N/A N=99 A Study of Octave System for Improving Lines and Wrinkles of the Décolleté
Décolleté Wrinkles
Primary: Percentage of Treated Subjects With Improvement in Lines and Wrinkles of the Décolleté at Day 90 — 62.2 percentage of subjects
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=117 Investigation of the Effectiveness and Safety of MRZF111 in the Treatment of Décolleté Wrinkles
Décolleté Wrinkles
Primary: Responder Rate for Décolleté Wrinkles According to the Merz Aesthetics Scale (MAS)-At Rest Scale as Assessed by the Blinded Live Rater — 71.8; 83.7; 73.5 percentage of…
N/A N=152 Evaluation of the Effectiveness and Safety of Diluted RADIESSE® in the Treatment of Décolleté Wrinkles
Décolleté Wrinkles
Primary: Percentage of Responders on Merz Aesthetic Scale (MAS) Décolleté Wrinkles - at Rest at Week 24 — 71.2; 6.3 percentage of subjects
N/A N=30 An Open-label Study of Poly-l-lactic Acid for Correction of Wrinkles in the décolletage Area
Wrinkles in Decolletage
Primary: Percentage of Responders on the Galderma Décolletage Scale (GDS), as Assessed Live by the Treating Investigator, at Month 9 — 93.8; 78.6 percentage of Participants
N/A N=49 Prospective Pellevé™ Neck Wrinkle Study
Facial and Neck Rhytides
Primary: Change in Neck and Facial Wrinkles Using the Fitzpatrick Wrinkle Assessment — 74 percentage of participants
N/A N=125 Evaluation of the Ulthera System for the Treatment of the Decolletage
Chest Wrinkles
Primary: Percentage of Participants With a Reduction in Chest Wrinkles at 90 Days Post Treatment — 69.9; 15.9; 14.2 percentage of participants
N/A N=25 Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles
Rhytides · Wrinkle
Primary: Subject Satisfaction — 2.8 score on a scale
N/A N=68 Reducing Wrinkles Around the Eyes Using the Ulthera® System
Periorbital Wrinkles
Primary: Overall Improvement in Periorbital Wrinkles and Rhytids Around the Eyes — 47; 50 percentage of participants improved
N/A N=35 Efficacy and Tolerability of SkinPen on Male and Female Subjects' Wrinkles of the Neck
Wrinkles
Primary: Assessment of Wrinkle Severity Using the Lemperle Wrinkle Assessment Scale — 3.31; 2.45 Score on a Scale — p=<0.01
Phase 3 N=42 Cryo-Touch II for the Treatment of Wrinkles
Facial Wrinkles
Primary: Number of Participants With Effectiveness and Safety Success — 30; 41 participants
N/A N=15 Clinical Evaluation of Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles
Rhytides · Wrinkle
Primary: Change in Facial Wrinkles at 12 Weeks Post Final Treatment Compared to Baseline — -0.10 units on a scale
N/A N=72 Proof of Concept Anti-ageing Clinical Study in Healthy Subjects
Skin Aging
Primary: Change From Baseline in Ra (a dermaTOP Parameter), of Test Product Treated Versus (vs.) Untreated Side at Day 29 — -1.90; -0.12 Micro meter (µm) — p=0.0638
N/A N=40 Safety and Efficacy of Single Therapy Versus Double and Triple Therapy of the Pellevé™ Wrinkle Treatment System for the Treatment of Moderate Facial Wrinkles
Appearance of Facial Wrinkles
Primary: Fitzpatrick Wrinkle Assessment — 1.0; 1.5; 1.1 units on a scale, change in Fitzpatrick
Phase 3 N=121 Clinical Trial to Assess Efficacy, Safety and Tolerability of Botulinum Toxin A (Xeomin®) in Treatment of Expression Wrinkles in the Upper Third of the Face
Skin Aging
Primary: Treatment Success — 89.08 % of participants
Phase 4 N=30 Emervel for the Correction of Lower Face Wrinkles & Folds
Nasolabial Folds · Marionette Lines · Wrinkles
Primary: Number of Subjects With Naturalness of Expression in Motion (2D Video) — 30 Participants
N/A N=24 Confirmatory Study: Assessing the Efficacy and Safety of the AcusMu Microneedle Patch in Treating Periorbital Wrinkles
Wrinkle
Primary: Proportion of Participants With Improvement in Periorbital Wrinkles From Baseline — 10; 2; 8; 2 Participants
N/A N=66 Reliability of the Facial Wrinkle Scale in Japanese Subjects
Facial Rhytides
Primary: Inter-rater Reliability of Assessment of Facial Lines Using the 4-Point Facial Wrinkle Scale (FWS-A) — 0.653; 0.637; 0.647; 0.654 Kappa statistics
N/A N=149 Safety and Effectiveness of Sculptra Aesthetic for Correction of Cheek Wrinkles
Cheek Wrinkles
Primary: Responder Rate Based on the Blinded Evaluator's Live Assessment of the Galderma Cheek Wrinkles Scale (GCWS) at Rest at Month 12 — 26.1; 71.6 percentage of participants…
Phase 3 N=118 Multicenter Study of the Safety and Effectiveness of Dermal Filler, Belotero®.
