Phase 4 N=30 Emervel for the Correction of Lower Face Wrinkles & Folds
Nasolabial Folds · Marionette Lines · Wrinkles
Primary: Number of Subjects With Naturalness of Expression in Motion (2D Video) — 30 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=25 Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles
Rhytides · Wrinkle
Primary: Subject Satisfaction — 2.8 score on a scale
N/A N=66 Reliability of the Facial Wrinkle Scale in Japanese Subjects
Facial Rhytides
Primary: Inter-rater Reliability of Assessment of Facial Lines Using the 4-Point Facial Wrinkle Scale (FWS-A) — 0.653; 0.637; 0.647; 0.654 Kappa statistics
Phase 3 N=121 Clinical Trial to Assess Efficacy, Safety and Tolerability of Botulinum Toxin A (Xeomin®) in Treatment of Expression Wrinkles in the Upper Third of the Face
Skin Aging
Primary: Treatment Success — 89.08 % of participants
N/A N=40 Safety and Efficacy of Single Therapy Versus Double and Triple Therapy of the Pellevé™ Wrinkle Treatment System for the Treatment of Moderate Facial Wrinkles
Appearance of Facial Wrinkles
Primary: Fitzpatrick Wrinkle Assessment — 1.0; 1.5; 1.1 units on a scale, change in Fitzpatrick
N/A N=49 Prospective Pellevé™ Neck Wrinkle Study
Facial and Neck Rhytides
Primary: Change in Neck and Facial Wrinkles Using the Fitzpatrick Wrinkle Assessment — 74 percentage of participants
N/A N=15 Clinical Evaluation of Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles
Rhytides · Wrinkle
Primary: Change in Facial Wrinkles at 12 Weeks Post Final Treatment Compared to Baseline — -0.10 units on a scale
Phase 4 N=101 Prospective Evaluation of Facial Cosmetic Procedures
Cosmetic Techniques
Primary: Patient Satisfaction With Validated FACE-Q Aesthetics Survey — 28.0; 24.0; 36.0; 36.0 score on a scale
Phase 4 N=30 Effect of a Transcutaneous Electrical Nerve Stimulation (TENS) Device on Overall Facial Appearance
Ageing
Primary: Evaluate Overall Facial Improvement Assessed Live by the Investigator and Subjects Using the Global Aesthetic Improvement Scale (GAIS) at 12 Weeks Compared to Baseline…
N/A N=117 Investigation of the Effectiveness and Safety of MRZF111 in the Treatment of Décolleté Wrinkles
Décolleté Wrinkles
Primary: Responder Rate for Décolleté Wrinkles According to the Merz Aesthetics Scale (MAS)-At Rest Scale as Assessed by the Blinded Live Rater — 71.8; 83.7; 73.5 percentage of…
N/A N=24 Confirmatory Study: Assessing the Efficacy and Safety of the AcusMu Microneedle Patch in Treating Periorbital Wrinkles
Wrinkle
Primary: Proportion of Participants With Improvement in Periorbital Wrinkles From Baseline — 10; 2; 8; 2 Participants
Phase 4 N=20 Study of Restylane and Perlane in the Correction of Peri-Oral Wrinkles
Peri-oral Wrinkles
Primary: Local and Systemic Adverse Events — 100 percentage of participants
N/A N=72 Proof of Concept Anti-ageing Clinical Study in Healthy Subjects
Skin Aging
Primary: Change From Baseline in Ra (a dermaTOP Parameter), of Test Product Treated Versus (vs.) Untreated Side at Day 29 — -1.90; -0.12 Micro meter (µm) — p=0.0638
N/A N=20 Assess the Impact of Lip Rejuvenation on Projected First Impressions and Mood Perceptions
Lip Rejuvenation
Primary: First Impressions — 46.756; 27.769; 46.391; 34.404 score on a scale
Phase 3 N=26 Lateral Canthal Rhytides With Medium Depth Chemical Peel With or Without Pretreatment With Botulinum Toxin A
Wrinkles
Primary: Posttreament Results of Chemical Peel if Botox A is Added as Pre-treatment — 1; 2 Units on a wrinkle severity scale — p=.002
Phase 3 N=25 Assess Aesthetic Improvement With QM1114-DP in Subjects With Moderate to Severe Lateral Canthal Lines and Glabellar Lines
Glabellar Frown Lines · Canthal Lines
