N/A N=114 Infant Aphakia Treatment Study (IATS)
Congenital Cataract
Primary: Visual Acuity — 0.80; 0.97 logMAR units — p=0.19
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=74 Safety and Effectiveness of the Calhoun Vision Light Adjustable Intraocular Lens (LAL)
Cataracts
Primary: Percentage of Eyes Achieving a Manifest Refraction Spherical Equivalent (MRSE) Within ± 0.50 D of the Intended Adjustment Target — 78.3; 80.0; 79.2 percentage of eyes
N/A N=210 Clinical Study to Evaluate the Safety and Effectiveness of the RxSight Light Adjustable Lens (LAL) in Subjects With Prior Corneal Refractive Surgery
Aphakia · Cataract
Primary: Magnitude of Manifest Cylinder (MRCYL) Compared Between the Two Study Groups, LAL and Control — -0.319; -0.452 Diopter
N/A N=66 Exploratory Study to Evaluate the Use of the RxSight Light Adjustable Lens (LAL) and the Light Delivery Device (LDD) to Improve Visual Outcomes
Aphakia · Cataract
Primary: Percent of Eyes With Uncorrected Distance Visual Acuity (UCDVA) of 20/20 or Better — 101 Eyes
N/A N=79 Single Center Exploratory Study To Evaluate The Use Of The RxSight Light Adjustable Lens (LAL) And The Light Delivery Device (LDD) To Improve Visual Outcomes
Aphakia · Cataract
Primary: Percent of Eyes With Uncorrected Distance Visual Acuity (UCDVA) of 20/20 or Better — 21 Eyes
N/A N=238 Clinical Trial of a Hydrophilic EMV Toric Lens RAO210T in the Correction of Aphakia and Corneal Astigmatism
Cataract · Corneal Astigmatism
Primary: Mean Magnitude of Residual Manifest Cylinder — -0.368; -0.780 Diopters
Phase 4 N=52 Contralateral ReSTOR / Monofocal or Phakic Eye
Cataracts
Primary: Visual Acuity — -0.04; -0.01; 0.14; 0.18 LogMar
Phase 3 N=122 One-Piece Hydrophobic Acrylic Intraocular Lens in Subjects Undergoing Cataract Extraction
Aphakia · Cataract
Primary: Visual Acuity — 108 Participants
N/A N=369 Prospective Clinical Trial to Evaluate the Safety and Effectiveness of the IOL
Cataract Unilateral · Aphakia
Primary: Best Corrected Distance Visual Acuity — 308 Participants
N/A N=30 AcrySof® Bilateral PanOptix(R) Spectacle Freedom and Patient Satisfaction Study
Cataract
Primary: Number of Participants Who Have Spectacle Independence — 27 Participants
Phase 2 N=61 Processed Amniotic Fluid (PAF) Drops After Photorefractive Keratectomy (PRK)
Photorefractive Keratectomy
Primary: Safety - Adverse Events Including Serious Adverse Events — 1; 1 Participants — p=1.000
Phase 4 N=34 Visual Function With Bilateral AcrySof® ReSTOR® Aspheric SN6AD1
Cataract
Primary: Binocular Visual Acuity at Distance, Near and Intermediate — 0.00; 0.13; 0.07; 0.00 LogMAR
N/A N=98 Corrected VA With Long-Term Follow-Up After AcrySof® Intraocular Lens (IOL) Implantation
Pseudophakia
Primary: Mean Change From Baseline in Best Corrected Visual Acuity (BCVA) at the Long-Term, Post-Implantation Visit — -0.06; -0.09; -0.07; 0.01 logMAR
Phase 4 N=76 Visual Function After Implantation of Bilateral AcrySoft ReSTOR Aspheric IOL
Cataract
Primary: Visual Acuity — 0.54; 0.06; 0.03; 0.04 logMAR
