Clinical Trial Search

Primary: Proportion of Women Who Benefited of Performing Upfront Sentinel Lymph Node (SLN) Biopsy Ductal Carcinoma in Situ — 51 Participants

Primary: Success Rate in Removing Sentinel Lymph Nodes by Thoracoscopy — 31 participants

Primary: Quality of Life as Measured by the Breast Q — 61.9; 57.6; 74.2; 64.2 score on a scale

Primary: 5-year Disease-Free Survival — 84.4; 87.8 percentage of participants — p=0.004

Primary: Local Inbreast Breast Tumor Recurrence (IBTR) Rate — 4.3 Percentage of participants with IBTR

Primary: Collect Data to Refine and Verify the Tumor Detection Algorithm. — 11.3 Percentage

Primary: Change in Baseline of Cancer Cell Protein Levels of Human Epidermal Growth Factor Receptor (HER) Family Members (HER1-4) Following Neoadjuvant Endocrine Therapy. — 1…

Primary: Overall Response Rate as Measured by Clinical Exam, Standard Imaging, and Surgical Pathology Findings — 23; 0 Participants

Primary: Patients With Reduction in Incidental Radiation — 46 Participants

Primary: Feasibility of PBI Directed External Radiotherapy as Measured by Percentage of Participants Achieving a Dosimetrically Satisfactory Treatment Plan — 100; 100 percentage…

Primary: Percentage of Patients Who Are Free of Serious Treatment Related Toxicity — 50; 49 Participants

Primary: Number of Participants With Breast Cancer Recurrence, Including Recurrent DCIS and New Contralateral Tumours — 103; 120 Participants — p=0.33

Primary: Pathological Response for Basal Group 2 — 16; 14; 5; 11 Participants

Primary: Ipsilateral Recurrence Rate — 0 participants

Primary: (Phase A Only) Selection of Dose of LUM015 to be Used in Future Breast Trials — 2.1; 4.7; 4.2 Ratio

Primary: Patients With All Positive Margins Correctly Identified With the Device — 5 Patients w/ all positives identified

Primary: Percentages of Participants by EORTC Breast Cosmetic Rating Score at 24 Months Post-radiation Therapy — 17; 26; 24; 11 Participants

Primary: Number of Participants With a Pathological Complete Response — 21; 24; 99; 89 participants

Primary: Feasibility and Local Control of Early Breast Cancer Treated by Partial Breast Irradiation Using Different Radiation Doses Determined by Completion. — 98; 101; 124…

Primary: Proportion of Sentinel Lymph Nodes (SLNs) Flagged by the Two Methods — 0.86; 0.95 proportion of nodes

Primary: Number of Participants Experiencing Acute, Late Skin, and Subcutaneous Toxicity — 0 Participants

Primary: 18F-FES Uptake in DCIS — 1.43 SUV

Primary: The Mean Distance Between the Image-defined and Palpation-defined Edges of the Tumor. — 7.2 mm

Primary: Overall Survival — 82; 83 percentage of alive at 10 years — p=0.38

Primary: Percentage of Participants With Adequate Estrogen Suppression After 8 Weeks of Adjuvant Anastrozole 10 mg Daily — 76.0 percentage of participants

Primary: False Negative Rate (FNR) for Sentinel Lymph Node (SLN) Surgery After Chemotherapy When at Least 2 SLNs Were Excised in Women Initially Presenting With Biopsy-proven cN1…

Primary: The Residual Cancer Burden Grade III (RCB-III). — 23; 37; 14; 6 Participants

Primary: Local Recurrence — 3.1 percentage of participants

Primary: Complete Response Rate — 2; 8 Participants

Primary: Overall Survival (OS) — 34.6; 56.2 months — p=0.042