30 closest matches · ranked by relevance
Coronary Artery Disease · Carotid Artery Diseases · Atherosclerosis
Primary: Annualized LRNC Volume Change in Carotid Plaque Composition, as Assessed by MRI — -4.6; -15.1; -9.4 mm^3/year
Primary PCI for STEMI
Primary: Rate of Complete ST-segment Elevation Resolution at 60 Minutes After the End of the Procedure — 38; 58 Participants
Aortic Stenosis · Inflammation · Thrombosis
Primary: Platelet Reactivity — 275.5; 251; 234; 128.5 Platelet Reactivity Units
Atherosclerosis
Primary: Change in Necrotic Core Volume — 0.07 mm^2
Cardiovascular Disease · Peripheral Artery Disease · Critical Limb Ischemia
Primary: Number of Patients in Which Platelet Activity Measurements Were Associated With Short-term Cardiovascular Events — 31; 16 participants
Atherosclerosis · Ischemia · Myocardial Infarction
Primary: Kaplan-Meier Estimate of the Percentage of Participants Who Experienced Cardiovascular (CV) Death, Myocardial Infarction (MI), Stroke, or Urgent Coronary…
Myocardial Infarction
Primary: Concentration of Platelet Extracellular Vesicles/ml — 2690000; 4310000 Platelet Extracellular Vesicles/mL
Myocardial Infarction
Primary: 6-month Reocclusion — 1; 4 participants
Ischemic Stroke
Primary: Symptomatic Intracerebral Hemorrhage (ICH) — 1; 1 participants
Metabolic Syndrome
Primary: Ex Vivo Effects of Treatment With Vytorin Versus Zocor for 6 Weeks on Platelet Alpha Thrombin PAR-1 Receptor Expression — 35.4; 34.5; 23.6; 22.5 ng/dl
Critical Limb Ischemia
Primary: To Determine Platelet Inhibition Before and After Switching for Two Weeks From Clopidogrel to Ticagrelor in Patients With CLI. — 173; 140; 71; 63 P2Y12 reaction units…
Myocardial Infarction
Primary: Maximal Platelet Aggregation — 52; 64; 74 percent aggregation — p=0.011
Cardiovascular Diseases · Heart Diseases · Myocardial Infarction
Primary: Number of Patients That Had a First Occurrence of the Primary End Point (Composite of Death From Any Cause, Nonfatal MI, or Class IV HF) — 230; 219 participants
Cardiovascular Diseases · Atherosclerosis · Myocardial Infarction
Primary: Change in Nitric Oxide Formation From Baseline to 3 Months. — 10.0; 11.2; 10.0; 11.0 ng/mL
Myocardial Infarction · Diabetes Mellitus · Peripheral Arterial Disease
Primary: Maximal Platelet Aggregation in DM — 65; 78 percentage of aggregation — p=>0.05
CVD
Primary: Number of Participants With Occlusion and Restenosis at One Year — 58; 56 participants
Peripheral Arterial Disease · Peripheral Vascular Disease
Primary: Primary Efficacy Endpoint - Mean Reduction in Percent Stenosis — 39 Participants
Left Atrial Appendage Closure · WATCHMAN Device Implantation
Primary: Comparison of Thrombin Induced Platelet-fibrin Clot Strength (TIP-FCS) Between Patients With and Without Device Related Thrombosis (DRT) Assessed at 1-year of Watchman…
Prevention of Subclinical Atherosclerosis Progression · Prevention of Cognitive Decline
Primary: Progression of Subclinical Atherosclerosis — 0.013; 0.011 mm per year — p=0.31
Atrial Fibrillation · Thrombi
Primary: Number of Patients With Atrial Thrombus and a Zero ATE Score — 2; 816; 27; 2227 Participants
Coronary Artery Disease
Primary: TRAP-induced Platelet Aggregation — 74; 77 percentage of aggregation — p=<0.05
Myocardial Infarction
Primary: Cardiovascular Event - Myocardial Infarction, Stroke, Death — 17; 6 Participants — p=0.007
Metabolic Syndrome X · Overweight · Hypertension
Primary: Change in Carotid Intima-media Thickness From Baseline to Year 1 — 0.766; 0.765; 0.758; 0.768 millmeter — p=0.7279
Cardiovascular Diseases · Vascular Dilation
Primary: Change in Reactive Hyperemia Index (RHI) — -0.01; 0.21 percentage index change
Acute Coronary Syndrome
Primary: Thrombolysis in Myocardial Infarction (TIMI) Clinically Significant Bleeding Events (Primary Safety) — 36; 17; 109; 43 Patients
Acute Ischaemic Stroke · Transient Ischaemic Attack
Primary: Composite of Subsequent Stroke or Death — 303; 362 Participants — p=0.015
Acute Coronary Syndrome
Primary: Platelet-thrombus Formation in an ex Vivo Model of Thrombosis — 56.3; 35.2 percent change
Coronary Artery Disease · Healthy Participants
Primary: Percent Change From Baseline in Thrombus Area — 10.0; 538.6; 104.2; -14.9 Percent Change
Cardiovascular Diseases · Metabolic Syndrome X · Atherosclerosis
Primary: Change in Nitric Oxide Formation From Baseline to 3 Months — 27.6; 27.0; 31.4; 25.7 ng/mL
Aortic Valve Stenosis · Cardiovascular Diseases · Heart Valve Diseases
Primary: Rate of Patients With at Least One Prosthetic Leaflet With >50% Motion Reduction as Assessed by Cardiac 4DCT-scan — 11; 2 Participants — p=0.01