N/A N=87 Occurrence of Post-op Pain Following Gentlewave
Root Canal Infection · Endodontic Disease · Endodontic Inflammation
Primary: Level of Post-operative Pain (2018-2019) — 23.2; 11.56 score on VAS scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=118 Repeat Insult Patch Test APPENDIX I to HRL Standard Protocol #100
Allergic Sensitization
Primary: Number of Participants That Did Not Have Test Material Induced Clinically Significant Dermal Irritation — 110 Participants
N/A N=60 Dailies Total 1 Sphere Contact Lenses
Dry Eye · Contact Lens Complication
Primary: Visual Analog Scale (VAS) Contact Lenses Comfort Scores — 44 Score on a scale — p=<0.001
Phase 3 N=32 Spasmodic Dysphonia Pain
Spasmodic Dysphonia
Primary: Pain Experienced — 2; 2; 2 score on a scale
Phase 1 N=117 A Trial to Explore Symptomatic Therapy for Application Site Reaction to SPM962 in Healthy Subject
Healthy
Primary: Skin Irritation Score of the Application Site — 0.237; 0.289; 0.250 Scores on a scale
N/A N=100 Associated Joint Pain With Controlled Ankle Movement (CAM) Walker Boot Wear
Pain · Ankle Injuries
Primary: The Presence and Severity of Secondary Site Pain — 31 Participants
N/A N=92 Evaluation of Dryness in a Silicone Hydrogel Daily Disposable Contact Lens
Visual Acuity
Primary: Change From Baseline Comfort Score — 28.99; -0.29 Units on a scale
N/A N=100 Assessment of Novel Intraocular Injection Guide
Retinal Disease
Primary: Visual Analogue Scale (VAS) — 14; 33 mm on the VAS
N/A N=20 An Investigation of the Impact of Localized Topical Anesthesia of the Ocular Surface on End-of-day Contact Lens Discomfort
Visual Acuity
Primary: Subjective Comfort Scores — 79.25; 70.93; 61.00; 61.94 Units on a Scale
N/A N=64 Patient Comfort With Vascular Closure
Vascular Closure
Primary: Mean Score on the Visual Analogue Scale — 0.63; 0.59; 2.94; 5.03 Scores on a Scale
Phase 1 N=59 Cumulative Irritation Potential of 828 Ointment
Healthy Volunteers
Primary: Presence of Cumulative Irritation — 163.0; 109.0; 2073.0 units on a scale
N/A N=50 A Study to Evaluate the Cooling Sensation and Consumer Liking of a Skin Disinfectant Spray
Skin Care
Primary: Participant-perceived Cooling Sensation Immediately Post Product Application — 30.63; 30.15; 25.16 Score on a scale — p=0.0659
N/A N=80 Initial Performance of a Modified Daily Disposable Contact Lens
Refractive Error
Primary: Incidence (Number) of Ocular Discomfort Device-related Adverse Events (AEs) — 0; 0 Eyes
N/A N=222 Human Repeat Insult Patch Test to Evaluate Personal Lubricants
Erythema · Edema
Primary: Number of Patients That Showed Sensitization Reaction to the Test Material at Challenge — 0 Participants
Phase 2 N=6 The Qutenza Patch as Treatment for Disabling Treprostinil (Remodulin) Infusion Site Pain
Pulmonary Hypertension · Pulmonary Arterial Hypertension
Primary: Pain Score on a Visual Analogue Scale — 2.89 Visual Analogue Scale — p=0.03
N/A N=30 Neurolens and Contact Lens Discomfort
Contact Lens Discomfort
Primary: Change in Contact Lens Discomfort — -4.94; -8.67 Scores on a scale
Phase 4 N=30 Anesthetic Topical Adhesive (Synera™) to Reduce Injection Pain With Subcutaneous Multiple Sclerosis Medications
Multiple Sclerosis
Primary: Pain Rating — 5.7 units on a scale
Phase 4 N=46 Evaluation of Systane Complete for the Treatment of Contact Lens Discomfort
Contact Lens Discomfort · Dry Eye
Primary: Contact Lens Symptoms — 20.41; 18.92; 12.86; 17.92 Score on a Scale
Phase 4 N=40 Diclofenac Sodium Topical Gel to Reduce Injection Site Discomfort in Patients Taking Glatiramer Acetate
Multiple Sclerosis
Primary: Local Injection Site Reaction (0-6) Scale at Baseline, 2 Weeks — 3.39; 3.47 units on a scale — p=0.45
Phase 3 N=39 Irritation and Sensitization of Chlorhexidine Gluconate (CHG) Cloth
Surgery
Primary: Grading Scale for Visual Evaluation of Skin Condition — 0; 0; 0; 0 Scores Ranging (0-7)
N/A N=80 Initial Performance of a Daily Disposable Contact Lens Featuring Molded Marks
Refractive Error
Primary: Incidence of Ocular Discomfort Device-related Adverse Events (AE) — 0; 1 Events
N/A N=81 SPT for Sensitization of Collagen Dressing
Allergy Skin · Allergic Skin Reaction
Primary: Wheal Measurement — 0; 7.91; 0.32 mm
N/A N=20 Acute Comfort of Lubricant Eye Drop FID 111421
Dry Eye
Primary: Drop Comfort Upon Instillation — 1.7; 1.3 Units on a scale
N/A N=196 Non-dispense Comfort Comparison of Two Silicone Hydrogel Lenses
Myopia
Primary: Comfort After Insertion — 8.7; 7.7 Scale 1-10
N/A N=86 HRIPT for Collagen Dressing
Skin Sensitisation
Primary: Skin Sensitization Reaction Using Berger and Bowman Scale — 0; 0; 0; 0 score on a scale
Phase 2 N=54 Topical Anesthetic Use In Pessary Management
Pain
Primary: VAS Score at the Time of Pessary Removal Adjusting for Baseline Pain — 1.76; 3.81 Centimeters — p=.02
N/A N=47 Kinetic Anesthesia Device Study
Local Anaesthetic Complication · Pain
Primary: Pain of Lidocaine Injection, Measured by Visual Analog Scale. — 7.5; 26 mm on visual analog scale
N/A N=72 Nonpharmacologic Reduction of Periprocedural Distress and Drug Use
Dental Anxiety · Dental Pain · Drug Use
Primary: Number of Participants With Complete On-Site Data Sets — 37; 35 Participants
N/A N=120 The Effect of Lubricating Gel on Patient Comfort During Speculum Insertion.
Examination, Gynecological · Examination, Pelvic · Examination, Vaginal
Primary: Patient Discomfort During Speculum Insertion as Measured by a Visual Analog Scale. — 1.41; 2.15 score on a scale
N/A N=41 Test of Discomfort and Malaise of Two Different Urine Catheters in Healthy Volunteers
Spinal Cord Injury
Primary: Discomfort Measured on the Visual Analog Scale (VAS) — 3.7; 2.6 cm — p=0.0018