N/A N=99 Safety and Effectiveness of an Auricular Spray
Excessive Ear Wax
Primary: Skin Irritation — 0.22; 0.20; 0.13; 0.11 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=19 Evaluation of a Novel Product for the Removal of Impacted Human Cerumen (Earwax)
Cerumen Impaction of Both Ears
Primary: Percentage of Ears That Showed Change in Visualization of the Tympanic Membrane (Ear Drum) Following 15 or 30 Minutes of Using the Test Product — 53.3; 85.7 percentage…
Phase 3 N=179 Efficacy and Safety Study of Miconazole Oil Versus Vehicle on Fungal Infection of the Ear Canal (Otomycosis)
Otomycosis
Primary: Percentage of Subjects With Therapeutic Cure — 14; 11; 53; 53 Participants
Phase 3 N=112 Phase III Efficacy and Safety Study of Miconazole Oil for Otomycosis
Otomycosis
Primary: Number of Participants With Clinical Cure — 19; 18 Participants
Phase 3 N=499 Comparative Efficacy and Safety of Ciprofloxacin 0.3% and Dexamethasone 0.1% in Acute Otitis Externa
Acute Otitis Externa
Primary: Number of Participants With Clinical Cure of AOE — 190; 191 Participants
Phase 3 N=135 Clinical Study to Assess the Efficacy and Safety of DF277 Compared to Placebo in the Treatment of Otic Eczema
Otic Eczema
Primary: Analysis of the Itching Change at the End of Treatment. — -1.63; -1.25 units on a scale
N/A N=30 Clinical Performance Evaluation of 3D Ear Canal Scanning Technology
Ear Mold Impression Procedure
Primary: Elapsed Time in Minutes to Complete Bilateral Ear Impressions — 8.15; 6.28 Minutes
N/A N=119 Ear Drops for Children With Otitis Media
Acute Otitis Media
Primary: Resolution of Otitis Media Symptoms — 14.2; 16.5; 7.5; 14.1 units on a scale — p=.002
Phase 2 N=75 OTO-201 for the Treatment of Otitis Externa
Otitis Externa
Primary: Otoscopic Examination: Tympanic Membrane — 6; 8; 8 Participants
Phase 4 N=41 Treatment of Clogged Tympanostomy Tubes: An Off-Label Use of Dornase Alfa (Pulmozyme®)
Otitis Media
Primary: Patency of the Tympanostomy Tube at the Day-14 Visit. — 8; 11; 15; 12 Ear — p=.36
N/A N=30 Investigations of Ear Tip Performance, Perceptions, and Experiences
Hearing Aids
Primary: Real Ear Measures — 61.23; 60.23; 60.5; 64.53 dB SPL — p=<0.05
Phase 3 N=326 Xylitol Syrup for the Prevention of Acute Otitis Media in Otitis-prone Children
Acute Otitis Media
Primary: Effectiveness of Viscous-adherent Xylitol Syrup in Reducing Episodes of Clinically-diagnosed Acute Otitis Media — 66.9; 63.3 percentage of particpants — p=0.6
Phase 2 N=65 Dose-Ranging Study for Miconazole Oil for Treatment of Otomycosis
Otomycosis
Primary: Primary Efficacy Endpoint — 1; 3; 1 Participants
Phase 3 N=262 Phase 3 Study of OTO-201 in Acute Otitis Externa
Acute Otitis Externa · Swimmer's Ear
Primary: Number of Subjects Considered a Clinical Cure at Day 8 — 91; 63 Participants
Phase 2 N=69 A Study of DPK-060 to Investigate Clinical Safety and Efficacy in Patients With Acute External Otitis
Acute Otitis Externa
Primary: Adverse Events (AEs) — 10; 3; 6; 1 participants