30 closest matches · ranked by relevance
Fragile X-Associated Tremor/Ataxia Syndrome · Fragile X Premutation Carriers
Primary: Change From Baseline in Executive Functioning as Measured by the Behavioral Dyscontrol Scale II (BDS-II) — 17.44; 16.12; 15.66; 15.72 units on a scale
Fragile X-associated Tremor/Ataxia Syndrome
Primary: California Verbal Learning Test II (CVLT2) Trial 1-5 Free Recall Total Raw Score — 34.0; 33.5 score on a scale
Fragile X Tremor/Ataxia Syndrome
Primary: FXTAS Rating Scale Score — 45.8 score on a scale
Fragile X Syndrome · Autism Spectrum Disorders
Primary: Clinical Global Impression- Severity Scale (CGI-S) — 7.0 units on a scale
Fragile X Syndrome
Primary: Clinical Global Impression-Improvement (CGI-I) — 3.5 units on a scale
Fragile X Syndrome
Primary: Contingency Naming Test (CNT) Performance Score — 37.05; 40.50; 66.94; 61.56 correct responses per minute
Fragile X Syndrome
Primary: Change From Baseline of ABC Irritability Subtest Score at 8 Weeks — -14.37 units on a scale
Fragile X Syndrome
Primary: Aberrant Behavior Checklist — 7.1; 15.6; 9.6; 7.6 units on a scale
Fragile X Syndrome
Primary: Safety and Tolerability - Number of Treatment-Emergent Adverse Events — 2; 1; 1; 3 Number of Adverse Events
Fragile X Syndrome
Primary: Eye Contact/Gaze During 10 Minute Social Challenge Task — 15.4; 20.9; 17.0 eye contact/gaze events per 10 minutes
Fragile X Syndrome
Primary: Change From Baseline in Behavioral Symptoms of Fragile X Syndrome Using the Aberrant Behavior Checklist-Community Edition (ABC-CFX) Total Score in Stratum I Patients…
Fragile X Syndrome
Primary: Change in EEG Relative Gamma Power — 0.0024; -0.0077; -0.0039; 0.0019 percent of power in gamma frequencies
Fragile x Syndrome
Primary: Clinical Global Impression-Improvement (CGI-I) Scale — 3.4; 3.5 Scores on a scale — p=0.4475
Fragile X Syndrome
Primary: Aberrant Behavior Checklist Irritability Subscore — -5.1; -5.3 Points on a scale — p=0.05
Fragile X Syndrome
Primary: Change in Weighted Child Intentional Communication Score — 0.14; 0.04 log10(scores on a scale) — p=0.1587
Fragile X Syndrome
Primary: Clinical Global Impressions Improvement Scale as Determined by the Treating Clinician — 3.7; 3.8 score on a scale
Fragile X Syndrome (FXS)
Primary: Number of Participants With Treatment Emergent Adverse Events (TEAE) — 0; 0; 0; 1 participants
Fragile X Syndrome
Primary: Clinical Global Impression Scale (CGI) — 2.49; 2.97 units on a scale
Fragile X Syndrome · Genetic Diseases
Primary: Expressive Language Sample Composite Score in the Home — 39.63; 42.47 score on a scale
Fragile X Syndrome
Primary: Change in Mullen Scales of Early Learning - Expressive Language Raw Score — 19.3; 21.3; 21.3; 25.04 units on a scale
Fragile X Syndrome · FXS · Fra(X) Syndrome
Primary: Number of Participants With Treatment-Emergent Adverse Events (TEAEs) — 11; 8 Participants
Friedreich Ataxia
Primary: Change From Baseline in the Inverse Time to Complete the 9-Hole Peg Test (9-HPT-1) — 0.00038; -0.00017; -0.00032 1/seconds — p=>0.999
Friedreich Ataxia
Primary: Change in Whole Blood Frataxin Levels — -1.5 percentage of baseline frataxin level — p=0.027
Fragile X Syndrome (FXS)
Primary: Decisional Capacity - Understanding Score — 74.4; 75.1 percentage of understanding — p=0.89
Fragile X Syndrome
Primary: Aberrant Behavior Checklist-Community Fragile X Factor Structure (ABC-C FXS) Social Avoidance Subscale - Full Analysis Set — -2.68; -2.29 change in score — p=0.321
Friedreich's Ataxia
Primary: Change From Baseline in Friedreich Ataxia Rating Scale (FARS) Composite Score — 55.0 score on a scale — p=0.336
Friedreich Ataxia
Primary: Creatine Rephosphorylation Rate Post Exercise — 0.024; 0.029; 0.022; 0.029 pH per second — p=0.9133
Spinocerebellar Ataxias · Tai Chi
Primary: Scale for the Assessment and Rating of Ataxia(SARA) — 11.5; 9 score on a scale
Familial Amyloid Polyneuropathy
Primary: Percentage of Participants With Response to Treatment as Measured by Neuropathy Impairment Score - Lower Limb (NIS-LL) at Month 18 — 45.3; 29.5 percentage of participants
Friedreich Ataxia
Primary: Change in mFARS (Modified Friedreich's Ataxia Rating Scale) Score — 2.9; 4.9; 7.7; 2.2 units on a scale