Clinical Trial Search

Primary: Brain Activity (Beta Power) in Left vLPFC — -88.78; 1437.64; 13.43; -128.00 Percentage of change post versus pre — p=0.29389090

Primary: Change From Baseline In Young-Mania Rating Scale (YMRS) Score At Week 3 — -10.6; -10.8 units on a scale — p==0.8797

Primary: Symptoms of Mania, as Measured by Young Mania Rating Scale — 5.7; 11.1; 10.0 units on a scale

Primary: Change in the Young Mania Rating Scale (YMRS) Total Score From Baseline to Final Assessment (Day 28) — -25.7; -26.1 score on a scale

Primary: Change From Baseline In Young-Mania Rating Scale (YMRS) Score At Week 3 — -12.3; -10.7 units on a scale — p==0.1011

Primary: Change From Baseline to 3 Week Endpoint in Young Mania Rating Scale (YMRS) Total Score — -12.6; -14.3; -6.8 units on a scale — p=<0.001

Primary: Young Mania Rating Scale (YMRS) — -11.3; -5.3 scores on a scale — p=<0.001

Primary: Young Mania Rating Scale (YMRS) — 5.5; 11.8; 7.5; 3 score on a scale

Primary: Change in the Young Mania Rating Scale (YMRS) Total Score From Baseline to Final Assessment (Day 43) — -22.8; -20.1 Scores on a scale

Primary: The Montgomery-Asberg Depression Rating Scale (MADRS) — 31.95; 9.95; 10.95 score on a scale — p=<.001

Primary: Sedation Score — 0.5; 0.5; 0.6; 0.6 units on a scale

Primary: Montgomery Asberg Depression Rating Scale (MADRS) (Montogomery and Asberg, 1979) — 26.20; 20.20; 16.11; 15.22 units on a scale — p=0.05

Primary: Change From Baseline to Week 4 in Young Mania Rating Scale (YMRS) Total Score — -14.0; -10.0 Change from Baseline in YMRS Total Score

Primary: Number of Participants With Clinical Response [ Time Frame: At 6 Weeks Following Course of tDCS Treatment ] — 34 Participants

Primary: Proportion of Participants Not Experiencing Relapse to Any Mood Episode Through Week 52, Phase 3 — 1.00; 1.00; 0.95; 0.96 proportion of participants — p=0.014

Primary: Change From Baseline in the Young Mania Rating Scale (YMRS) Total Score at Week 3 — -15.3; -19.6 score on a scale — p=0.0004

Primary: Change From Baseline in the Young Mania Rating Scale (YMRS) Total Score at Week 3 — -12.5; -18.6; -18.5 score on a scale — p=<0.001

Primary: Change of Mania Symptoms Assessed by Young Mania Rating Scale (YMRS) — -14.9 Units on a scale

Primary: Mean Change in Young Mania Rating Scale (YMRS) Scores From Baseline to Endpoint. — -10.15; -7.68 units on a scale — p=<0.001

Primary: Change in Vigilance Assessed by the Melbourne Decision Making Questionnaire (MDMQ) — .176 units on a scale

Primary: Young Mania Rating Scale (YMRS) — -18.8 scores on a scale

Primary: Change From Baseline in Total Score on the Young Mania Rating Scale (YMRS) (LOCF Data Set) — -11.54; -13.57 Units on a scale — p=0.058

Primary: Remission — 16; 13 Participants — p=<0.0001

Primary: Change From Baseline in the Young Mania Rating Scale (YMRS) Total Score at Week 3 — -8.91; -15.02 score on a scale — p=<0.0001

Primary: Cocaine Use Determined by Urine Analysis — 62.50; 50.00 percentage of participants no cocaine — p=.4637

Primary: Change in Hamilton Depression Rating Scale (HDRS-21) Total Score From Baseline at Week 6. — -2.7647; -4; -3.4259; -6.5875 score on scale — p=0.29

Primary: 17-item Hamilton Depression Rating Scale (HDRS) — 20; 6; 6; 2 units on a scale

Primary: Change From Baseline to Endpoint in Young Mania Rating Scale (YMRS) Total Scores - Olanzapine Monotherapy Arm Only — -3.0 units on a scale

Primary: Measure of Response by Change From Baseline to End of Study in BISS Depression and Mania Scale Scores — 35.7; 61.8; 25; 48 percentage change in score on BISS scale…

Primary: Post-Lithium Treatment Hamilton Depression Rating Scale (HDRS) — -44.49 Percent Change in HDRS-24 Score