Phase 4 N=52 Contralateral ReSTOR / Monofocal or Phakic Eye
Cataracts
Primary: Visual Acuity — -0.04; -0.01; 0.14; 0.18 LogMar
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=80 Quatera 700 vs. Centurion
Cataract
Primary: Central Corneal Thickness — 572.8; 565.6 microns
N/A N=114 Infant Aphakia Treatment Study (IATS)
Congenital Cataract
Primary: Visual Acuity — 0.80; 0.97 logMAR units — p=0.19
N/A N=30 AcrySof® Bilateral PanOptix(R) Spectacle Freedom and Patient Satisfaction Study
Cataract
Primary: Number of Participants Who Have Spectacle Independence — 27 Participants
Phase 4 N=34 Visual Function With Bilateral AcrySof® ReSTOR® Aspheric SN6AD1
Cataract
Primary: Binocular Visual Acuity at Distance, Near and Intermediate — 0.00; 0.13; 0.07; 0.00 LogMAR
Phase 4 N=76 Visual Function After Implantation of Bilateral AcrySoft ReSTOR Aspheric IOL
Cataract
Primary: Visual Acuity — 0.54; 0.06; 0.03; 0.04 logMAR
N/A N=40 Clinical Outcomes With Bilateral Implantation of Odyssey IOLs
Cataract
Primary: Visual Acuity at Distance (6m) logMAR — 0.00; -0.02; 0.02; 0.00 logMAR
Phase 4 N=79 Effect of Nepafenac on Post-operative Macular Swelling Following Uncomplicated Cataract Surgery
Cystoid Macular Edema
Primary: Central Macular Thickness (Difference in Mean Pre-post Changes by the Two Treatment Groups) — 2.78; 5.6 microns — p=0.7029
Phase 3 N=211 Clobetasol Propionate Ophthalmic Nanoemulsion 0.05% for the Treatment of Inflammation and Pain Associated With Cataract Surgery (CLOSE-1)
Cataract
Primary: Anterior Chamber Cell Grade — 67; 18 Participants
Phase 3 N=122 One-Piece Hydrophobic Acrylic Intraocular Lens in Subjects Undergoing Cataract Extraction
Aphakia · Cataract
Primary: Visual Acuity — 108 Participants
N/A N=442 Cerebrotendinous Xanthomatosis (CTX) Prevalence Study
Cerebrotendinous Xanthomatosis (CTX)
Primary: Number of Participants Who Had Positive Genetic Test Results — 4 Participants
Phase 3 N=78 A Randomized Study in Children Ages Birth Through Three Years Undergoing Unilateral Cataract Extraction With or Without Lens Replacement
Unilateral Cataract Extraction · Congenital Cataract
Primary: Intraoperative Pupil Diameter — 0.14; 0.20 millimeters*minutes
N/A N=162 Randomized Contralateral Clinical Trial With Single-piece (SN60WF) vs. Three Piece (MA60AC) AcrySof Intraocular Lenses (IOLs) on Development of Posterior Chamber Opacification (PCO).
Cataract
Primary: Posterior Capsule Opacification (PCO) — 0.18; 0.15 Units on a scale
N/A N=20 Cochlear Implantation in Pediatric Cases of Unilateral Hearing Loss
Hearing Loss, Unilateral
Primary: Change Over Time in the Ability to Perceive Single Words as Assessed by Consonant-Nucleus-Consonant (CNC) Word Recognition Testing — 1.4; 14.4; 28.2; 45.0 percentage of…
Phase 3 N=215 Clobetasol Propionate Ophthalmic Nanoemulsion 0.05% for the Treatment of Inflammation and Pain Associated With Cataract Surgery (CLOSE-2)
Cataract
Primary: Anterior Chamber Cell Grade — 38; 7 Participants
Phase 4 N=60 Visual Function After Bilateral Implantation of AcrySof® Toric
Visual Function
Primary: Uncorrected Visual Acuity (UCVA) — 0.06; 0.14 logMAR
Phase 3 N=156 Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
Cataract
Primary: Number of Participants With Summed Ocular Inflammation Score (SOIS) of Zero — 36; 23 participants
Phase 3 N=126 Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
Cataract
Primary: Number of Participants With Summed Ocular Inflammation Score (SOIS) of Zero — 28; 20 Participants
N/A N=15 ACRYSOF® Toric NATURAL T9 Intraocular Lens (IOL)
Bilateral Cataract
Primary: Number of Subjects Reporting Spatial Distortions Related to Intraocular Lens (IOL) Misalignment — 11; 2 Participants
N/A N=110 Infrared Choroidal Reflectance Camera for the Detection of Childhood Cataract
Childhood Cataract
Primary: Results of Red-reflex and Infrared-reflex Tests Compared to Gold Standard — 17; 54; 32; 7 eyes
Phase 4 N=94 No Drop Post-Op Cataract Surgery
Cataract
Primary: Best Corrected Visual Acuity (BCVA) (Pre-op) — .28 LogMar
Phase 2 N=91 Phase 2: VVN461 Ophthalmic Solution for Post -Operative Ocular Inflammation After Cataract Surgery
Inflammation
Primary: Anterior Chamber Cell: Categorical Cure — 18; 16; 6 Participants
N/A N=75 Monofocal IOL Visual Outcomes When Targeting Mini Monovision
Cataract · Presbyopia
Primary: Binocular Distance-corrected Intermediate (66 cm) Visual Acuity at 3 Months. — 0.19; 0.04 logMAR
N/A N=103 A Clinical Outcome Study of Two Multifocal Intraocular Lenses (IOL) in Cataract Patients
Cataracts
Primary: Binocular Distance Corrected Visual Acuity (logMAR) - Intermediate (60 cm) — 0.13; 0.09 logMAR
N/A N=100 Posterior Capsule Opacification and Frequency of Nd:YAG Treatment and of Two Microincision IOLs: Hoya iMics NY-60 vs Acrysof SN60WF
Capsule Opacification · Pseudophakia · Cataract
Primary: Posterior Capsule Opacification (PCO) — 3.0; 1.9 units on a scale (0-10)
N/A N=104 Posterior Capsule Opacification (PCO) Evaluation of the AcrySof SN60AT Lens vs. SN60WF Lens
Cataract
Primary: Posterior Capsule Opacification (PCO) — 11.58; 14.04 Percentage of PCO
N/A N=32 Phacoemulsification Versus Phacoemulsification With Micro-bypass Stent
Primary Angle-Closure Glaucoma · Primary Angle Closure Without Glaucoma Damage
Primary: Change in Intraocular Pressure Between Baseline and 1 Year — 15; 14.7 mmHg
Phase 4 N=118 Dropless vs. Standard Drops Contralateral Eye Study
Cataract
Primary: Change From Baseline (Preoperative Exam) in Macular Thickness — 12.34; 10.96; 9.84 Microns
N/A N=208 Visual Outcomes After Cataract Surgery: Multifocal AcrySof® IQ ReSTOR® Intraocular Lenses Versus Monofocal Intraocular Lenses
Cataract
Primary: Percentage of Participants Classified as Responders — 45.7; 2.1 percentage of participants
Phase 4 N=20 Intraoperative Dexamethasone Implant Improves Outcome of Cataract Surgery With Diabetic Macular Edema
Macular Edema, Cystoid · Vision Disorders · Diabetic Macular Edema
Primary: Change in the Central Macular Thickness — 85.67; -18.22 Microns