Clinical Trial Search

Primary: Change From Baseline of Surgical Site Pain Level (NRS) at Rest [Percentage of Baseline Pain] — 64; 100; 55; 69 percentage of baseline

Primary: AVERAGE Pain Measured With the Numeric Rating Scale First 5 Postoperative Days — 1; 3 units on a scale

Primary: Average Daily Pain Intensity 1st Week — 2 units on a scale

Primary: Average Phantom Limb Pain (PLP) Score — 4.1; 3.1; 2.2; 3.0 score on a scale

Primary: Opioid Consumption During First Postoperative Week — 5.0; 47.5 mg

Primary: AVERAGE Pain Measured With the Numeric Rating Scale — 2.4; 2.6 score on a scale

Primary: Proportion of Subjects With 50% or Greater Reduction in Overall Pain Intensity From Baseline — 32; 41 Participants

Primary: Total Narcotic Consumption During Hospital Stay — 90.79; 90.30 Oral Morphine Equivalents per day (OME) — p=0.97

Primary: Opioid Consumption — 24; 38; 24; 27 oral morphine mg equivalents (OME)

Primary: Change in Visual Analog Scale (VAS) Score From Baseline to 2 Week Post Initial Fitting. — 35 participants with > 50% VAS improvement

Primary: Total Narcotic Dose in Milligram Morphine Equivalents (MME) Per Kilogram — 0.035; 0.008 MME per kg

Primary: Change in Average RESIDUAL Limb Pain Scores Between Baseline and Day 28 of the Initial Treatment as Measured With the Numeric Rating Scale — 2.5; 0 score on a scale

Primary: Opioid Consumption — 31 milligrams of oxycodone

Primary: Pain Measured With the Numeric Rating Scale — 28; 34 units on a scale

Primary: Comparing Visual Analogue Scale (VAS) — 9.3; 8.6; 5.7; 4.9 score on a scale — p=0.112

Primary: Median Cumulative Morphine Equivalent — 0; 2.5; 0; 5 Morphine Equivalents

Primary: Post-operative Opioid Pain Medication Dose — 26.99; 31.12; 28.65; 33.15 mg of morphine equivalent dose (MED)

Primary: Visual Aanalog Scale (VAS) for Pain Assessment With Cough at 48 Hours — 1.7; 3.9 units on a scale — p=.0022

Primary: Patient Controlled Analgesia (PCA) Hydromorphone Usage — 44; 39 mL

Primary: Postoperative Fentanyl — 4.51; 6.14 microgram/kilogram

Primary: Average Knee Pain While Walking — 3.8 Scores on a scale

Primary: Time Until Patient is Ready for Discharge — 2.4; 2.3 days

Primary: Visual Analog Pain Scale — 2.29; 6.31 units on a scale

Primary: Percentage of Implanted Patients (de Novo Implants) With an Improvement of at Least 50% of the Overall Average Pain Over the Last 8 Days, Evaluated by Numerical Scale at…

Primary: Area Under the Curve (AUC) Pain Score - Based on Patient-reported Dynamic Numerical Rating Scale (NRS) Pain Scores — 6.39; 4.22 scores on a scale*hour

Primary: Total Fentanyl/Equivalent Day 0-1 — 23.6; 22.4 mcg/kg/day

Primary: Pain Disability Index Score (PDI) at Six Months Following Surgical Procedure — 26; 30; 12; 13 units on a scale — p=0.28

Primary: Pain Scores (Verbal Numerical Rating Scale;VNRS) During Postoperative Hours. — 7; 5; 6; 5 Units on a scale

Primary: Visual Analog Scale Pain Score — 45; 61 mm

Primary: Opioid Consumption POD 1 — 86.6; 90.5 MME