Clinical Trial Search

Primary: Adult ADHD Investigator Symptom Rating Scale (AISRS) Score at End of Placebo Lead-In — 37.2 score on a scale

Primary: Change From Baseline at Week 4 in ADHD Symptoms Measured With the ADHD Rating Scale Version IV With Adult Prompts (ADHD RS IV) — -12.38; -13.88; -9.7 units on a scale…

Primary: Change From Baseline in Severity of Attention Deficit Hyperactivity (ADHD) Symptoms — -11.1; -18.2; -18.1 score on a scale

Primary: Post-treatment ADHD Symptoms — 14.46; 19.19 units on a scale of symptom severity — p=<.03

Primary: Dyadic Parent-Child Interaction Coding System (DPICS) - Behavior Counts — 67.2; 42.1; 53.8; 40.1 behaviors

Primary: Change in Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) Attention-deficit/Hyperactivity Disorder (ADHD) Checklist — 18.61; 18.19 units on a…

Primary: Change From Baseline in Adult Attention Deficit Hyperactivity Disorder (ADHD) Self-Report Scale (ASRS) Total Score at Week 4 — 52.6; -10.9 Unit on a scale

Primary: Inattention Subscale — -13.71; -16.18 units on a scale

Primary: Adult ADHD Investigator Symptom Rating Scale (AISRS) — 37.0; 15.0 units on a scale

Primary: Change in Adult ADHD Investigator Symptom Rating Scale Score — 17.3 units on a scale

Primary: Attention Deficit Hyperactivity Disorder Total Symptom Score — 21.4; 30.0; 20.2; 29.7 units on a scale — p=<0.05

Primary: Mean Change in the Conners' Adult ADHD Rating Scale-Investigator Rated: Screening Version (CAARS-Inv:SV) Total ADHD Symptom Score From Baseline to 12 Week Endpoint…

Primary: Adult Attention Deficit Hyperactivity Disorder (ADHD) Investigator Symptom Rating Scale (AISRS) Total Score — -7.6; -2.1 score on a scale — p==.0106

Primary: Change From Baseline in Total AISRS Score at the End of Double-blind Treatment (Week 8) — -17; -17 units on a scale

Primary: Change in ADHD-IV Rating Scale Total Score — -13.2; -5.8 units on a scale

Primary: Change From Baseline to 24 Weeks in the Conners' Adult Attention Deficit Hyperactivity Disorder Rating Scale - Investigator Rated: Screening Version (CAARS-Inv:SV) Total…

Primary: Change From Baseline in Conners' Adult ADHD Rating Scales-Observer: Screening Version (CAARS-O:SV) 18-item ADHD Symptoms Total Score at Day 56 — 40.71; 41.59; 40.51…

Primary: the Adult ADHD Rating Scale (AARS) (30% Reduction) — 50 percent of participants

Primary: Conners Scale — 36.64; 42.31; 40.08; 36.82 units on a scale — p=0.05

Primary: Change From Baseline in the Conners' Adult Attention-Deficit/Hyperactivity Disorder Rating Scale-Investigator Rated: Screening Version (CAARS-Inv:SV) 18-Item Total…

Primary: Number of Children Diagnosed With ADHD With Structured Diagnostic Assessment — 34; 16 number of kids

Primary: ADHD Severity — -20.6; -21.8 units on a scale

Primary: Mean Conners' Teacher ADHD Index T Score by Dose — 72.8; 63.1; 63.6; 61.5 Units on a scale (T-scores) — p==.001

Primary: Number of Participants With Adverse Events, Serious Adverse Events and Deaths. — 208; 2; 0 participants

Primary: ADHD Symptoms — 71.2; 78.4; 47.4; 55.5 Percent of item endorsement — p=<0.025

Primary: ADHD Rating Scale-IV-Parent Version: Investigator Scored - Total Score — 40.7; 38.6; 32.3; 37.3 units on a scale — p=<0.001

Primary: Lean Squares Mean (± Standard Error) of Math Test Score Over All Post-dose Time Points (0.5, 1, 2, 4, 8, 10, 12, 13, and 14 Hours Post-dose) Assessed During the…

Primary: Attention Deficit / Hyperactivity Disorder Total Sum Score of All 18 ADHD Symptom Items — 26.54; 25; 18.94; 18.46 Score

Primary: Discontinuations Due to Adverse Events (AE) — 1; 1 participants

Primary: The Effects of ADHD Medication Versus Placebo on Cotinine Levels — 180.7; 274.0 ng/ml — p=<0.05