N/A N=18 Fractional Ablative Laser Treatment for Skin Grafts
Burn Scar · Skin Graft Scar
Primary: Contracture of Scar Surface Area (Percentage of Original Area) — 97; 97 percentage
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=29 Fractionated Carbon Dioxide Laser and Burn Scar Contractures: Evaluation of Post-Treatment Scar Function and Appearance
Burn Scars
Primary: Scar Pigmentation, Baseline vs 15-months — 50.93; 49.59 units on a scale
N/A N=54 Effectiveness of Pressure Garment Therapy After Burns
Hypertrophic Scarring After Burn Injury
Primary: Pressure Under Compression Garment — 25; 6.4 mm Hg
N/A N=30 Post Excision/Mohs Scar Laser Resurfacing
Skin Cancer
Primary: MMSS for Scar Halves Treated — 8.4; 8.7 score on a scale
N/A N=10 An Open Single-centre Investigation Evaluating Efficacy in Second Degree Partial Thickness Burns Using a Silicone Contact Layer Containing Silver.
Wound Healing
Primary: Number of Participants With Wound Healing — 10 participants
N/A N=6 Laser Resurfacing Versus Dermabrasion for Scar Revision
Cicatrix · Dermabrasion · Coagulation, Laser
Primary: Safey Data Score Based on Ordinal Ratings of Erythema, Edema, Bleeding, Eschar After Resurfacing — 1.33; 3.00; 0; 0 units on a scale
N/A N=65 Exercise in Burn Survivors: Cooling Modalities
Burn Injury
Primary: Change in Core Temperature (°C) During Control Intervention — .578; .920; .622; .885 °C
Phase 2 N=60 Light Emitting Diode-Red Light (LED-RL) Phototherapy for Skin Scarring Prevention
Fibrosis · Skin Scarring · Skin Wound
Primary: Change in Scar Pliability Between the Treated and Control Incision Sites as Measured by Skin Elasticity at 6 Months Compared to Baseline
N/A N=51 Treatment of Surgical Scars Following Breast Augmentation, Abdominoplasty or Face Lift
Surgical Scar · Breast Augmentation · Abdominoplasty
Primary: Improvement of Surgical Scars at 12 Months Compared to Baseline (Pre-treatment) as Evaluated by 3 Independent Blinded Reviewers Using the General Aesthetic Improvement…
Phase 4 N=20 Comparison of Wound Bed Establishment in Facial Burns
Burns
Primary: Time to Wound Epithelialization — 37.4; 37.6 days — p=.0853
N/A N=45 A Clinical Investigation to Evaluate Efficacy of Mepitel Ag in Partial Thickness Second Degree Burns
Burns · Wound Healing
Primary: Number of Subjects Healed at Day 14. — 35 participants
N/A N=30 ReCell® Combined With Meshed Skin Graft in the Treatment of Acute Burn Injuries
Burns
Primary: Number of Participants With Confirmed Treatment Area Closure of RECELL-treated Wounds Compared to Control (Non-inferiority) — 24; 22; 2; 4 Participants
Phase 2 N=12 Study of EB-001 in Facial Scar Reduction
Mohs Surgery
Primary: Assessment of Visual Analog Scale (VAS) Change (Values From 0 (Worst) to 10 (Best)) — 0; 50 Percentage reporting improvement
N/A N=20 Treatment of Post-Surgical Scars With Traditional Ablative Er:YAG Versus Fractional Ablative Er:YAG
Post-Surgical Scars
Primary: Patient Observer Scar Assessment Scale (POSAS) — 17.69; 11.2; 15.2; 11.4 units on a scale — p=0.019
N/A N=33 Evaluation of the 755nm Alexandrite Laser for the Treatment of Scars
Scars
Primary: Photographic Evaluation of Scar Clearance — 1.82 score on a scale
Phase 2 N=42 Botulinum Toxin is a Potential Prophylactic Therapy for Minimizing Post-excisional Scarring (Allergan Botox Scar Study)
