N/A N=30 Wrist Fracture Evaluation With a Desktop Orthopedic Tomosynthesis System
Fracture
Primary: Sensitivity — 96.7 percent of scans with a fracture
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=60 Fixation of Unstable Distal Radius Fractures
Distal Radius Fractures
Primary: Average Difference Between Michigan Hand Outcomes Questionnaire Scores — 85.2; 91.8 units on a scale
Phase 3 N=16 Prospective Biomarkers of Bone Metabolism in Hemophilia A
Hemophilia · Bone Disease
Primary: Bone Biomarker Density (BMD) — -0.74; -0.16; -0.16 Z-Score
Phase 4 N=13 Fracture (FX) Improvement With Teriparatide: FiX-IT Study
Osteoporosis · Atypical Femoral Fracture
Primary: Radiologic Evidence of Bone Healing — 12.6; 11.2; 15.4; 13.2 units on a scale
N/A N=141 Build Better Bones With Exercise
Osteoporotic Fractures · Spinal Fractures
Primary: Feasibility of Recruitment and Retention — 66; 64 Participants
N/A N=20 Reduction and Fixation of Metatarsal Neck Fracture by Metaizeau's Technique
Displaced Metatarsal Neck Fracture
Primary: Time of Union — 5.8 weeks
Phase 2 N=22 Phase 1/2a Study on Allogeneic Osteoblastic Cells Implantation in Delayed-Union Fractures
Long Bone Delayed-Union Fracture
Primary: Percentage of Responders at 6 Months (Efficacy of ALLOB) — 100 percent of patients
N/A N=216 Randomized Trial of Casting Techniques for Displaced Forearm Fractures
Displaced Forearm Fractures
Primary: Loss of Radius Fracture Reduction — 35; 35; 66; 66 participants — p=1.00
N/A N=66 Skeletal Versus Cutaneous Traction For Treatment of Femur Fractures
Femur Fracture
Primary: Difference in the Two Groups in Regards to Resident Time. — 24; 57 minutes
N/A N=53 Immediate Weight Bearing Versus Protected Weight Bearing in Supracondylar Distal Femur Fractures
Closed Supracondylar Fracture of Femur
Primary: Time to Distal Femur Fracture Healing by Radiographic Evidence — 1.75; 2.15 months
N/A N=33 Use of a Reinforced Injectable Calcium Phosphate Bone Cement in the Treatment of Tibial Plateau Fractures
Tibial Fractures
Primary: Duration of Time the Patient Was in the OR as a Measure of Effectiveness of the Treatment — 107.0 Minutes
Phase 3 N=122 Effect of Teriparatide on Hip Fracture Healing
Femur Neck Fracture
Primary: Percentage of Participants With No Revision Surgery at 12 Months After Internal Fixation of a Low-Trauma Femoral Neck Fracture — 87; 86 percentage of participants
N/A N=81 Safety and Efficacy Study of Treatment of Pathological Fractures in Humerus
Humerus Fracture Metastatic Bone Disease
Primary: Change in Pain — -52.7 units on a scale — p=0.615
Phase 2 N=402 Study of Romosozumab (AMG 785) in Tibial Diaphyseal Fractures Status Post Intramedullary Nailing
Fracture Healing
Primary: Time to Radiographic Healing — 16.4; 18.6; 18.3; 18.2 weeks — p=0.3598
N/A N=20 Orthopaedic Treatment Proximal Humeral Fractures
Proximal Humeral Fracture
Primary: Constant Scale Evaluation at 3 Months and 12 Months From the Date of Trauma — 40.1; 51.8 units on a scale — p=<0.01
Phase 2 N=35 PTH(1-34) and Pelvic Fracture Healing - a Randomized Controlled Trial
Osteoporotic Fractures
Primary: Number of Participants With Evidence of Cortical Bridging for Fracture Healing — 9; 8 Participants
N/A N=156 A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Distal Femur Fractures
Femoral Fractures
Primary: EQ-5D — 69.23; 72.81; 74.24; 73.04 units on a scale
N/A N=36 chronOS Inject in Proximal Tibial Fractures
Closed Proximal Tibial Fracture Schatzker I - VI · Closed Proximal Tibial Fracture AO-OTA 41 · Closed Proximal Tibial Fracture AO-OTA 42
Primary: Fracture Union — 27; 2 participants
N/A N=12 Effect of High Doses of Radiation on Bone Structure and Metabolism
Malignant Bone Tumors
Primary: Change in Bone Mineral Density (Tb. BMD) — 4.5; -39.3; -8.7; -54.7 mg/cm^3
N/A N=99 A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Proximal Tibial Fractures
Tibial Fractures
Primary: Participants' Quality of Life at 3 Months — 0.60; 0.59 score on a scale
N/A N=142 BBOT: Bacterial Burden in Ortho Trauma Procedures
Orthopaedic Trauma Infections
Primary: Number of Participants With Tissue Samples Identified With Bacterial DNA According to Highly Sensitive Bacterial Assays — 10; 24; 20 Participants
N/A N=9 Computed Tomography for Evaluating Supination-external Rotation Type Ankle Fractures
Supination-external Rotation Ankle Fractures
Primary: Medial Clear Space Distance in the Ankle Joint — 1.41 mm
N/A N=90 Exploration of Blood Flow Regulation to Bone in Humans
Bone Blood Flow Regulation
Primary: Tibial Blood Perfusion — 0.54; -1.47; 0.43; 2.08 μM (concentration)
Phase 4 N=277 Study Evaluating InductOs in Diaphyseal Tibia Fractures
Tibial Fractures
Primary: Number of Patients With Healed Fractures — 83; 66; 8; 13 patients — p=0.0541
Phase 3 N=39 Second Study of the Effect of Teriparatide on Hip Fracture Healing
Femur Neck Fracture
Primary: Percentage of Participants With No Revision Surgery at 12 Months After Internal Fixation of a Low-Trauma Femoral Neck Fracture — 74; 93 Percentage of participants
N/A N=1,108 Using Alternative Implants for the Surgical Treatment of Hip Fractures (The FAITH Study)
Femoral Neck Fractures
Primary: Revision Surgery — 107; 117 Participants
N/A N=20 ICG Fluorescence Imaging in Trauma Patients
Trauma Injury
Primary: Percent of Patients That Complete the Protocol — 61.5; 83.3; 0 percentage of completed patients
Phase 2 N=10 Healthy Body, Healthy Bones After Bariatric Surgery Trial
Bariatric Surgery Candidate · Bone Loss · Bone Resorption
Primary: Change in Hip Bone Mineral Density (BMD) — 0; -.03 g/cm2
N/A N=95 Pelvis RCT: Impact of Surgery on Pain in Lateral Compression Type Pelvic Fractures
LC Pelvic Fracture
Primary: Posttreatment Pain — 5.3; 6.2; 4.2; 5.6 scores on a scale
N/A N=225 Incidence and Risk Factors for Surgical Site Infection After Intramedullary Nailing of Femoral and Tibial Fractures
Fracture Fixation, Intramedullary · Surgical Wound Infection
Primary: Incidence of Surgical Site Infection (SSI) Relating to Intramedullary Nailing for Fixation of Diaphyseal Femoral and Tibial Fractures — 26; 195 Participants