N/A N=16 Eustachian Tube Dysfunction Assessment
Eustachian Tube Dysfunction
Primary: Latency Between mLVP and mTVP Signals — 127.26 Time in milliseconds
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=323 Study of Safety and Efficacy for the Eustachian Tube Balloon Catheter
Eustachian Tube Dysfunction
Primary: Primary Efficacy Analysis: Number of Randomized Subjects With Tympanogram Normalization at 6 Weeks — 73; 10 Participants
Phase 2 N=25 Effect of Simethicone on Eustachian Tube Dysfunction
Otitis Media
Primary: Fraction of Middle Ear (ME) Pressure Equilibrated (FGE) — 0.17; 0.24; 0.19; 0.23 ratio — p==0.93
N/A N=60 XprESS Eustachian Tube Dilation Study
Eustachian Tube Dysfunction
Primary: Change From Baseline in Mean Overall ETDQ-7 Scores — -2.9; -0.6 units on a scale — p=<0.0001
Phase 3 N=91 Short Term Relief of Eustachian Tube Dysfunction and Serous Otitis Media Using Intranasal Steroid Sprays
Otitis Media, Serous · Negative Middle Ear Pressure · Rhinitis
Primary: Number of Subjects With Complete Normalization of Abnormal Tympanometry, Regardless of Additional Treatment — 7; 12 participants — p=0.18
N/A N=30 SinuSonic for ETD and Facial Pain: Acoustic Vibration + Oscillating Expiratory Pressure
Eustachian Tube Dysfunction · Facial Pain
Primary: Eustachian Tube Dysfunction (ETD) Symptom Visual Analog Scale (VAS) - Total Score — 59.6 score on a scale
Phase 3 N=53 Evaluation of the Tympanostomy Tube Delivery System
Otitis Media With Effusion · Acute Otitis Media
Primary: Safety of Tympanostomy Tube (TT) Delivery System — 0.0 percentage of ears
N/A N=25 Singapore Tympanostomy Tube Delivery System Study
Otitis Media
Primary: Percentage of Ears Treated Successfully With the TTDS in the Absence of Acute Intraprocedural Adverse Events. — 94.6 percentage of ears
N/A N=16 Clinical Study of the Tympanostomy Tube Delivery System
Otitis Media With Effusion
Primary: Device Success — 21 devices
Phase 4 N=41 Treatment of Clogged Tympanostomy Tubes: An Off-Label Use of Dornase Alfa (Pulmozyme®)
Otitis Media
Primary: Patency of the Tympanostomy Tube at the Day-14 Visit. — 8; 11; 15; 12 Ear — p=.36
Phase 3 N=385 Safety and Efficacy of EXE844 Otic Suspension in Otitis Media at Time of Tympanostomy Tube Insertion (OMTT)
Otitis Media With Effusion in Children · Otitis Media Recurrent
Primary: Percentage of Subjects With Sustained Clinical Cure at Day 8 — 76.2; 71.8; 56.8 percentage of participants
N/A N=70 Tympanostomy Tube Placement in Children in the Office (Inova Study)
Otitis Media
Primary: Number of Participants With Procedural, Serious, and Device-Related Adverse Events — 0 participants
Phase 3 N=356 Safety and Efficacy of EXE844 Otic Suspension in Otitis Media at Time of Tympanostomy Tube Insertion (OMTT) - Study 2
Otitis Media With Effusion in Children · Otitis Media Recurrent
Primary: Percentage of Subjects With Sustained Clinical Cure at Day 8 — 77.1; 75.5; 65.3 percentage of participants
N/A N=85 inVENT-In-Office Study
Otitis Media
Primary: Percentage of Subjects With In-office Tube Placement Procedure Success — 93.2 Percentage of Subjects
Phase 3 N=266 OTO-201 for the Treatment of Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement
Otitis Media With Effusion
Primary: Percentage of Participants Who Were Treatment Failures — 24.6; 44.8 percentage of treatment failures
Phase 3 N=266 OTO-201 for the Treatment of Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement
Otitis Media With Effusion
Primary: Percentage of Participants Who Were Treatment Failures. — 21.3; 45.5 percentage of treatment failures
Phase 3 N=33 Open-Label Study of OTO-201 for Middle Ear Effusion Evaluating Trans-Tympanostomy Tube Administration
Bilateral Middle Ear Effusion
Primary: Otoscopic Examination: Auricle and Meatus — 1 ears
Phase 3 N=370 In-Office Tympanostomy Tube Placement in Children (OTTER)
OME - Otitis Media With Effusion · AOM - Acute Otitis Media
Primary: Procedural Success: — 103; 91 Participants
N/A N=109 Study of the Hummingbird TTS™ Tympanostomy Tube System
Otitis Media
Primary: Percentage of Procedures Converted From Sedation to General Anesthesia — 12.8 percentage of procedures converted
N/A N=29 Acclarent Tympanostomy Tube Delivery System for the Treatment of Patients Requiring Tympanostomy Tube Insertion
Otitis Media
Primary: Ear Outcome Success — 21 ears
N/A N=199 Hummingbird TTS Ear Tube Delivery Study
Otitis Media
Primary: Percentage of Ears in Which an Ear Tube Was Successfully Delivered Across the Tympanic Membrane — 393 Ears
N/A N=250 Efficacy of Tympanostomy Tubes for Children With Recurrent Acute Otitis Media
Acute Otitis Media
Primary: The Rate of Occurrence of Acute Otitis Media (AOM) Episodes Per Child-Year — 1.48; 1.56 Occurrences per child-year — p=0.66
N/A N=42 inVENT-visIOn Study
Otitis Media
Primary: Number of Subjects With Procedural, Serious and Device-related Adverse Events. — 0 subjects
N/A N=65 Assessment of an Endotracheal Tube Securement Device
Respiratory Insufficiency
Primary: Prevention of Damage and/or Occlusion of Endotracheal (ET) Tube During Use — 0; 1 participants
N/A N=25 Tympanoseal (Tympanic Membrane Device) Clinical Study
Tympanic Membrane Perforation
Primary: Number of Serious Adverse Events — 0 Serious Adverse Event
N/A N=90 Tracheal Palpation of Sliding Cuff to Assess Endotracheal Tube Location
Anesthesia Intubation Complication
Primary: Sore Throat — 1.5; 0.6 units on a scale — p=0.04
N/A N=72 Comparison Between Etview Tracheoscopic Ventilation Tube - TVT to Standard Endotracheal Intubation
Endotracheal Intubation
Primary: In the Present Study we Will Compare the Performance Parameters of Intubation Using Etview Tracheoscopic Ventilation Tube - TVT to the Standard Tube
Phase 2 N=30 Adult Study to Evaluate Placement of Tympanostomy Tubes In-office (ADEPT)
Barotrauma;Ear · OME - Otitis Media With Effusion · AOM - Acute Otitis Media
Primary: Subject-reported Pain Score Following Tube Delivery System (TDS) Tube Placement Using the Visual Analogue Scale (VAS) by Subject Compared to a Performance Goal. — 9.4…
N/A N=100 No Post Intubation Laryngeal Symptoms
Sore-throat · Dysphonia · Dysphagia
Primary: Sore Throat on a Scale From 0 (no Sore Throat) to 10 (Worst Possible Sore Throat) — 1.85; 1.9; 1.1; 1.62 score on a scale — p=0.03
N/A N=84 Endotracheal Tube Intracuff Pressure and Leak
Otolaryngological Surgery
Primary: Changes in the Intracuff Pressure — 3 cmH2O