30 closest matches · ranked by relevance
Partial-Onset or Primary Generalized Tonic-Clonic Seizures
Primary: Percentage of Participants With Treatment Emergent Adverse Events (AEs) and Treatment Emergent Serious Adverse Events (SAEs) for Total Group of Participants - Core Phase…
Partial Seizures
Primary: Percent Change in Partial Seizure Frequency Per Week From Baseline to Visit 6 — 24.24 percent change
Epilepsies, Partial
Primary: Number of Treatment-Emergent Adverse Events (AEs) by Severity: Double-blind Treatment — 0; 2; 2; 4 adverse events
Epilepsy · Partial Seizures
Primary: Change From Baseline in Partial Seizure Frequency Per Week Over the 14-weeks Treatment Period — 43.21 Percent reduction
Partial Onset Seizures
Primary: Log Transformed 24-Hour Seizure Rate for All Partial Onset Seizures During the Double-Blind Treatment Phase — 1.69; 1.15; 1.58 seizures per 24 hours — p=0.4606
Epilepsy
Primary: Change in Partial Onset Seizure (POS) Frequency Per 28 Days From Baseline to the Maintenance Period — -1.55; -3.05 Seizures per 28 days — p==0.0003
Epilepsies, Partial
Primary: Number of Participants With Adverse Events (AE). — 14; 13; 11; 9 Participants
Epilepsy, Partial Seizures · Epilepsy, Primary Generalized Tonic-Clonic Seizures
Primary: Number of Participants With Treatment Emergent Adverse Events (AEs), Treatment Emergent Serious Adverse Events (SAEs), Treatment Related AEs and Treatment Related SAEs…
Epilepsies, Partial
Primary: Response Ratio of Gabapentin in Japanese Pediatric Patients With Partial Seizures — -0.158 ratio
Childhood Absence Epilepsy · Petit Mal Epilepsy · Epilepsy
Primary: Number of Participants With Freedom From Treatment Failure at 16-20 Weeks of Double Blind Therapy — 81; 43; 85 Participants — p=<0.001
Epilepsy, Partial
Primary: Percentage Change (Reduction) of Partial (Type I) Seizure Frequency Per Week From Baseline Over Time During Treatment Period. — 51.06; 68.87 percent reduction in…
Partial Epilepsy in Children and Adolescents
Primary: Change From Baseline in Seizure Frequency — 62.0; 36.6 seizures/month — p=0.2490
Epilepsies, Partial
Primary: Number of Participants With Treatment-Emergent Adverse Events (All Causalities and Treatment-Related) — 58; 13; 2; 0 Participants
Epilepsy, Partial Seizures
Primary: Log-Transformed 28-Day Seizure Rate For All Partial Onset Seizures During Baseline Phase — 3.27; 3.19; 3.18 Seizures per 28 days
Central Nervous System
Primary: Apparent Clearance (CL/F) of Perampanel [Core Study] — 0.732; 0.956; 1.73; 1.92 Liter per hour
Epilepsy With Partial On-set Seizures
Primary: The Number of Subjects Completing 24 Weeks Adjunctive Therapy During Maintenance Phase — 36; 37 participants
Partial Epilepsy
Primary: Change From Baseline in Power of Attention Score to the End of the Double Blind (DB) Period — 111.085; 59.122 Milli seconds (ms) — p=0.700
Partial Seizures · Epilepsies, Partial
Primary: Log Transformed (Loge) 28-day Seizure Rate for All Partial Onset Seizures During the Double-blind Treatment Phase — 2.24; 2.33; 2.32; 1.84 ln (seizures per 28 days)…
Partial Onset Seizures
Primary: Percent Change in Partial Onset Seizure Frequency Per 28 Days From Baseline to the Double-blind Phase, by Treatment Group — -2.85; 14.82 percentage change per 28 days
Epilepsy · Generalized Tonic-clonic Seizures
Primary: The Percent Change From the Combined Baseline (4-week Retrospective Baseline and 4-week Prospective Baseline) in the Generalized Tonic-clonic Seizure Frequency Per Week…
Epilepsy; Paediatric Partial Onset Seizures
Primary: Percentage of Participants With a Decrease From Baseline in 28-day Seizure Frequency of =50%(Responder) in the Maintenance Period(LOCF) — 31; 50 Percentage of Participants
Epilepsy
Primary: Percentage of Participants With Treatment-emergent Adverse Events (TEAEs) During the Study — 94.4; 93.3; 93.6; 92.3 percentage of participants
Generalized Tonic Clonic Seizures
Primary: Log-transformed (Log) 28-day Seizure Rate for All Primary Generalized Tonic-Clonic (PGTC) Seizures During 12-Week Double-Blind Treatment Phase — 1.17; 1.13; 1.14 Seizure…
Partial Seizures
Primary: Proportion of Participants With Response to Treatment — 0.59; 0.59 proportion of participants
Epilepsy
Primary: Change From Baseline in Weight Z-score up to Month 1 — -0.112; -0.014 Z-score
Epilepsy
Primary: Responders: Number of Subjects With a 50% or Greater Reduction in Seizure Frequency — 138; 44; 17 participants
Epilepsy
Primary: Mean Trough Plasma Concentration at 3rd Level for Age Range ≥1 Month to <2 Years — 0.825 ug/mL
Partial Epilepsy
Primary: Percent Change From Baseline in Partial-onset Seizure Frequency Per 28 Days — 55.6; 21.5 percent seizure reduction — p=<0.0001
Epilepsy
Primary: Percentage of Participants With Treatment-emergent Adverse Events (TEAEs) — 77.2 percentage of participants
Epilepsy With Partial-onset Seizures
Primary: Change in Average Daily Frequency (ADF) of Electrographic Partial-onset Seizures From End-of-Baseline (EOB) Period Video-EEG to End-of-Maintenance (EOM) Period Video-EEG…