Facial Wrinkles
Primary: Adjusted (LS) Mean Change From Baseline in Wrinkle Severity Rating Scale (SRS) Score of Each Nasolabial Fold (NLF) as Determined by the Blinded Evaluator at Week 12…
N/A N=80 A Prospective, Open Label Study Evaluating JUVÉDERM® VOLBELLA With Lidocaine Treatment for the Correction of Skin Depressions in the Infra-orbital Area
Infra-orbital Skin Depressions
Primary: Percentage of Subjects With a ≥1 Grade Improvement From Baseline in Infra-Orbital Area on the Allergan Infra-Orbital Rating Scale (AIRS) on the Right and Left Side — 99…
N/A N=20 Radio Frequency Microneedling for Suprapatellar Skin
Skin Laxity
Primary: Photographic Knee Laxity and Texture Evaluation — 1.87; 2.02 score on a scale
N/A N=10 Fractional Radiofrequency for the Treatment and Reduction of Acne Scars and Wrinkles
Acne Scars - Mixed Atrophic and Hypertrophic · Wrinkle
Primary: Overall Wrinkle Improvement Assessed by the Fitzpatrick Wrinkle and Elastosis Scale (FWES) at 12 Weeks Post-Final Treatment — 5.97; 5.78 units on a scale
N/A N=20 Evaluation of the Safety and Efficacy of the Pico Laser With a Specialized Lens Array for the Treatment of Wrinkles
Wrinkles
Primary: Photographic Evaluation of Wrinkle Severity at Baseline — 5.7 score on a scale
Phase 3 N=26 Lateral Canthal Rhytides With Medium Depth Chemical Peel With or Without Pretreatment With Botulinum Toxin A
Wrinkles
Primary: Posttreament Results of Chemical Peel if Botox A is Added as Pre-treatment — 1; 2 Units on a wrinkle severity scale — p=.002
N/A N=58 Clinical Study to Evaluate the Correction of Wrinkles and Folds and Safety of YVOIRE Classic Versus Restylane in Nasolabial Fold Intradermal Injection
Temporary Correction of Wrinkles
Primary: Average of Wrinkle Severity Rating Scale (WSRS) Score Evaluated by the Evaluating Investigator at Week 26 (Visit 7) After the Final Treatment With the Investigational…
N/A N=62 Princess® VOLUME Lidocaine for the Correction of Nasolabial Folds
Nasolabial Fold, Hypoplastic
Primary: NLF-SRS Grade of Nasolabial Folds Change — -1.50 score on a scale
N/A N=50 Thermage CPT for Treatment of Facial and Neck Laxity
Skin Aging
Primary: Improvement in Laxity — 0.6; 1.0; 0.9; 1.3 units on a scale
N/A N=51 Clinical Study Evaluating the Safety and Effectiveness of The Tixel Fractional System in The Treatment of Periorbital Wrinkles
Wrinkle · Periorbital · Tixel 2
Primary: Percentage of Participants With Safety Adverse Events — 3.92 Percentage of Participants
N/A N=20 Evaluating the Safety and Efficacy of the Pico Laser With a Specialized Lens Array for the Treatment of Wrinkles
Wrinkles
Primary: Photographic Evaluation of Wrinkle Severity at Baseline — 5.25 score on a scale
N/A N=110 Saypha® Volume LIdocaine in Nasolabial Folds
Moderate to Severe Nasolabial Folds
Primary: Responder Rate in Reduction of Nasolabial Folds — 34; 39; 73 Participants