30 closest matches · ranked by relevance
Healthy Participants
Primary: Cohort 1: Number of Participants With Treatment Emergent Adverse Events (TEAEs) — 5; 8; 6; 8 Participants
Healthy Participants
Primary: Number of Participants Reporting Treatment-Emergent Adverse Events (TEAEs) — 1; 2; 3; 2 Participants
Skin Diseases
Primary: Fold Change in Long Chain Fatty Acids — 1; 0.76 Fold Change in long chain fatty acids
Healthy
Primary: Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve From Zero to Infinity (AUC[0-∞]) of LY3484356 (Cohort 1) — 1810; 4350 nanogram*hour per milliliter…
HIV/AIDS
Primary: Average Tenofovir Diphosphate Concentrations in Mixed Rectal Cells During the Early (Low Estradiol) Follicular Phases of the Menstrual Cycle. — 406.14 fmol/million cells
Urinary Tract Infection
Primary: Proanthocyanidin A2 — 0.6; 0.20 ng/mg creatinine
Healthy Participants
Primary: Percentage of Total Radiocarbon (14C) Excreted in Urine — 11.9; 20.7 Percentage of 14C in urine
Healthy
Primary: Area Under the Plasma Concentration-time Profile From Time 0 Extrapolated to Infinite Time (AUCinf) of PF-06821497 — 3302; 3375; 3479; 11220 ng*hr/mL
Healthy Participants
Primary: The Maximum Observed Concentration of Nirmatrelvir in Breast Milk Over the Dosing Interval — 1904 Nanograms / milliliter (ng/mL)
Weight Gain · Healthy Subjects · Obesity
Primary: Proportion of n-6 HUFA in Total HUFA (%n-6 in HUFA) — 80.0; 81.3; 80.5 Percentage of total HUFA
Healthy Participants
Primary: Number of Participants With Treatment Emergent Adverse Events (TEAEs) — 1; 2; 1; 2 Participants
Healthy
Primary: Baseline Corrected Area Under the Concentration-Time Curve From Zero to Last Quantifiable Concentration (AUC 0-t,Adj) for Follicle-Stimulating Hormone (FSH) — 3187.4…
Healthy
Primary: The Mean (SD) Amount of [14C] Recovered in Urine, as a Percent of the Total [14C] Dose Administered — 25.2 percentage of dose
Healthy Volunteers · Adult · Pharmacokinetics
Primary: Area Under the Plasma Concentration-Time Profile From Time Zero Extrapolated to Infinite Time (AUCinf) of Ritlecitinib — 389.1; 398.3; 378.0; 387.8 nanogram*hour per…
Healthy · Premature Ovarian Failure
Primary: Follicle Stimulating Hormone Stimulated Serum Inhibin B Levels. — 50.7; 48.8; 96.6; 47.7 participants
Hair Removal
Primary: Percent of Participants Correctly Determining Eligibility for Use of the Device (Responders) — 94 percentage of participants
Respiratory Syncytial Viruses
Primary: Number of Participants With Treatment Emergent Adverse Events (TEAEs) — 6; 7; 4; 9 Participants
Relative Energy Deficiency in Sport
Primary: Change in Bone Remodeling Biomarker - N-terminal Propeptide of Type 1 Procollagen — -3.1; 1.1 ng/mL — p=0.246
Alcohol and Substance-Related Mental Disorders · Sexually Transmitted Diseases
Primary: Feasibility of Providing Intervention — 25; 22 Participants
Polycystic Ovary Syndrome (PCOS)
Primary: Lipid Content of PCOS Subcutaneous (SC) Abdominal Adipocytes Matured in Vitro. — 2.0; 5.6; 1.37; 3.8 fluorescence units/cell number — p=0.004
Healthy
Primary: Mean Score of Sensory Attributes Based on Palatability Assessment Questionnaire at 1 Minute Post-dose on Day 1 — 80.3; 49.4; 54.0; 48.5 Units on a scale
Bone Loss · Hypotensive · Lower Limb Fluid Pooling
Primary: Bone Density of Proximal Femur — -0.133; -.675; 1.3 percent change in bone density
Healthy Participants
Primary: Maximum Plasma Concentration (Cmax) of Spironolactone and Hydrochlorothiazide Following a Single Oral Dose of Spironolactone/Hydrochlorothiazide 25/25 mg Film Coated…
Obesity · Overweight · Binge Eating
Primary: Changes in Food-cue Visual Probe Task Attention Bias (AB) Reaction Time — 1.85; 4.27 Change in milliseconds
Healthy Participants
Primary: Area Under the Serum Concentration-Time Profile From Time Zero to 24 Hours (AUC0-24) of Etrasimod: Tasso PK Sampling — 666.4; 745.5 Nanogram*hour per milliliter…
Healthy Volunteers
Primary: Part 1: Mean Cumulative Amount of Total Radioactivity (CumAe) of [14C]-GDC-9545 Excreted in Urine, Feces, and Total (Urine and Feces Combined) Over the Entire Collection…
Autonomic Nervous System Imbalance · Hypothalamic Pituitary Adrenal Axis Suppression
Primary: Change From Baseline to Post Intervention High Frequency (HF) and Low Frequency Divided by High Frequency (LF/HF) Power Amplitude — 0.1796; 0.1507; -0.3872; 0.3731…
Tobacco Use Disorder
Primary: Number of Cigarettes Smoked Per Day — 22.54; 14.32; 11.76; 7.63 cigarettes per day
Healthy Volunteers
Primary: Maximum Observed Concentration (Cmax) of Ritlecitinib: MR Capsules vs Oral Solution Under Fasted Condition — 671.6; 145.1; 84.96 Nanogram per milliliter (ng/mL)
Ascites Hepatic
Primary: Incidence of Treatment-Emergent Adverse Events — 1; 0; 2; 1 Participants