N/A N=4,549 Longitudinal Study of Weight Change Following Lower Limb Amputation
Amputation Wound · Traumatic Amputation of Toe · Dysvascular Amputation of Lower Limb
Primary: % Weight Change From Baseline — 5.5; 0.9 % weight change
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Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=50 Forensic-medical Aspects of Lower Limb Prosthetics: An Observational Study
Amputation
Primary: Questionnaire: Trinity Amputation Prosthesis Experience Scale (TAPES) — 57; 8; 40 units on a scale
N/A N=15 Weight Loss Intervention for Individuals With Lower Extremity Amputation
Lower Extremity Amputation
Primary: Number of Individuals That Were Randomized of Those Contacted (Feasibility) — 15 participants
N/A N=147 Self-management to Improve Function Following Amputation
Amputation, Limb Loss
Primary: Short Musculoskeletal Function Assessment (SMFA) — 32.34; 30.19 score on a scale
N/A N=23 Falls in Older Persons With Limb Loss
Amputation · Elderly
Primary: Foot's Height During the Swing Phase of Walking (i.e., Foot Clearance) Measured in Centimeter — 6.1; 5.5; 6.1; 5.7 cm
N/A N=20 Upper Limb Loss Perturbation Response
Amputation
Primary: Whole-body Angular Momentum in Sagittal-plane; Momentum of the Body in the Sagittal Plane of Walking Progression — 0.025; 0.031; 0.027; 0.028 Unitless (normalized)
N/A N=30 Investigating Outcomes of Lower Limb Trauma
Trauma
Primary: Functional Outcome (Consisting of Questionnaire Score, Hamlyn Mobility Score (HMS) Gait/Activities of Daily Living Parameters) — 19.7; 58.2 units on a scale
Early Phase 1 N=33 N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes
Diabetes Mellitus · Critical Limb Ischemia · Lower Limb Amputation Knee
Primary: Change in Postoperative Laser-Assisted Fluorescent Angiography (LAFA) Perfusion. — 0.060; 0.096; 0.045; 0.031 percentage of defect
N/A N=4 Epidural Spinal Cord Stimulation for Sensory Restoration and Phantom Limb Pain in Upper-Limb Amputees
Phantom Limb
Primary: Stimulation Thresholds to a Variety of Stimulus Parameters — 2.13 milliamps
N/A N=10 AMP30: Autologous Fat Grafting, Amputation Sites Pain: Randomized
Wounded Warrior · Limb Shortening · Amputation
Primary: Efficacy of Autologous Fat Transfer at Pain Modulation at Respective Amputation Sites — 1.3; 0 score on a scale
N/A N=14 Agonist-Antagonist Myoneural Interface for Functional Limb Restoration After Transtibial Amputation
Amputation
Primary: Stability of Joint Position Control in Free Space — 4; 3.1 Distinct synergy activations
N/A N=18 Evidence Based Amputee Rehabilitation (EBAR) Program
Amputation Stumps · Diabetes Mellitus
Primary: Amputee Mobility Predictor — 36.4; 35.3; 41.7; 35.6 Points
N/A N=144 Cryoanalgesia to Treat Post-Amputation Phantom Limb Pain: A Department of Defense Funded Multicenter Study
Post-Amputation Phantom Limb Pain
Primary: Change From Baseline in Average Daily Phantom Pain Intensity — 0.5; 0 score on a scale
N/A N=16 Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Phantom Limb Pain · Postoperative Pain · Neuroma
Primary: Average Phantom Limb Pain (PLP) Score — 4.1; 3.1; 2.2; 3.0 score on a scale
Phase 4 N=16 Pathophysiology of Post Amputation Pain
Amputation Stumps · Neuroma
Primary: Change in Pain — -0.3; -2; -1; 1.3 units on a scale
Phase 4 N=144 Treating Phantom Limb Pain Using Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study
Phantom Limb Pain
