Clinical Trial Search

Primary: Change From Baseline in American Spinal Injury (ASIA) Upper Extremities Motor Score — 15.58; 12.63 Scores on a scale — p=0.55

Primary: Total Spinal Cord Independence Measure, Version III (SCIM III) Score Following Treatment With SUN13837 Injection or Placebo in Adult With Acute Spinal Cord Injury…

Primary: Feasibility of Intraoperative Contrast-enhanced Ultrasound in Acute Traumatic Spinal Cord Injury - Number of Participants With Successful Intraoperative…

Primary: Muscle Mass Via Dual-Energy X-ray Absortiometry (DEXA)Scan Data — 6104.45; 6355.3 grams — p=.318

Primary: Gait Speed With 10-Meter Walk Test — -10.24; -1.79 seconds — p=0.006

Primary: Graded and Redefined Assessment of Strength, Sensibility and Prehension Test (GRASSP Test) — 4.5; 19.4 score change before and after — p=<0.000

Primary: Effect of Exercise on Inflammation (C-reactive Protein) — 0.00; 0.05 mg/dL

Primary: Percent Change in Hmax — 27.85; 8.43; -4.91; 16.20 percent change in Hmax

Primary: Number of Adverse Events Within 1 Year (365 Days) That Are Related to AST-OPC1 Injection — 92; 122; 133; 118 Adverse Events

Primary: Bone Mineral Density (BMD) at the Distal Femur and Proximal Tibia at Baseline and Month 12. — 1.102; 1.134; 0.898; 1.038 g/cm2

Primary: Physical Activity Level at Week 8 — 383; 297 Minutes per week

Primary: Change From Baseline in Exercise Capacity at 6 Months — 14.6; 18.5; 17.1; 13.9 ml/kg/min

Primary: Change in 6 Minute Walk Test — 19.57; 12.28; 9.63; 19.03 meters (m)

Primary: Change in Areal Bone Mineral Density at Hip — 0.92; -12.0; 1.19; -12.9 percentage change

Primary: Incidence of Treatment-emergent Adverse Events (AEs) and Serious Adverse Events (SAEs) — 5; 4; 5; 6 Participants

Primary: Physiology Measurements Before and After rTMS/Sham rTMS Protocol- Changes in Amplitude of Motor Evoked Potential (MEP) From TMS — 0.31; 0.43; 0.45; 0.65 millivolts (mV)

Primary: Change in Spinal Cord Independence Measure (SCIM) Version III Scores — 18.6; 27.0; 54.5; 50.0 score on a scale — p=<0.01

Primary: 10-meter Walking Speed (m/Sec) — 0.165; 0.215; 0.13; 0.13 speed (m/sec)

Primary: Percent Change in Bone Mass Density (BMD) in the Hip — -2.21; -12.82 percent change in bone mass density — p=0.05

Primary: Change in Maximal Inspiratory Pressure — 8.2; -3.0 cmH2O — p=<0.05

Primary: Electromyography — 0.00017507; 0.00006740 volts

Primary: Change in Motor Evoked Potential (MEP) Amplitude in the Tibialis Anterior Muscle at the End of Training. — -1.75; -2.01 Amplitude percentage of Mmax

Primary: Mean Arterial Blood Pressure in Response to Epidural Stimulation — 112.5 mmHg

Primary: Seated Systolic Blood Pressure — 86; 100.4; 102.7; 101.3 mmHg

Primary: Muscle Weakness — 2; 3 Participants

Primary: Systolic Blood Pressure — 116.3; 98.0 mmHg

Primary: Arm and Hand Function as Assessed by Score on the Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP) — 64.9; 58.3 score on a scale

Primary: Double-blind Change From Baseline in Ashworth Score Evaluating Spasticity — -0.19; -0.15 units on a scale

Primary: Affected Therapy Sessions — 16.4; 10.9 percentage of sessions

Primary: Dual Energy X-ray Absorptiometry (DXA) Assessment of Lean Tissue Mass (LTM) — 53.1; 50.5 kilograms — p=<0.01