Clinical Trial Search

Primary: Adjusted Mean of Provocative Concentration of Methacholine Required to Produce a 20% Decrease in FEV1 (PC20FEV1) at 24 Hours — 0.793; 1.950; 2.504; 3.236 Log base 2…

Primary: Forced Expiratory Volume in 1 Second (FEV1) — 2.31; 2.25 liters

Primary: Change From Baseline in Asthma Control at 18 Months — 1.27; 1.17 score on a scale

Primary: Change From Baseline in Forced Expiratory Volume in 1 Second (FEV1) — 2.624; 2.626; 2.585; 2.579 L

Primary: Change From Baseline in FEV1 — 2.84 Liter

Primary: Change in Maximum Forced Expiratory Volume at One Second (FEV1) — 20; 20; 20; 19 percentage of change

Primary: FEV1 Percent Change Post-ipratropium — 10.8 percent change — p=0.032

Primary: Change Between Week 14 and Week 0 in the Morning (AM) Peak Expiratory Flow (PEF) — 24.4; 18.0; -1.4 Liters per minute

Primary: Percentage Change in the Ratio of Mean-normalized Perfusion Within Ventilation Defective Regions Relative to Outside — -17.8 percentage

Primary: Cellular Changes That Occur With Borage and Echium Seed Oil Supplementation — 5.06; 2.56 ng

Primary: The Percentage of Participants With Asthma Who Rated the Use of the ELLIPTA Inhaler as Easy or Very Easy, Among Those Who Demonstrated Correct Use of the Inhaler at the…

Primary: Late Asthmatic Response (LAR) - Smokers: Absolute Change From Saline in Minimum Forced Expiratory Volume in One Second (FEV1) Between 4-10 Hours (Hrs) After Allergen…

Primary: The Rate of Number of Subjects Whose PC20 is Less Than 8 mg/mL — 7 percentage of the subjects

Primary: 8-isoprostane Levels as Biochemical Markers for Nonenzymatic Oxidative Stress in Asthma — 292.4; 421.8 pg/ml

Primary: Change From Baseline in Normalized Forced Expiratory Volume in 1 Second (FEV1) Area Under the Curve From 0 to 15 Minutes (AUC0-15 Min) Post-dose — 2.969; 2.970; 2.955…

Primary: Maximum Percent Fall in Forced Expiratory Volume in 1 Second (FEV1) After Exercise Challenge at 2 Hours Post-dose in Patients With Exercise-Induced Bronchoconstriction…

Primary: Adenosine Challenge Test — 18.46; 142.61 mg/ml

Primary: Percentage of Participants From Each Stratum Who Demonstrated Correct Use of the ELLIPTA DPI at Visit 2, Attempt 1 (Day 28) — 92; 93 Percentage of participants

Primary: Mean Rate of Wheezing Attacks — 3.57; 5.72 wheezing attacks/per patient — p=0.05

Primary: Asthma Control Test — 19.3; 19.8; 19.1; 19.6 units on a scale — p=0.8

Primary: Number of Asthma Episodes Culminating in Asthma Attack Over the 1-year Treatment Period — 0.99; 1.06; 1.05 Asthma attacks within episodes per year — p=0.510

Primary: The Primary Outcome is the Change in Bronchodilation and Bronchoprotection After Broccoli Sprout Extract — 10.3; 26.7 index

Primary: Maximum Percent Fall in FEV1 After Exercise Challenge at 2 Hours Post-dose Compared With Pre-exercise Baseline in Patients With Exercise-induced Bronchospasm (EIB)…

Primary: Exhaled Nitric Oxide — 67.0; 54.8 parts per billion (ppb) — p=<0.03

Primary: Post-dose PC20 Concentration After Receiving Differing Doses of Test, Reference, or Placebo — 0.608; 3.779; 4.432; 3.928 log(mg/mL) — p=<0.0001

Primary: Central and Peripheral Elastance — 391; 461; 587; 334 cmH2O/L

Primary: Maximum Percent Fall in FEV1 After Exercise Challenge at 2 Hours Postdose Compared With Pre-exercise Baseline in Patients With Exercise-induced Bronchospasm (EIB)…

Primary: Time to First Severe Exacerbation — 43.75; 49.43 Days — p=0.758

Primary: Subjects Experiencing Severe Exacerbations (Rates) — 132; 118; 118; 106 Participants

Primary: Airway Wall Thickness — 1.5; 1.5; 1.4; 1.6 mm — p=0.2