Phase 2 N=482 Reducing Preterm Births in Underserved Pregnant Women
Preterm Birth · Low Birth Weight <2500 Grams · Verylow Birthweight <1500 Grams
Primary: Birthweight — 40; 26 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=11,976 Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)
Premature Birth
Primary: Incidence of Preterm Birth — 668; 754 Participants — p=0.012
Phase 3 N=321 17OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet Pregnancies
Preterm Birth
Primary: Newborn Respiratory Distress Syndrome (RDS) — 44; 18 Twins
N/A N=118 Weight Management for Improved Pregnancy Outcomes
Obesity · Pregnancy
Primary: Maternal Weight Change — 1.2; -2.6 kg
Phase 3 N=2,464 High Dose Folic Acid Supplementation Throughout Pregnancy for Preeclampsia Prevention
Pregnancy Complications · Preeclampsia
Primary: Preeclampsia — 169; 156 Participants — p=0.37
N/A N=46 Prevention of Preterm Birth With a Pessary in Twin Gestations
Premature Birth · Short Cervix
Primary: Number of Participants With Preterm Delivery — 9; 8 Participants
N/A N=360 Lifestyle and Pregnancy: The Clinical Effect of Lifestyle Intervention During Pregnancy in Obese Women
Maternal Obesity · Gestational Weight Gain · Obstetric Complications
Primary: Cesarean Section
N/A N=5 Randomized Clinical Trial: Expectant Management vs Laser Treatment of Monochorionic Twins With Severe Selective Intrauterine Growth Retardation and Absent or Reverse Diastolic Flow in the Umbilical Artery
Intrauterine Growth Retardation
Primary: Survival — 100; 100 percentage of AGA babies who survived
N/A N=16 Acute Exercise Effects in Obese Pregnancy
Pregnancy Complications · Obesity · Pre-Eclampsia
Primary: Oral Glucose Insulin Sensitivity (OGIS) Index — 405.0; 426.0; 418.9 uU/mL
N/A N=995 Neonatal Outcome by Reason for Delivery
Preterm Delivery
Primary: Composite Perinatal Morbidity — 277; 203; 221; 45 participants
Phase 2 N=100 Brief Intervention in At-Risk First-time Mothers
Substance Use
Primary: Alcohol Use — 1.37; 0.92 units on a scale
N/A N=299 Healthy Lifestyle Intervention for High-Risk Minority Pregnant Women
Emotional Disturbances · Depression · Pregnancy Late
Primary: Change in Self-reported Healthy Lifestyle Beliefs Timepoint 0 to Timepoint 3 — 59.044; 59.349; 64.972; 64.234 units on a scale — p=<0.001
N/A N=224 Nudge to Drive Transitions of Care
Preeclampsia · Preeclampsia Severe · Gestational Hypertension
Primary: Number of Patients With Documented Counseling on Transitions of Care — 38; 28 Participants
N/A N=95 Early Screening and Treatment of Women With Prediabetes in Pregnancy
Diabetes · Pregnancy
Primary: Number of Patients With a Diagnosis of Gestational Diabetes at 26 Weeks Gestation. — 19; 23 Participants — p=0.32
N/A N=32 Centering Pregnancy Care + Yoga for Diverse Pregnant Women
Pregnancy
Primary: Feasibility of Retention/ Adherence — 15; 17 Participants
N/A N=144 The Use of Progesterone to Reduce Preterm Birth
Preterm Birth
Primary: Weeks Gestation at Birth Among Patients Receiving the Active Drug. — 31.9; 30.2 weeks
N/A N=452 Low Plasma Mannose Binding Lectin (p-MBL) Level is a Risk Factor for Recurrent Pregnancy Loss (RPL)
Recurrent Miscarriage · Spontaneous Abortion · Mannose-Binding Lectin Deficiency
Primary: Plasma MBL Level (ug/ml) — 717; 1717 ug/l — p=<0.001
N/A N=313 Linking Inter-professional Newborn and Contraception Care
Family Planning · Contraception · PostPartum
Primary: Number of Patients Who Receive Contraception by Two Months Postpartum — 474; 339 Participants — p=0.12
N/A N=151 Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia
Cardiovascular Disease · Preeclampsia · Hypertension
Primary: Eating Habits Confidence Survey — 4.2; 4.5 units on a scale
N/A N=343 Comprehensive Postpartum Management for Women With Hypertensive Disorders of Pregnancy
Hypertension, Pregnancy-Induced · Postpartum Preeclampsia · Hypertension; Maternal
Primary: Proportion of Participants With Recorded Blood Pressure Values in Office — 43; 44; 49; 56 Participants
N/A N=360 Participate While Pregnant Survey
Pregnancy
Primary: Willingness to Participate in Research While Pregnant — 319; 39; 288; 70 Participants
Phase 3 N=10,154 Combined Antioxidant and Preeclampsia Prediction Studies (CAPPS)
Preeclampsia
Primary: Composite of Pregnancy-associated Hypertension and Serious Adverse Outcomes in the Mother or Fetus or Neonate — 305; 285 Participants — p=0.42
Phase 3 N=220 Effectiveness of Higher Aspirin Dosing for Prevention of Preeclampsia in High Risk Obese Gravida
Pre-Eclampsia · Hypertension in Pregnancy · Obesity
Primary: Number of Participants With Preeclampsia Diagnosis With Severe Features Based on Clinician Diagnosis — 37; 41 Participants
N/A N=236 Tennessee Connections for Better Birth Outcomes
Preterm Birth
Primary: Infant Gestational Age — 38.14; 38.14 weeks — p=.64
N/A N=6 Heart Rate Variability and Prematurity
Premature Birth · Maternal Distress - Delivered · Stress
Primary: Feasibility: Acceptance (Ratio) — 33.3 percentage of <participants>
N/A N=51 Sedentary Behavior Reduction in Pregnancy Intervention Study
Pregnancy Complications · Sedentary Behavior
Primary: Sedentary Time — 10.42; 10.52; 9.62; 10.38 total hours/day — p=<0.05
N/A N=29 Prenatal Mindfulness & Hypertension Study
Hypertension in Pregnancy
Primary: Retention and Adherence — 12; 11 Participants
N/A N=70 Using Mental Imagination to Prevent Excessive Gestational Weight Gain in Overweight and Obese Pregnant Women
Obesity · Weight Gain, Maternal
Primary: Percent Change in Body Weight — 10.9; 9.6 percentage change
N/A N=1,200 Happy Mother-Healthy Baby: An Anxiety-focused Early Prenatal Intervention
Postpartum Depression · Small for Gestational Age at Delivery · Preterm Birth
Primary: Number of Participants With Combined Common Mental Disorders (CMDs, i.e. Anxiety and Depression). — 57; 178 Participants
N/A N=122 Prevention of Preterm Birth With a Pessary in Singleton Gestations
Preterm Birth · Short Cervix
Primary: Number of Subjects Experiencing Preterm Birth — 26; 23 Participants