Post-operative Excessive Scarring
Primary: Modified Manchester Scar Scale (MMSS) Score — 8; 11.5 score on a scale
Phase 1 N=30 StrataGraft® Skin Tissue as an Alternative to Autografting Deep Partial-Thickness Burns
Skin Wound · Burns · Trauma-related Wound
Primary: Number of Participants With Wound Closure of the Treatment Sites at Three Months — 29; 29 Participants
N/A N=14 Assessment of Safety and Effectiveness of Biodegradable Temporizing Matrix in the Treatment of Deep Burn Skin Injuries
Burns
Primary: BTM 'Take' Rate — 95.22 percentage of BTM take per subject
Phase 3 N=71 StrataGraft® Skin Tissue in the Promotion of Autologous Skin Regeneration of Complex Skin Defects Due to Thermal Burns That Contain Intact Dermal Elements
Burn, Thermal
Primary: Percent Area of Treatment Sites Requiring Autografting by Month 3 — 4.33; 102.10 percentage of treatment sites — p=<0.0001
N/A N=51 Interventional Study to Evaluate the Appearance of Surgical Scars After Laser Therapy
Cicatrix · Carbon Dioxide Laser
Primary: Change in Vectra Measured Length V1 (Month 0)-V2 (Month 3) for Original Group; Visit 3 (Month 6) to Visit 4 (Month 9) for Crossover Group — 0.10; 0.03 mm
Phase 2 N=45 Burn Healing and Analgesia With Propranolol
Burns · Pain
Primary: Overall Pain Trajectory Slopes — -0.22; -0.16 Numeric Rating Scale Score Change/Day
N/A N=42 755nm Alex Laser for Treatment of Pigmented and Vascular Lesions and Scars
Benign Pigmented and Vascular Lesions and Scars
Primary: Clearance Based on Photographic Scale — 2; 2; 4; 7 Participants
N/A N=15 Evaluation of Antimicrobial Soft Silicone, Silver Containing, Foam Dressing, Mepilex Border Ag, in Second Degree Burns
Burns
Primary: Evaluate the Experience of Using Mepilex Border Ag ( a Silver Dressing) in Normal Clinical Practice — 9 burns healed
Phase 3 N=34 Effect of EGF With Silver Sulfadiazine Cream Compared With Silver Zinc Sulfadiazine Cream for Treatment of Burn Wound
Deep Partial Thickness Burn
Primary: Time of Healing by Monitoring Duration (Days) at the Beginning of Treatment and the Day of Completely Epithelialization (Complete Epithelialization Means no Open Wound…
N/A N=100 Comparison of Lasers in the Treatment of Scars
Scar
Primary: Scar Pain — 1.265; 1.181; 1.048; 1.084 units on a scale — p=0.0492
N/A N=8 An Investigation to Evaluate a New Donor Site Dressing in Surgical Burn Patients
Donor Site Complication
Primary: Percentage of Participants Who Had > 95 % Epithelialization at Day 10 — 0 percentage of participants
Phase 2 N=20 Cranial Electrotherapy Stimulation in Burned Patients
Post Traumatic Stress Disorders · Burns
Primary: Mean Post-Traumatic Stress Questionnaire-Military (PCL-M) Score — 53.8; 56.7; 48.8; 50.4 Score
Phase 3 N=175 A Study to Evaluate the Efficacy and Safety of NexoBrid in Subjects With Thermal Burns
Thermal Burns
Primary: Primary Endpoint: Number of Participants With Complete Eschar Removal. — 70; 1 Participants — p=<0.0001
N/A N=3 Indocyanine Green (ICG) and SPY Imaging for Assessment of Burn Healing
Burns
Primary: Perfusion of Burned Area — 200; 100; 205; 180 % perfusion compared to normal skin
N/A N=146 Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Scar · Skin Scarring · Skin Cancer
Primary: Cosmetic Outcome — 7.4; 6.6; 6.3; 6.00 score on a scale