Phase 2 N=224 Preventing Complications in Cleft Palate Repair With Antibiotics
Cleft Palates
Primary: Number of Participants With Fistula or Delayed Wound Healing Following Palatoplasty — 3; 2; 18; 21 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=131 Acellular Dermal Matrix in Primary Palatoplasty
Cleft Palate
Primary: Fistula Formation — 1; 8 participants
Phase 2 N=30 Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair
Cleft Lip · Scarring · Cleft Palate
Primary: Hypertrophic Scarring (HTS) as Assessed by Score on the Manchester Scar Scale (MSS) Rated by Blinded Plastic Surgeons — 7; 9 score on a scale
N/A N=5 Use of Mesenchymal Stem Cells for Alveolar Bone Tissue Engineering for Cleft Lip and Palate Patients
Cleft Lip and Palate
Primary: Amount of New Bone Mass Formed — 89 percentage of bone formation
N/A N=45 Efficacy of Oral Versus Intravenous Acetaminophen for Primary Pediatric Cleft Palate Repair
Cleft Palate
Primary: Opioid (Fentanyl and Morphine) Consumption
N/A N=60 Study to Evaluate Efficacy, Safety and Injection Technique of Restylane Lip Volume and Restylane Lip Refresh
Injection Techniques
Primary: GEIS (Global Esthetic Improvement Scale) Assessed by the Subject at Week 8 After Treatment — 86.2; 86.7 percentage improved subjects
N/A N=106 Using Dexpanthenol Cream to Prevent Lip Corner Cracks in Children After Tonsil/Adenoid Surgery
Cheilitis, Angular · Postoperative Complications · Adenotonsillar Hypertrophy
Primary: Incidence of Angular Cheilitis — 5; 22; 46; 28 Participants
N/A N=202 RHA® 3 Versus Restylane-L® for Lip Augmentation
Lip Augmentation · Lip
Primary: Change in TLFS Score (Teoxane Lip Fullness Scale) Between Baseline and Week 12 After Last Treatment of RHA®3 Versus Control Device, as Assessed by the BLE — 1.0; 0.8…
Phase 4 N=37 Assessment and Augmentation of Lip Appearance in Specific Study Populations
Lip Aging · Lip Augmentation · Lip
Primary: Change in Lip Vessel's Thickness — 0.833; 0.360 µm
N/A N=62 Safety and Effectiveness of Juvéderm® Ultra Lip Injectable Gel for Lip Enhancement
Lip Enhancement
Primary: Investigator Assessment of the Subject's Overall Lip Fullness on the 4-point Lip Fullness Scale — 93.2 percentage of responders
N/A N=86 Orthodontic Patient Experience of Intraoral Scans Versus Alginate Impressions
Orthodontic Patient Experience
Primary: Orthodontic Patient Comfort — 9.2; 7.7 score on a scale — p=0.0006
N/A N=31 A Speech Recognition Application as a Communication Aid for Acute and Critical Care Patients With Tracheostomies
Tracheostomy · Communication · Acute/Critical Illness
Primary: Number of Participants Using SRAVI at Least Once — 31 Participants
N/A N=66 Transcranial Electrical Stimulation for mTBI
Mild Traumatic Brain Injury (mTBI) · Post-traumatic Stress Disorder
Primary: Change in Abnormal Magnetoencephalography (MEG) Slow-Waves (1-4 Hz) Activity — 1.8; 0.2; 0 units on a scale — p=0.01
Phase 2 N=13 Short-term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz Syndrome
Smith-Lemli-Opitz Syndrome
Primary: Hyperactivity Sub-scale of the Aberrant Behavior Checklist-Community (ABC-C). — 8.6; 8.6 units on a scale — p=1.0
N/A N=44 Expression of Angiogenic Biomarkers During Healing of Intra-Oral Soft Tissue Engineered Grafts
Gingival Recession
Primary: Differences in Angiogenic Biomarkers — 0.51; .69; 1.04; .67 ng/mL