Phase 3 N=134 Polihexanide (PHMB) Eye Drops in Patients Affected by Acanthamoeba Keratitis
Acanthamoeba Keratitis
Primary: Clinical Resolution Rate — 84.8; 88.5 percentage of participants
N/A N=30 Evaluation of Quality of Vision and Spectacle Independence With the AcrySof® Panoptix® Intraocular Lens
Cataract
Primary: Number of Emmetropic Subjects Who Are Spectacle Independent — 21 Participants
N/A N=72 Clinical Evaluation of Morcher Artificial Iris Diaphragms
Aniridia · Iris; Deformity
Primary: Change in Light and Glare Sensitivity as Determined by a Clinical Glare Test (Primary Efficacy Measure) — 51; 12; 1 Participants
N/A N=35 Clinical Performance of a Phakic Intraocular Lens (IOL)
Presbyopia
Primary: Number of Eyes With Monocular Uncorrected Near Visual Acuity of 20/40 or Better at 40 cm 6 Months After Implantation — 66 Eyes
Phase 4 N=60 Visual Function After Bilateral Implantation of AcrySof® Toric
Visual Function
Primary: Uncorrected Visual Acuity (UCVA) — 0.06; 0.14 logMAR
N/A N=10 Early Feasibility Study to Evaluate the AccuraSee in Correcting Residual Refractive Errors After Cataract Surgery
Refractive Errors
Primary: Subjects With Stable Manifest Refraction Spherical Equivalent (MRSE) — 7 Subjects
Phase 4 N=120 Visual Function After Implantation of Bilateral AcrySof® Toric Natural Intraocular Lens
Cataract
Primary: Visual Acuity (VA) — 0.7; 0.06; 0.05; 0.05 logMAR
N/A N=55 Clinical Study to Evaluate the RxSight Light Adjustable Lens With the Light Delivery Device in Subjects With Preoperative Corneal Astigmatism
Cataract
Primary: Uncorrected Distance Visual Acuity (UCDVA) of 20/20 or Better — 45 Eyes
N/A N=24 A Comparison of Aspheric Toric Intraocular Lens (IOL) Implantation Versus Aspheric Non-Toric Lens Implantation
Cataract
Primary: Monocular Uncorrected Distance Visual Acuity (Monocular UCDVA) at Month 3 — 0.089; 0.225 logMAR
Phase 4 N=218 Visual Function After Implantation of Bilateral AcrySof ReSTOR Aspheric +3
Cataract
Primary: Uncorrected Visual Acuity (UCVA) — 0.05; -0.07; 0.15; 0.20 logMAR
N/A N=301 Patient Perception of Visual Quality and Function
Cataract
Primary: Use of Corrective Visual Aids (i.e., Spectacles, Contact Lenses) Post Intraocular Lens (IOL) Surgery — 71; 8; 9 participants
Phase 4 N=94 No Drop Post-Op Cataract Surgery
Cataract
Primary: Best Corrected Visual Acuity (BCVA) (Pre-op) — .28 LogMar
N/A N=9 Early Feasibility Study Using IOPCL MAG to Improve Near Vision in ARMD Subjects
Low Vision · Age Related Macular Degeneration
Primary: Tilt of the PCIOL and IOPCL MAG Complex — 9; 9 Eyes
Phase 4 N=75 Clinical Evaluation of a New Aspheric Intraocular Lens.
Cataract
Primary: Low Contrast Best Corrected Visual Acuity Following Cataract Surgery — 0.22; 0.24 LogMAR
Phase 2 N=68 Vision Restoration With a Collagen Crosslinked Boston Keratoprosthesis Unit
Keratolysis
Primary: Time From Surgery to Device Loss or Replacement — 95; 34 median weeks from surgery to removal
N/A N=20 Visual Outcomes of Vivity in Patients With High Axial Length
Cataract
Primary: Binocular Uncorrected Distance Visual Acuity (logMAR) — -0.1 logMAR