N/A N=55 Oxytocin Pathways and the Health Effects of Human-Animal Interaction
Human-Animal Bond · Human-Animal Interaction
Primary: Salivary Oxytocin, Area Under the Curve — -3.03; -3.83; -5.57 pg/mL x minutes
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=74 Impact of Human-Animal Interactions on Children With Life-Threatening Conditions and Their Parents
Advanced Cancer · Relapsed Cancer · Refractory Cancer
Primary: Pediatric Quality of Life — 47.6; 50.3; 61.6; 41.5 score on a scale
N/A N=40 Animal Assisted Therapy in Dentistry
Anxiety
Primary: Mean Salivary Amylase Levels Throughout Dental Visit — 150.82; 166.70; 127.77; 145.39 U/mL — p=0.379
N/A N=33 Integrating Animal-Assisted Therapy Into Trauma-Focused Cognitive-Behavioral Therapy for Maltreated Youth
Child Abuse · Posttraumatic Stress
Primary: Change in Scores on the UCLA Posttraumatic Stress Disorder Reaction Index — 44.63; 39.5; 22.64; 35.85 units on a scale
N/A N=75 Assessing Mechanisms of Anxiety Reduction in Animal-assisted Interventions
Social Anxiety Disorder · Social Anxiety · Social Anxiety Disorder of Childhood
Primary: Self-reported Affective Experience — 10.19; 10.00; 10.28; 8.33 units on a scale — p=.723
N/A N=22 Effects of Animal-assisted Therapy on Brain-injured Patients
Impaired Social Functioning
Primary: Social Functioning: Total Social Behavior — 29.22; 8.68 percentage of shown behavior
N/A N=17 Assessing an Animal-Assisted Treatment Program for Adults With Aphasia: The Persons With Aphasia Training Dogs Program
Aphasia
Primary: Assessment of Living With Aphasia (ALA, Kagan et al., 2010) — 2.67; 2.33; 2.68; 2.43 units on a scale
N/A N=36 Development and Evaluation CAT and Youth
CAT Intervention Group · Control Group
Primary: Number of Participants Whose Cats Changed From Insecure to Secure Attachment Classification From T1 to T3 — 6; 1 Participants — p=.0156
N/A N=19 Wildlife and Wellbeing: An Animal-Assisted Intervention for Veterans With PTSD
Stress Disorders, Post-Traumatic
Primary: Incidence of Recruitment of Study Participants — 19 participants
N/A N=39 Animal Assisted Intervention With Dogs for Children With ADHD
Attention Deficit Hyperactivity Disorder
Primary: ADHD-Rating Scale (ADHD-RS) at 8 Weeks — 29.0; 23.9 units on a scale
N/A N=19 Animal Assisted Interactions With Animal Robot in the Intensive Care Unit (ICU)
Acute Lymphoblastic Leukemia (ALL) · Critical Illness · Physical Therapy Modalities
Primary: Pain: Wrong-Baker FACES Pain Rating Scale — 3.94 units on a scale
Early Phase 1 N=19 A Study of Dog Adoption in Veterans With Posttraumatic Stress Disorder (PTSD)
Posttraumatic Stress Disorder (PTSD)
Primary: Change in PTSD Checklist (PCL-5) Score Between Baseline and 3-month Follow-up — -15.20; -7.77 units on a scale — p=0.141
N/A N=31 Feasibility and Acceptability Off The Equus Effect
Social Skills · Emotional Dysfunction
Primary: Social Adjustment Scale-Self Report (SAS-SR) — 2.92; 2.92; 2.30; 2.32 score on a scale — p=<0.05
N/A N=211 Pawsitive Impacts of Therapy Dog Visits
Pain · Pain, Acute · Pain, Chronic
Primary: Number of Participants Stratified by Edmonton Symptom Assessment System (Revised Version) (ESAS-r) Pain Scores — 50; 43; 7; 7 Participants
N/A N=26 Tandem VR: Synchronized Nature-Based Experiences in Virtual Reality for Hospice Patients and Their Caregivers
Hospice · End of Life · Palliative Care
Primary: Quality of Life Domains — 1.68; 1.27 units on a scale
N/A N=160 Examining Transcutaneous Vagal Nerve Stimulation as a Facilitator of Social Bonding
Vagus Nerve Stimulation
Primary: Self-reported Positive Affect — 5.89; 5.69 units on a scale
N/A N=270 The Biology of Resilience
Oxytocin · Placebo
Primary: Systolic Blood Pressure Change From Baseline to Second Stress Task Experience - Autonomic Stress Response Measure — 9.4; 12.9; 11.3; 11.1 mm Hg — p=0.03
Phase 1 N=69 A Website to Teach Children Safety With Dogs
Child Dog Bite Prevention
Primary: Children's Behavior With Dogs on Standardized Objective Scale — 1.4; 1.6 units on a scale
N/A N=60 Service Dog Training Program for Military Veterans With PTSD
Post Traumatic Stress Disorder
Primary: Post Traumatic Stress Symptom Severity — 43.7; 38.9; 35.1; 31.6 score on a scale
N/A N=38 Attachment and Biobehavioral Catch-up and Depression Treatment
Maternal Depression · Child Behavior Problem
Primary: Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Depression Score — 6.70; 6.98 units on a scale — p=.85
N/A N=10 Holding, Stress, and Bonding During Therapeutic Hypothermia
Hypoxic-Ischemic Encephalopathy
Primary: Frequency of Adverse Events (Safety) — 0 Participants
N/A N=170 Quantifying the Efficacy and Role of Service Dogs for Military Veterans With PTSD
Post Traumatic Stress Disorder
Primary: PTSD Severity and Symptoms Via Self-report — 41.9; 51.7 units on a scale — p=<.001