Phase 4 N=11 Wearing-Off Period of Pharmacological Dilation and Anisocoria
Anisocoria
Primary: Number of Participants With Constricting Response to Pilocarpine 1% in the Pharmacologically Dilated Eye — 3 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=26 Pupil Dilation for Treatment of IFIS
Intraoperative Floppy Iris Syndrome
Primary: Pupil Dilation Sized of the Treated Eye Compared to the Non-treated Eye — 6.76; 7.17 millimeters
N/A N=127 Interrater Reliability of Subjective Pupillary Assessments
Interrater Reliability Among Pupillary Assessments
Primary: 1. Explore the Interrater Reliability of Pupillary Assessments When Conducted in the Natural Setting by a Diverse Group of Practitioners — .54 Kappa score
N/A N=20 Investigation of Pupillometry as Guide for Extubation Readiness in Anesthetized Children
Anesthesia · Laryngospasm on Emergence
Primary: Extubation Success — 10; 10 Participants
Phase 4 N=28 Intraoperative Floppy Iris Syndrome
Cataract · Floppy Iris Syndrome
Primary: Corneal Endothelial Cell Loss — 9.85; -3.68 Percent change
N/A N=72 Clinical Evaluation of Morcher Artificial Iris Diaphragms
Aniridia · Iris; Deformity
Primary: Change in Light and Glare Sensitivity as Determined by a Clinical Glare Test (Primary Efficacy Measure) — 51; 12; 1 Participants
Phase 4 N=30 Safety and Efficacy of Fixed Combination Phenylephrine-Tropicamide for Pupil Dilation
Mydriasis
Primary: Mean Change in Pupil Diameter — 3.73; 6.46 millimeters
N/A N=44 Novel Portable Diagnostic Device for Automatic Detection of Relative Afferent Pupillary Defect
Multiple Sclerosis · Glaucoma
Primary: Number of Participants With Detected Relative Afferent Pupillary Defect (RAPD) — 44; 37 participants
Phase 3 N=64 Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation
Mydriasis
Primary: Change in Pupil Diameter From Baseline — 2.672; 2.583; 2.657; 2.569 millimeters