Primary: Responders Rate Using the Global Aesthetic Improvement Scale (GAIS) at Maximum Frown (Glabellar Lines) — 100 percentage of participants
Phase 2 N=20 Combination Facial Aesthetic Treatment in Millennials
Dermatological Non-Disease
Primary: FACE-Q Satisfaction With Facial Appearance Overall Scale — 42.35; 59.42 score on a scale
Phase 4 N=25 Changing in Skin Physiology After Microdroplet Placement of Stabilized Hyaluronic Acid in Aging Faces
Aging
Primary: Hydration Level — 53.19; 46.75 AU (arbitrary unit) — p=<0.05
Phase 2 N=50 Safety and Efficacy Study of Isolagen TherapyTM in Treatment of Facial Wrinkles and Creases
Facial Wrinkles and Creases
Primary: Change in Subject Assessment of Wrinkles Compared to Baseline on Subject Wrinkle Assessment — 2; 5; 15; 11 participants
Phase 4 N=34 Retinol on Human Skin Aging in East Asian Descent
Intrinsic Aging of Skin
Primary: Number of Genes Upregulated or Downregulated as Assessed by RNA Sequencing (Older Group, Retinol Versus Placebo) — 23; 21 genes
Phase 3 N=42 Cryo-Touch II for the Treatment of Wrinkles
Facial Wrinkles
Primary: Number of Participants With Effectiveness and Safety Success — 30; 41 participants
N/A N=51 Clinical Study Evaluating the Safety and Effectiveness of The Tixel Fractional System in The Treatment of Periorbital Wrinkles
Wrinkle · Periorbital · Tixel 2
Primary: Percentage of Participants With Safety Adverse Events — 3.92 Percentage of Participants
N/A N=99 A Study of Octave System for Improving Lines and Wrinkles of the Décolleté
Décolleté Wrinkles
Primary: Percentage of Treated Subjects With Improvement in Lines and Wrinkles of the Décolleté at Day 90 — 62.2 percentage of subjects
N/A N=124 Evaluation of the Efficacy and Tolerance of a Light Therapy Mask on Mild to Moderate Brown Spots and Moderate to Severe Facial Wrinkles
Skin Aging
Primary: Global Wrinkling - Change From Baseline to Week 12, Averaged Expert Grader Scores — 0.18; 0.30 Units on a scale — p=<0.001
Phase 4 N=64 Study to Evaluate Subject Satisfaction With Facial Appearance and Impact of Combined Facial Treatment
Facial Rhytides · Skin Folds · Loss of Volume and Skin Quality
Primary: Change From Baseline in the Rasch-transformed Score of the FACE-Q Satisfaction With Facial Appearance Scale. — 46.6 units on a scale — p=<0.0001
N/A N=149 Safety and Effectiveness of Sculptra Aesthetic for Correction of Cheek Wrinkles
Cheek Wrinkles
Primary: Responder Rate Based on the Blinded Evaluator's Live Assessment of the Galderma Cheek Wrinkles Scale (GCWS) at Rest at Month 12 — 26.1; 71.6 percentage of participants…
N/A N=51 TriActive+ Radiofrequency (RF) for Non-Invasive Treatment of Wrinkles and Rhytides
Wrinkles · Rhytides
Primary: Changes to the Surface by Visual and Photographic Analysis. — 41 participants
Phase 4 N=59 A Study to Evaluate Participant Satisfaction With Facial Appearance Overall and the Aesthetic and Psychosocial Impact of Combined Facial Treatment
Facial Rhytides, Skin Folds, Loss of Volume and Skin Quality
Primary: Change From Baseline in Rasch-transformed Score of FACE-Q Satisfaction With Facial Appearance Overall Scale to End of Study — 40.9; 37.8; 21.5; 32.9 score on a scale…
N/A N=120 Comparison of Redermic, Rejuva-A and Combination of Both Redermic and Rejuva-A in Subjects With Signs of Aging
Skin Aging
Primary: Skin Aging Measured With the Photonumeric Scale. — 21.25; 21.36; 21.21; 21.03 Units on a scale
Phase 3 N=40 Light Emitting Diode (LED) for the Treatment of Wrinkles
Skin Aging · Photoaging of Skin
Primary: Percent Change From Baseline in Microtopographic Profilometry Ra Values (Skin Roughness). — 3.62; 18.57 Percent change post-treatment — p=<0.0001