Primary: "Average" Phantom Limb Pain Intensity 4 Weeks Following Initiation of an Ambulatory Continuous Peripheral Nerve Block (as Measured by the Numeric Rating Scale Within the…
N/A N=12 Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation
Amputation, Surgical · Amputation, Traumatic · Phantom Limb Pain
Primary: Average Pain Intensity Change From Baseline 1 Month Post-intervention — 0; 0; 0 score on a scale
N/A N=15 ICG Fluorescence Imaging in Lower Extremity Amputation Patients
Trauma Injury
Primary: Total Bone Blood Flow (TBBF)-Post Osteotomy — 4.9 mL/min/100g
N/A N=104 Auto Control of Volume Management for Limb Loss
Lower Limb Amputation Below Knee (Injury)
Primary: Change in Limb Volume — 8; 2 Participants
N/A N=44 Strength, Pain and Function in Operation Iraqi Freedom/Operation Enduring Freedom Amputees: A Nurse-Managed Program
Traumatic Amputation
Primary: Lower Extremity Muscle Strength- Extension — 24.5; 26.4; 27.6; 34.1 Kilograms — p=<0.05
N/A N=272 Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation Wound Complications
Amputation · Amputation; Postoperative, Sequelae · Wound Dehiscence
Primary: Overall Rate of Wound Complications — 26; 31 Participants
N/A N=131 Crossing the Divide: Piloting Integrated Care to Reduce Amputations Among Rural Patients With Diabetic Foot Ulcers
Diabetic Foot · Diabetic Ulcer of Left Foot · Diabetic Ulcer of Right Foot
Primary: Proportion of Patients Receiving Guideline-concordant Vascular and Infectious Disease Care Processes — 14; 6 Participants
N/A N=35 Assessment of Disability Compensation With the C-LEG COMPACT 2 Knee (Ref. 3C60 et 3C60=ST)
Amputation of Hip and Thigh, Level Unspecified
Primary: Timed Get Up and Go (TGUG) — 24.8; 21.6 seconds
N/A N=31 Physical Activity Behavior Change for Older Adults After Dysvascular Amputation
Amputation · Diabetes Mellitus, Type 2 · Peripheral Artery Disease
Primary: Retention Rate — 14; 13 Participants
Phase 1 N=6 Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA)
Peripheral Artery Disease · Vascular Disease · Critical Limb Ischemia
Primary: Number of Participants With Treatment-related Adverse Events Occurring During the Enrollment Period as Assessed by the Investigator Using the CTCAE 4.0 Scale. — 2; 0…
N/A N=10 Functional Outcomes in Dysvascular Transfemoral Amputees
Transfemoral Amputation · Unilateral Traumatic Amputation of Leg at or Above Knee
Primary: Change in Community Physical Activity as Measured by GPS — 1749; 1625; 1257 Steps per day
N/A N=16,746 This Study Combines Data From 3 Other Studies Testing Empagliflozin in Patients With Diabetes or With Chronic Heart Failure. The Study Looks at the Numbers of Patients Who Had Lower Limb Amputations
Diabetes Mellitus, Type 2
Primary: Incidence Rate of Lower Limb Amputation (LLA) — 0.40; 0.48; 0.27; 0.23 Patients with events per 100pt-yrs — p=0.9276
N/A N=6 Limb Health and Socket Pressure in Response to Powered Ankle Protheses
Pressure Ulcer, Ankle · Prosthesis User · Prosthesis Durability
Primary: Powered Transtibial Prosthesis on Socket Pressure — 0.58; 0.25 kPa/kg — p=0.009
N/A N=68 Bioimpedance as a Diagnostic Tool for Assessing the Need for Socket Modification in Transtibial Amputees
Transtibial Amputee
Primary: Number of Participants With Significant Increases in Socket Comfort Score (SCS) — 5; 6; 4 participants
N/A N=20 Evaluating Mobility Interventions in the Real World
Lower Limb Amputation · Drop Foot
Primary: Minimum Foot Clearance With Different Prostheses — 0.02117; 0.01976; 0.01932; 0.03055 meters