Clinical Trial Search

Primary: • Number of Patients Receiving at Least a 1-grade Improvement in the Physicians Global Improvement Assessment (PGIA) of Two Target Nails. — 10; 11 patients

Primary: Physician Global Improvement Assessment (PGIA) — 5; 2; 7; 1 Fingernails

Primary: Change From Baseline in the Physician's Global Assessment (PGA) of Target Fingernails #1 and #2 — -1.4; -1.4 scores on a scale

Primary: Observe Stability of Nail Polish as Evidenced by Serial Photography With Efinaconazole Application in Terms of Days — 1.5; 5; 15; 5 days of stability

Primary: Modified NAPSI Score (Nail Psoriasis Severity Index) — 6.3; 6.0 units on a scale

Primary: Mean Percent Change of mNAPSI (Modified Nail Area Psoriasis Severity Index) at Week 36 Compared to Baseline for All Nails. — 64.1 percentage of reduction in mNAPSI score…

Primary: Number of Participants Enrolled Within One Year — 12; 11 Participants

Primary: Change From Baseline in Nail Length of Hands — 13.49; 15.10; 1.34; 1.51 mm — p=0.532

Primary: Change From Baseline in Radial Trabecular Volumetric Bone Mineral Density (Tr vBMD) at Month 12 — 1.004; 0.993; 0.992 ratio — p=0.644

Primary: The Proportion of Subjects Who Achieve at Least a 75% Improvement From Baseline in Total mNAPSI at Week 28. — 0.042; 0.255 proportion of subjects — p=0.00311

Primary: NFC Blood Flow at Baseline and 15 Minutes — 72.52; 83.94; 93.01; 60.50 pL/s

Primary: Bone Density (Low Areal Bone Mineral Density (aBMD)) — -1.3; -0.9; -2.4; -1.2 z-score

Primary: Mycological Cure — 12 Participants