N/A N=88 A Prospective, Contralateral, Eye to Eye Comparison of SMILE Surgery to LASIK Surgery
Myopia
Primary: Percentage of Participant Eyes With an Uncorrected Visual Acuity of 20/20 or Better — 94; 83 percentage of participant eyes
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=14 A Comparison of LASIK Outcomes Using Two Femtosecond Lasers
Myopia · Astigmatism
Primary: ETDRS Uncorrected Visual Acuity — 5; 5 Eyes
Phase 4 N=52 Contralateral ReSTOR / Monofocal or Phakic Eye
Cataracts
Primary: Visual Acuity — -0.04; -0.01; 0.14; 0.18 LogMar
Phase 4 N=40 Contralateral Comparison of Three Excimer Laser Systems in Performing LASIK
Myopia · Astigmatism
Primary: 1 Day Postoperative Lasik Uncorrected Visual Acuity — -0.04; -0.05; 0.06 LogMar
Phase 4 N=76 Visual Function After Implantation of Bilateral AcrySoft ReSTOR Aspheric IOL
Cataract
Primary: Visual Acuity — 0.54; 0.06; 0.03; 0.04 logMAR
N/A N=33 LASIK Flap Thickness and Visual Outcomes Using the WaveLight FS200 Femtosecond Laser
Myopia
Primary: Evaluation of LASIK Flap Thickness — 105.8; 112.9 micrometers — p=.003
N/A N=300 Patient Reported Outcomes With WaveLight LASIK
Myopia
Primary: Patient Satisfaction — 285 Participants
N/A N=25 A Comparison of Visual Function After Bilateral Implantation of Presbyopia-Correcting Intraocular Lenses (IOLs)
Cataract
Primary: Mean Binocular Defocus VA at Month 3 — 0.78; 0.59; 0.65; 0.45 logMAR
Phase 4 N=80 GenTeal in Perioperative Treatment of Laser Assisted in Situ Keratomileusis LASIK Patients
Corneal Epithelium Defect
Primary: Epithelial Healing After Laser Assisted in Situ Keratomileusis (LASIK) Surgery — 4.3; 3.5; 9.2; 9.0 Clock Hours
Phase 2 N=137 Safety and Efficacy Study of Cyclosporine Ophthalmic Emulsion in Post-LASIK Patients
Dry Eye Syndromes
Primary: Percentage of Patients With Clinical Success at Month 6 — 64.3; 58.1 Percentage of Patients
Phase 3 N=170 Safety and Effectiveness of Wavefront-Guided LASIK Corrections of Myopic Refractive Errors
Myopia
Primary: Percentage of Eyes With Loss of More Than 2 Lines Best Spectacle Corrected Visual Acuity (BSCVA) — 0 percentage of eyes
N/A N=97 WaveLight® Refractive Myopic Study
Refractive Error
Primary: Least Squares Mean Difference in Binocular UCVA at 1 Month Post-Treatment and Pre-Treatment Binocular BCVA — -0.0519 logMAR
Phase 1 N=357 Use of the VisuMax™ Femtosecond Laser
Myopia
Primary: Effectiveness- Predictability of Participant Refractive Outcomes — 291; 306 Participants
N/A N=30 Accuracy of LASIK Flaps Created With the LenSx® Femtosecond Laser - A Pilot Study
Myopia · Hyperopia
Primary: Flap Thickness Accuracy Within the Central Zone at Month 3 Postoperative — 125.8 micrometers
N/A N=70 Clinical and Refractive Outcomes After Contoura® Refractive Surgery Planned Using Phorcides Surgery Planning Software
Refractive Errors
Primary: Residual Refractive Cylinder — 0.04 diopters
Phase 2 N=621 Study of Cyclosporine in Post-LASIK Patients
Laser In Situ Keratomileusis
Primary: Time to Cure — 189.0; 194.0; 189.0 Days
N/A N=114 VisuMax Femtosecond Laser Small Incision Lenticule Extraction for the Correction of High Myopia
Myopia · Refractive Errors
Primary: Variability of the Refractive Predicatibility — -0.22 Diopters
N/A N=84 Conventional Surgery vs. Verion/VerifEye
Cataract · Astigmatism
Primary: Residual Refractive Cylinder — 0.28; 0.33 Diopters
Phase 3 N=212 Safety and Efficacy Study of Topography-Guided LASIK to Treat Myopia and Hyperopia
Myopia · Hyperopia
Primary: Percentage of Eyes With Manifest Refraction Spherical Equivalent (MRSE) +/- 0.50 D — 94.78 Percentage of Eyes
N/A N=15 Glaucoma Surgery Using the ViaLase Laser System
Glaucoma · Glaucoma, Open-Angle
Primary: Mean IOP — 12.7 mmHg
N/A N=72 Technolas 217z Laser With Zyoptix Aspheric Algorithm Used for the LASIK Treatment of Myopia and Myopic Astigmatism.
Myopia · Astigmatism
Primary: Percentage of Eyes With Uncorrected High Contrast Distance Visual Acuity of 20/40 or Better — 99.2 percentage of eyes
N/A N=40 Clinical Outcomes With Bilateral Implantation of Odyssey IOLs
Cataract
Primary: Visual Acuity at Distance (6m) logMAR — 0.00; -0.02; 0.02; 0.00 logMAR
N/A N=230 70 vs 110 Degree Side-cut Angles in Femtosecond LASIK
Operative Incision
Primary: Uncorrected Visual Acuity at One Year — -0.082; -0.094 logMAR Visual Acuity
N/A N=167 Prospective S&E Study of Wavefront-guided PRK for Myopia With iDesign Advanced Wavescan Studio™ System and Star S4 IR™
Stable Myopic Refractive Error, With or Without Astigmatism
Primary: The Percentage of Eyes Achieving the Target of Monocular Uncorrected Visual Acuity of 20/40 or Better — 324 Eyes
N/A N=84 Safety and Effectiveness of Wavefront-guided LASIK for the Correction of Mixed Astigmatism
Astigmatism
Primary: Line Loss of More Than Two Lines for Best Spectacle Corrected Visual Acuity (BSCVA) — 149 eyes
N/A N=30 Clinical Investigation of the WaveLight® EX500 Excimer Laser
Hyperopia · Hyperopic Astigmatism
Primary: Percentage of Eyes With Manifest Refraction Spherical Equivalent (MRSE) Within ±0.50 Diopter (D) at Refractive Stability — 98.3 percentage of eyes — p=<0.0001
N/A N=94 Simultaneous TransPRK and Corneal Collagen Cross-Linking
Keratoconus
Primary: Change in LogMAR Corrected Distance Visual Acuity (CDVA) — -0.13; -0.05 LogMAR CDVA — p=0.03
Phase 4 N=42 Visual Outcomes of Subjects Bilaterally Implanted With ReSTOR Aspheric +4 vs. Tecnis or Acri.LISA
Cataract
Primary: Uncorrected Visual Acuity (UCVA) at Distance, Near and Intermediate — 0.02; 0.01; 0.20; 0.20 logMAR
N/A N=52 Synergy Lens Outcomes Evaluation
Presbyopia · Pseudophakia
Primary: Binocular Distance Corrected Near Visual Acuity at 40 cm Under Photopic Conditions — 0.01 logMAR
N/A N=58 The Accuracy of Flap Thickness Versus the Pre-determined Surgical Planning Using WaveLight® FS200
Myopia
Primary: The Resultant Thickness of the FS200 Created LASIK Flap Compared to Plan at the Surgical Visit. — 0.64 um