30 closest matches · ranked by relevance
Treatment Outcome
Primary: Change From Baseline in the Changes in Sexual Functioning Questionnaire Short-Form (CSFQ-14) Total Score at Week 8 — 8.8; 6.6 scores on a scale — p=0.013
Healthy
Primary: Semen Volume — 2.55 mL
Healthy
Primary: Change in 17-OH Pregnenolone — 120; 158; 171; 170 ng/dl — p=>0.8
Depression · Sexual Dysfunction
Primary: Change in Massachusetts General Hospital Sexual Dysfunction Inventory Scores — .249; .017 score on a scale — p=.016
Sexual Dysfunctions, Psychological · Hypoactive Sexual Desire Disorder · Erectile Dysfunctions
Primary: Number of Participants With a Score of ≤2 (Much/Very Much Improved) on the Clinical Global Impression Scale Adapted for Sexual Function (CGI-SF) at Week 6 Between…
Healthy Volunteers
Primary: Change From Baseline in the Changes in Sexual Functioning Questionnaire (CSFQ-14) Total Score Difference for Vortioxetine Versus Paroxetine at Week 5 in Full Analysis…
Major Depressive Disorder
Primary: Stockings of Cambridge (SOC) Mean Initial Thinking Time for 3-move Problems — -4485.50 milliseconds
Antidepressant Induced Sexual Dysfunction
Primary: Proportion of Participants in Remission Based on Arizona Sexual Experience Scale (ASEX) Score of 10 or Less After 12 Weeks of Treatment. — 2; 1 participants — p=0.55
Alopecia
Primary: Number of Participants With Adverse Events (AE) Related to Sexual Function in the Double-blind Treatment Period — 5; 9 Participants — p=0.27
Multiple Sclerosis
Primary: Sexual Dysfunction (as Measured by the Multiple Sclerosis Intimacy and Sexuality Questionnaire (MSISQ-19) ) — -0.697 units on a scale
Major Depressive Disorder (MDD)
Primary: Change in Total MADRS Scores From Baseline to Week 8 — -24.95; -18.95; -23.89 units on a scale
BPH · Depression · Suicide
Primary: Suicide (Based on Administrative Data Elements From Ontario Registrar General Death Database, National Ambulatory Care Reporting System, Hospital Discharge Abstracts…
Depression
Primary: Depressive Symptom Severity — 15.3; 14.1 units on a scale
Depression
Primary: Change From Baseline in Hamilton Depression Rating Scale at 8 Weeks — 11.81; 9.41 score on a scale
Infertility, Male · Depression
Primary: Number of Participants With Abnormal Sperm DNA Fragmentation at 6 Weeks — 0; 2 Participants
Sexual Dysfunctions, Psychological
Primary: Satisfying Sexual Event Monthly Change From Baseline at Final Visit — 0.8; 1.4; 1.6 number of events — p=0.0454
Major Depressive Disorder
Primary: Montgomery-Asberg Depression Rating Scale (MADRS) — 12.8 units on a scale
Depressive Disorder, Major · Anhedonia
Primary: Change From Baseline to Day 43 in the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score — -9.4; -10.0 Units on a scale — p==0.670
Major Depressive Disorder
Primary: Change From Baseline in HAM-D17 Total Score at Final On-therapy (FOT) Evaluation (Week 8 or ET) — -8.42; -9.28; -8.92 Units on a scale — p=0.175
Major Depressive Disorder
Primary: Total Discontinuation - Emergent Signs and Symptoms (DESS) Score Over the First 2 Weeks of the Double-blind Phase — 4.1; 4.8; 5.3 scores on a scale
Depression · Major Depressive Disorder · Unipolar Depression
Primary: Montgomery-Asberg Depression Rating Scale (MADRS) — 22.0; 18.0; 12.0; 14.0 units on a scale — p=.04
Depressive Disorder
Primary: Change From Baseline in the Hamilton Depression Scale (HAM-D 17 Items) Total Score — 19.8; 19.4; 14.7; 14.6 Score in scale — p=0.805
Depressive Disorder, Major · Anhedonia
Primary: Change From Baseline to Day 43 in the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score — -11.4; -12.3 Units on a scale — p==0.467
Sexual Dysfunctions, Psychological
Primary: Change From Baseline in the Number of Satisfying Sexual Events — 1.0; 0.6 sexual events
Erectile Dysfunction · Sexual Dysfunction
Primary: The Average Intravaginal Ejaculatory Latency Time (IELT) at Week 12 — 1.1; 3.4; 1.1; 5.2 minutes — p=<0.001
Depression
Primary: Hamilton Depression Rating Scale Remission Rates — 46.1; 17.6 Percentage of Remitters HDRS17
Contraception · Libido
Primary: Change From Baseline to Cycle 6 in the Total of Questions 1 to 6 of the Female Sexual Function Index (FSFI) - Full Analysis Set (FAS) — 6.45; 5.98 scores on a scale
Depressive Disorder, Major
Primary: 21-item Hamilton Depression Rating Scale Score (HAM-D) — 13.5; 15.6 units on a scale — p=0.71
Post-Schizophrenic Depression
Primary: Calgary Depression Scale for Schizophrenia (CDSS) — 8.31; 8.62 score on a scale
Schizophrenia
Primary: PANSS Negative Symptom Score — 21.5; 23 units on a scale — p=0.36