive and Negative Syndrome Scale (PANSS) - Total Score - Study Phases 1 and 2 — 83.6; 79.8; 77.6; 76.7 units on a scale — p=0.57

Primary: Change From Baseline in the Positive and Negative Symptom Scale (PANSS) Total Score at Week 6 — -14.08; -19.54 score on a scale — p=0.115

Primary: Mean Change From Baseline in the Positive and Negative Syndrome Scale (PANSS) at Week 4 — -13.3; -17.0; -12.7 Units on a scale — p=0.8590

Primary: Number of Subjects With an Adverse Events in a One Year Open Label Lurasidone Study — 59 participants

Primary: Changes From Study Period II Baseline (Week 0) to Weeks 3, 4, 6, 8, and 12 in Positive and Negative Syndrome Scale (PANSS) Total Score in Early Onset Response and Not…

Primary: Change From Baseline to Day 28 in Positive and Negative Syndrome Scale (PANSS) Total Score — -13.2; -8.3; -7.4; -13.4 score on a scale — p=0.017

Primary: Change From Baseline in PANSS Total Score at Week 6 — -19.3; -16.9; -19.6 score on a scale — p=0.886

Primary: Change From Baseline to the End of the Double-blind Treatment in the BPRS (Brief Psychiatric Rating Scale) Total Score — -8.9; -4.2 units on a scale — p=<0.05

Primary: Change From Baseline to Week 6 in Positive and Negative Syndrome Scale (PANSS) Total Score (Double Blind Phase) — -9.76; -18.73; -16.19; -18.25 Units on a scale — p=0.2846

Primary: Change From Baseline in Positive and Negative Syndrome Scale (PANSS) - Total Score at Week 13 — 88.98; 22.468 units on a scale

Primary: Biomarkers — 287.37; 340.83; 492.33; 420.17 pg/mL

Primary: Change From Baseline in PANSS Total Score at Day 42 — -17.4; -21.7; -21.6; -16.2 score on a scale — p=0.6043

Primary: Mean Change From Baseline in the Positive and Negative Syndrome Scale (PANSS) Total Score at Week 4 — 99.38; 98.54; 100.53; 100.03 Units on a scale — p=0.849

Primary: Maximum 3-Day Moving Average (MA) of the Discontinuation Symptom Checklist-Modified Rickels Total Score — 13.23; 11.50 units on a scale — p=0.170